strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
GCA_000523715.1,xenopi,1789,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCA_000523715.1_AMRSEG0001,JAOC01000002.1,positive,7379-10795,97.25,80.37,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2014/1/27,664.0,,
GCA_000523715.1,xenopi,1789,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCA_000523715.1_AMRSEG0002,JAOC01000005.1,negative,165347-165662,91.59,85.13,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2014/1/27,664.0,,
GCA_000523715.1,xenopi,1789,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,GCA_000523715.1_AMRSEG0003,JAOC01000008.1,positive,112411-112955,99.82,80.37,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2014/1/27,664.0,,
GCA_000523715.1,xenopi,1789,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCA_000523715.1_AMRSEG0004,JAOC01000014.1,negative,4152-4838,100.0,87.48,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2014/1/27,664.0,,
GCA_000523715.1,xenopi,1789,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCA_000523715.1_AMRSEG0005,JAOC01000031.1,positive,107129-107813,99.71,87.34,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2014/1/27,664.0,,
GCF_000257745.1,xenopi,1789,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_000257745.1_AMRSEG0001,NZ_AJFI01000016.1,positive,5908-6223,91.59,85.13,,,,Netherlands,2012/4/5,128.0,,
GCF_000257745.1,xenopi,1789,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_000257745.1_AMRSEG0002,NZ_AJFI01000030.1,negative,6020-6706,100.0,87.34,,,,Netherlands,2012/4/5,128.0,,
GCF_000257745.1,xenopi,1789,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,GCF_000257745.1_AMRSEG0003,NZ_AJFI01000097.1,negative,11021-11565,99.82,80.37,,,,Netherlands,2012/4/5,128.0,,
GCF_000257745.1,xenopi,1789,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_000257745.1_AMRSEG0004,NZ_AJFI01000116.1,positive,1565-4984,97.33,80.43,,,,Netherlands,2012/4/5,128.0,,
GCF_900453395.1,xenopi,1789,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_900453395.1_AMRSEG0001,NZ_UATA01000001.1,negative,465802-466117,91.59,85.13,,,,,2018/6/30,597.0,,
GCF_900453395.1,xenopi,1789,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,GCF_900453395.1_AMRSEG0002,NZ_UATA01000015.1,negative,246438-246982,99.82,80.37,,,,,2018/6/30,597.0,,
GCF_900453395.1,xenopi,1789,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_900453395.1_AMRSEG0003,NZ_UATA01000015.1,positive,803687-807106,97.33,80.4,,,,,2018/6/30,597.0,,
GCF_900453395.1,xenopi,1789,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_900453395.1_AMRSEG0004,NZ_UATA01000016.1,negative,119500-120186,100.0,87.48,,,,,2018/6/30,597.0,,