Proteogenomic Landscape of Human Breast Ductal Carcinoma Progression
| Title | Proteogenomic Landscape of Human Breast Ductal Carcinoma Progression |
|---|---|
| Description | In this study, we carried out a comprehensive proteogenomic analysis of 402 samples from 299 patients with malignant and benign breast diseases. Proteogenomic analysis revealed the characteristics of linear multi-step progression of BRDC. In addition, we identified AKR1C1 as a potential therapeutic target and demonstrated the inhibitory effect of its inhibitors aspirin and dydrogesterone on tumor cells. |
| Organism | Homo sapiens |
| Data Type | Clinical Research data |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA011514 |
| Release Date | 2022-08-31 |
| Submitter | Yingyong Hou (houyingyong@aliyun.com) |
| Organization | Zhongshan Hospital, Fudan University |
| Submission Date | 2022-08-29 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX001714-01 | Clinical information | 402 | Clinical Research data | 46.5 KB | xlsx | 0 | Controlled |
| OMIX001714-02 | Transcriptomic data | 22 | Clinical Research data | 3.7 MB | xlsx | 0 | Controlled |
| OMIX001714-03 | Phosphoproteomic data | 75 | Clinical Research data | 4.4 MB | xlsx | 0 | Controlled |
| OMIX001714-04 | Genomic data | 116 | Clinical Research data | 5.1 MB | xlsx | 0 | Controlled |
| OMIX001714-05 | Proteomic data | 402 | Clinical Research data | 62.16 MB | xlsx | 0 | Controlled |