| Title | Integrated analysis toolkit for dissecting whole-genome-wide features of cell-free DNA |
|---|---|
| Description | Patterns in whole-genome-wide features of cell-free DNA (cfDNA) in human plasma provide a noninvasive diagnostic approach for cancer detection. However, an integrated analysis toolkit for whole-genome-wide features of cfDNA (INAC) is lacking. In this study, these cfDNA whole-genome features, including cfDNA quality control, fragment size, fragment size ratio, copy number variation, transcription start site (TSS) relative coverage, and promoter fragmentation entropy, were estimated by using the INAC toolkit to analyze a collected independent dataset (50 patients with gastric cancer and 50 healthy controls) with ~10x sequence depth. |
| Organism | Homo sapiens |
| Data Type | Other Type of Genomic Data |
| Data Accessibility | Open-access |
| BioProject | PRJCA013939 |
| Release Date | 2023-07-19 |
| Submitter | Xun Lan (xlan@tsinghua.edu.cn) |
| Organization | Tsinghua University |
| Submission Date | 2023-02-05 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX002911-01 | fragment_size_ratio | 100 | Other Type of Genomic Data | 4.79 MB | txt | Unavailable |
| OMIX002911-02 | copy_num | 100 | Other Type of Genomic Data | 41.12 MB | txt | Unavailable |
| OMIX002911-03 | TSS_NDR_coverage | 100 | Other Type of Genomic Data | 52.9 MB | txt | Unavailable |
| OMIX002911-04 | TSS_conventional_coverage | 100 | Other Type of Genomic Data | 52.62 MB | txt | Unavailable |
| OMIX002911-05 | TSS_2K_coverage | 100 | Other Type of Genomic Data | 30.03 MB | txt | Unavailable |
| OMIX002911-06 | PFE | 100 | Other Type of Genomic Data | 52.42 MB | txt | Unavailable |
| OMIX002911-07 | TF_1ksites_AccessibilityAllHighFreq | 100 | Other Type of Genomic Data | 213.37 KB | txt | Unavailable |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| Integrated analysis toolkit for dissecting whole‐genome‐wide features of cell‐free DNA | Clinical and Translational Medicine | 2023-05 | OMIX002910 OMIX002911 | Deposit |