Changes of metabolites in urine of IBS-D rats after acupuncture treatment
Title | Changes of metabolites in urine of IBS-D rats after acupuncture treatment |
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Description | Acupuncture can attenuate visceral hyperalgesia and alleviate the symptoms of diarrhea-predominant irritable bowel syndrome (IBS-D). In this study, 18 Sprague-Dawley rats aged 4 weeks were randomly divided into three groups:[1]healthy control group;[2]IBS-D model rats;[3]Acupuncture treatment of IBS-D rats (n = 6). The disease model of IBS-D rats was established by rectal dilatation. Acupuncture treatment group (IBSDacu): IBS-D rats were acupuncture for 20 minutes every day, and selected acupoints ST25 (Tianshu) and BL25 (Dachangshu) for 14 days. Urine of rats was collected and metabonomics was studied by positive and negative ion mode of mass spectrometer. |
Organism | Rattus |
Data Type | Metabolome Data by Mass Spectrometry (MS) |
Data Accessibility | Open-access |
BioProject | PRJCA018144 |
Release Date | 2023-07-10 |
Submitter | Shen Guo-ming (doctor2023222@163.com) |
Organization | Anhui University of Traditional Chinese Medicine |
Submission Date | 2023-07-07 |
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File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
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OMIX004487-01 | samples&detect information | 2 | Metabolome Data by Mass Spectrometry (MS) | 25.56 KB | zip | 0 | |
OMIX004487-02 | clean data | 4 | Metabolome Data by Mass Spectrometry (MS) | 5.74 MB | zip | 0 | |
OMIX004487-03 | MS negtive iron mode data | 21 | Metabolome Data by Mass Spectrometry (MS) | 494.83 MB | zip | 0 | |
OMIX004487-04 | MS positive iron mode data | 21 | Metabolome Data by Mass Spectrometry (MS) | 1.16 GB | zip | 0 |