| Title |
Proteogenomic Landscape of Human Breast Ductal Carcinoma Progression |
| Description |
In this study, we carried out a comprehensive proteogenomic analysis of 402 samples from 299 patients with malignant and benign breast diseases. Proteogenomic analysis revealed the characteristics of linear multi-step progression of BRDC. In addition, we identified AKR1C1 as a potential therapeutic target and demonstrated the inhibitory effect of its inhibitors aspirin and dydrogesterone on tumor cells. |
| Organism |
Homo sapiens |
| Data Type |
Clinical Research data |
| Data Accessibility |
Controlled-access |
| BioProject |
PRJCA011514 |
| Release Date |
2022-08-31 |
| Submitter |
Yingyong Hou (houyingyong@aliyun.com) |
| Organization |
Zhongshan Hospital, Fudan University |
| Submission Date |
2022-08-29 |