TERT C228T and KDM6A alterations are potential predictive biomarkers in non-muscle-invasive bladder cancer treated with intravesical BCG instillation
| Title | TERT C228T and KDM6A alterations are potential predictive biomarkers in non-muscle-invasive bladder cancer treated with intravesical BCG instillation |
|---|---|
| Description | BCG is the standard of care for high risk non-muscle-invasive bladder cancer (NMIBC) following transurethral resection. However, patients often have heterogeneous response. Even among those who initially respond well to BCG, 10-20% relapse. Identification of reliable biomarkers predicting the efficacy of BCG remains an unmet need. En bloc resection is a novel technique that represents a substantial advancement in the surgical management of NMIBC. We sought to investigate genomic and tumor microenviromental (TME) profiles of en bloc resected NMIBC and explore potential predictive markers for BCG treatment. |
| Organism | Homo sapiens |
| Data Type | Other Type of Genomic Data |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA013209 |
| Release Date | 2023-10-08 |
| Submitter | Shao-Gang Wang (sgwangtjm@163.com) |
| Organization | Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology |
| Submission Date | 2022-11-14 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX002345-01 | mutation and MAP | 1 | Other Type of Genomic Data | 77.2 KB | rar | 0 | Unavailable |