Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease.
| Title | Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease. |
|---|---|
| Description | They were able to successfully design, synthesize and evaluate two lead inhibitors of SARS-CoV-2 main protease. Interestingly, they were able to crystallize protease-inhibitor complex to visualize real chemical interaction involved. |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
| Data Type | Protein 3D Structure Data |
| Data Accessibility | Open-access |
| BioProject | PRJCA015329 |
| Release Date | 2023-03-04 |
| Submitter | Xiuna Yang (yangxn@shanghaitech.edu.cn) |
| Organization | ShanghaiTech University |
| Submission Date | 2023-03-03 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
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| OMIX003220-01 | They were able to successfully design, synthesize and evaluate two lead inhibitors of SARS-CoV-2 main protease. Interestingly, they were able to crystallize protease-inhibitor complex to visualize real chemical interaction involved | 1 | Protein 3D Structure Data | 233.7 KB | zip | 0 |