GBA1 variants in a Chinese cohort with Parkinson disease
| Title | GBA1 variants in a Chinese cohort with Parkinson disease |
|---|---|
| Description | GBA1 variants are important risk factors for Parkinson disease (PD). Most studies assessing GBA1-related PD risk have been performed in European-derived populations. There are some analysis of coding region of GBA1 gene in Asian population, while the sample sizes of which were not large. This study aims to investigate GBA1 variants in a large Chinese cohort of patients with PD and health controls, and explored their clinical characteristics. GBA1 variants in 4,034 patients and 2,931 controls were investigated using whole-exome sequencing (WES) and whole-genome sequencing (WGS). Clinical features of patients were evaluated using several scales. |
| Organism | Homo sapiens |
| Data Type | Other Type of Genomic Data |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA018318 |
| Release Date | 2023-07-13 |
| Submitter | Beisha Tang (bstang7398@163.com) |
| Organization | Xiangya Hospital, Central South University |
| Submission Date | 2023-07-13 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX004514-01 | Variants info of GBA1 | 6965 | Other Type of Genomic Data | 18.8 KB | xlsx | 0 | Unavailable |