Simulated conformation ensembles for chromatin for eight developmental stages from HPSC cells based on DNase-seq data
Title | Simulated conformation ensembles for chromatin for eight developmental stages from HPSC cells based on DNase-seq data |
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Description | In our work, we develop a polymer-physics-based hypothesis-driven model, noted as our stochastic folding model. This model predicts the conformation ensemble of a chromatin region of interest by using only the population-averaged chromatin accessibility data as input. We use stochastic folding model to construct the conformation ensemble for two chromatin regions: chr11:15Mb-25Mb and chr12:105Mb-115Mb. For each cell, the conformation ensemble is generated using the DNase-seq data |
Organism | Mus |
Data Type | Other Type of Genomic Data |
Data Accessibility | Open-access |
BioProject | PRJCA017011 |
Release Date | 2023-05-16 |
Submitter | Luming MENG (menglum@scau.edu.cn) |
Organization | South China Agricultural University |
Submission Date | 2023-05-16 |
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File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
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OMIX004067-01 | Simulated conformation ensembles for chromatin for eight developmental stages from HPSC cells based on DNase-seq data | 16 | Other Type of Genomic Data | 142.92 MB | tar | 0 |