| Title | Single-cell transcriptomic profiling reveals the tumor heterogeneity of small-cell lung cancer |
|---|---|
| Description | Here, we performed high-precision single-cell transcriptomic analysis of ~5000 individual cells from primary tumors (PTs) and matched normal adjacent tissues (NATs) from 11 SCLC patients, including one patient with both PT and relapsed tumor (RT). We revealed a heterogeneous cellular architecture of this malignant cancer at single-cell resolution. |
| Organism | Homo sapiens |
| Data Type | Expression Profiling |
| Data Accessibility | Open-access |
| BioProject | PRJCA006026 |
| Release Date | 2024-02-28 |
| Submitter | Fuchou Tang (tangfuchou@pku.edu.cn) |
| Organization | Peking University |
| Submission Date | 2022-11-23 |
HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client).
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX002441-01 | SCLC_cell_count_matrix | 1 | Expression Profiling | 237.24 MB | csv | |
| OMIX002441-02 | SCLC_cell_info | 1 | Expression Profiling | 344 KB | csv |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| A four gene risk score model for prognosis and immune microenvironment insights in small cell lung cancer based on CAF functional-related genes | Discover Oncology | 2025-05 | OMIX002441 | Secondary use |
| ATAD2 is a potential immunotherapy target for patients with small cell lung cancer harboring HLA-A∗0201 | eBioMedicine | 2025-01 | OMIX002441 | Deposit |
| Single-cell transcriptomic profiling reveals the tumor heterogeneity of small-cell lung cancer | Signal Transduction and Targeted Therapy | 2022-11 | OMIX002441 | Deposit |
| A DNA Nanomachine Modulates the Stemness-Associated Signaling Pathways for Overcoming Chemoresistance by Temporally Programming Drug Release | Research | 2025-12 | OMIX002441 | Secondary use |