| Title |
change of peripheral neutrophils subsets after acute ischemic stroke |
| Description |
Neutrophils usually participate in the inflammatory response at an early stage, and their numbers increase rapidly after acute cerebral infarction and infiltrate into the brain tissue. In recent years, more and more studies have shown that neutrophils contain at least two functionally opposed subgroups. So far, there is no perfect and unified classification system for neutrophils because researchers have not yet formed a consensus on neutrophil clustering markers. Previous studies on the role of neutrophils in acute cerebral infarction mostly believed that the role of neutrophils was negative. However, the discovery of neutrophil heterogeneity has a great impact on the previous understanding. The roles of two groups of neutrophils with opposite functions in cerebral infarction are completely opposite. The changes of each subset of neutrophils after cerebral infarction and their roles and mechanisms in cerebral ischemic injury are still unclear. |
| Organism |
Mus |
| Data Type |
Expression Profiling by Array |
| Data Accessibility |
Open-access |
| BioProject |
PRJCA014966 |
| Release Date |
2024-12-31 |
| Submitter |
Jiachun Feng (fengjcfrank@126.com) |
| Organization |
Department of Neurology, First Affiliated Hospital of Jilin University |
| Submission Date |
2023-02-15 |