Transcriptomic profiling of the stiffness-induced dormant cells in oral squamous cell carcinoma
| Title | Transcriptomic profiling of the stiffness-induced dormant cells in oral squamous cell carcinoma |
|---|---|
| Description | Dormancy is a crucial machinery for cancer cells to survive hostile microenvironment. Dormant tumor cells are considered as the major cause of post-treatment relapse and metastases, which are the two main factors that dramatically impair patient prognosis in oral squamous cell carcinoma (OSCC). However, the regulatory mechanism of tumor cell dormancy in OSCC is unclear. We found that stiffness-related mechanical stress (MS) induces a dormant subpopulation in OSCC. Here we used RNA-seq to further characterize the transcriptomic alterations in this stiffness-induced dormant subpopulation. |
| Organism | Homo sapiens |
| Data Type | Expression Profiling by NGS |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA013934 |
| Release Date | 2024-09-01 |
| Submitter | Jingyuan Li (BarneyLJY@outlook.com) |
| Organization | Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University |
| Submission Date | 2022-12-17 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX002623-01 | Expression profile | 1 | Expression Profiling by NGS | 18.8 MB | xls | 0 | Unavailable |