| Title | Single-cell transcriptome reveals the beneficially regulatory effects of artesunate on splenic immune cells in polymicrobial sepsis |
|---|---|
| Description | In this study, we performed single-cell RNA transcriptome sequencing (scRNA-seq) to investigate the protective effect and underlying mechanism of ART on the splenic microenvironment in spleen of the cecal ligation and puncture (CLP)-induced sepsis model. |
| Organism | Mus |
| Data Type | Expression Profiling |
| Data Accessibility | Open-access |
| BioProject | PRJCA012821 |
| Release Date | 2023-06-26 |
| Submitter | WANG CHEN (cwang1992@icmm.ac.cn) |
| Organization | Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences |
| Submission Date | 2022-10-27 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX002221-01 | CLP3 | 1 | Expression Profiling | 69.88 MB | tar | |
| OMIX002221-02 | CLP2 | 1 | Expression Profiling | 47.32 MB | tar | |
| OMIX002221-03 | CLP1 | 1 | Expression Profiling | 59.13 MB | tar | |
| OMIX002221-04 | Sham3 | 1 | Expression Profiling | 69.87 MB | tar | |
| OMIX002221-05 | Sham2 | 1 | Expression Profiling | 71.28 MB | tar | |
| OMIX002221-06 | ART3 | 1 | Expression Profiling | 73.33 MB | tar | |
| OMIX002221-07 | Sham1 | 1 | Expression Profiling | 27.01 MB | tar | |
| OMIX002221-08 | ART1 | 1 | Expression Profiling | 70.18 MB | tar | |
| OMIX002221-09 | ART2 | 1 | Expression Profiling | 57.3 MB | tar |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| Single-cell transcriptome analysis reveals the regulatory effects of artesunate on splenic immune cells in polymicrobial sepsis | Journal of Pharmaceutical Analysis | 2023-02 | OMIX002221 | Deposit |
| Improving SCVI for low-count cells through self-supervised augmentation | bioRxiv | 2026-02 | OMIX002221 | Deposit |