Integrated proteomic and transcriptomic landscape of macrophages in mouse tissues
| Title | Integrated proteomic and transcriptomic landscape of macrophages in mouse tissues |
|---|---|
| Description | Here we use mass spectrometry and bulk RNA sequencing to assess the proteomic and transcriptomic patterns, respectively, of 10 primary macrophage populations from seven mouse tissues, bone marrow-derived macrophages and the cell line RAW264.7. The results show distinct proteomic landscape and protein copy numbers between tissue-resident and recruited macrophages. Construction of a hierarchical regulatory network finds cell type-specific transcription factors of macrophages serving as hubs for denoting tissue and functional identity of individual macrophage subsets. |
| Organism | Mus musculus |
| Data Type | Proteomic Data by Mass Spectrometry (MS) |
| Data Accessibility | Open-access |
| BioProject | PRJCA017718 |
| Release Date | 2023-06-21 |
| Submitter | PUMIN ZHANG (pzhangbcm@zju.edu.cn) |
| Organization | Beijing Proteome Research Center |
| Submission Date | 2023-06-19 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX004371-01 | BMDM1 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.46 GB | zip | 0 | |
| OMIX004371-02 | BMDM2 | 6 | Proteomic Data by Mass Spectrometry (MS) | 4.27 GB | zip | 0 | |
| OMIX004371-03 | BMDM3 | 6 | Proteomic Data by Mass Spectrometry (MS) | 4.15 GB | zip | 0 | |
| OMIX004371-04 | Colonic1 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.49 GB | zip | 0 | |
| OMIX004371-05 | Colonic2 | 6 | Proteomic Data by Mass Spectrometry (MS) | 2.98 GB | zip | 0 | |
| OMIX004371-06 | Colonic3 | 6 | Proteomic Data by Mass Spectrometry (MS) | 4.42 GB | zip | 0 | |
| OMIX004371-07 | Ileal1 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.38 GB | zip | 0 | |
| OMIX004371-08 | Ileal2 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.3 GB | zip | 0 | |
| OMIX004371-09 | Ileal3 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.9 GB | zip | 0 | |
| OMIX004371-10 | KC1 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.56 GB | zip | 0 | |
| OMIX004371-11 | KC2 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.02 GB | zip | 0 | |
| OMIX004371-12 | KC3 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.67 GB | zip | 0 | |
| OMIX004371-13 | Liverrec1 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.36 GB | zip | 0 | |
| OMIX004371-14 | Liverrec2 | 6 | Proteomic Data by Mass Spectrometry (MS) | 4.47 GB | zip | 0 | |
| OMIX004371-15 | Liverrec3 | 6 | Proteomic Data by Mass Spectrometry (MS) | 4.26 GB | zip | 0 | |
| OMIX004371-16 | lung_resi1 | 6 | Proteomic Data by Mass Spectrometry (MS) | 4.01 GB | zip | 0 | |
| OMIX004371-17 | lung_resi2 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.79 GB | zip | 0 | |
| OMIX004371-18 | lung_resi3 | 6 | Proteomic Data by Mass Spectrometry (MS) | 4.39 GB | zip | 0 | |
| OMIX004371-19 | lungrec1 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.5 GB | zip | 0 | |
| OMIX004371-20 | lungrec2 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.33 GB | zip | 0 | |
| OMIX004371-21 | lungrec3 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.9 GB | zip | 0 | |
| OMIX004371-22 | Microglia1 | 6 | Proteomic Data by Mass Spectrometry (MS) | 1.05 GB | zip | 0 | |
| OMIX004371-23 | Microglia2 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.58 GB | zip | 0 | |
| OMIX004371-24 | Microglia3 | 6 | Proteomic Data by Mass Spectrometry (MS) | 4.27 GB | zip | 0 | |
| OMIX004371-25 | PM1 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.83 GB | zip | 0 | |
| OMIX004371-26 | PM2 | 6 | Proteomic Data by Mass Spectrometry (MS) | 4.18 GB | zip | 0 | |
| OMIX004371-27 | PM3 | 6 | Proteomic Data by Mass Spectrometry (MS) | 4.12 GB | zip | 0 | |
| OMIX004371-28 | RAW2 | 6 | Proteomic Data by Mass Spectrometry (MS) | 4.34 GB | zip | 0 | |
| OMIX004371-29 | RAW3 | 6 | Proteomic Data by Mass Spectrometry (MS) | 4.53 GB | zip | 0 | |
| OMIX004371-30 | Spleenrec1 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.76 GB | zip | 0 | |
| OMIX004371-31 | Spleenrec2 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.98 GB | zip | 0 | |
| OMIX004371-32 | Spleenrec3 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.17 GB | zip | 0 | |
| OMIX004371-33 | Spleenresi1 | 6 | Proteomic Data by Mass Spectrometry (MS) | 4.11 GB | zip | 0 | |
| OMIX004371-34 | Spleenresi2 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.41 GB | zip | 0 | |
| OMIX004371-35 | Spleenresi3 | 6 | Proteomic Data by Mass Spectrometry (MS) | 3.67 GB | zip | 0 |