A Genetically Encoded Two-Dimensional Infrared Probe for Enzyme Active-Site Dynamics
| Title | A Genetically Encoded Two-Dimensional Infrared Probe for Enzyme Active-Site Dynamics |
|---|---|
| Description | A genetically encoded two-dimensional infrared probe, N3Y, was developed for monitoring femtosecond to picosecond water dynamics and conformational flexibility of enzyme active sites. The addition of a low concentration of desaturating reagent decreased active-site water motion confinement, which is correlated with a decrease in enzyme activity. |
| Organism | Methanocaldococcus jannaschii |
| Data Type | Proteomic Data by Mass Spectrometry (MS) |
| Data Accessibility | Open-access |
| BioProject | PRJCA016795 |
| Release Date | 2023-05-09 |
| Submitter | Lin Liu (liulin@ibp.ac.cn) |
| Organization | Insititute of Biophysics, Chinese Academy of Sciences |
| Submission Date | 2023-05-08 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX003965-01 | Two-dimensional infrared probe N3Y mass spectrometry NMR data | 4 | Proteomic Data by Mass Spectrometry (MS) | 2.5 MB | zip | 0 |