Single-cell multi-omics analysis reveals a dynamic immune trajectory of recovery in liver transplantation patients
| Title | Single-cell multi-omics analysis reveals a dynamic immune trajectory of recovery in liver transplantation patients |
|---|---|
| Description | Reestablishment of immune homeostasis under the tacrolimus-based immunosuppressive treatment after liver transplantation (LT) is essential for long-term graft survival. However, little is known about the dynamic changes of immune remodeling after LT for providing reference to the precise and dynamic management of immunosuppressants treatment in the clinic. Herein, we mapped the dynamic immune cell compositions and functions alteration of the peripheral immune microenvironment at single-cell resolution in patients with and without acute cellular rejection (ACR) in the scenario with treatment of tacrolimus based immunosuppressive regimen after LT. |
| Organism | Homo sapiens |
| Data Type | Expression Profiling by Array |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA015796 |
| Release Date | 2024-04-07 |
| Submitter | Zhihai Peng (zhpeng@xah.xmu.edu.cn) |
| Organization | Xiangan Hospital of Xiamen university |
| Submission Date | 2023-07-29 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX004645-01 | CellTypeInfo | 1 | Expression Profiling by Array | 703.46 KB | rar | 0 | Unavailable |
| OMIX004645-02 | pbmc_data | 1 | Expression Profiling by Array | 73.62 MB | rar | 0 | Unavailable |
| OMIX004645-03 | cytof_data | 19 | Expression Profiling by Array | 358.54 MB | rar | 0 | Unavailable |
| OMIX004645-04 | cytof_metadata | 1 | Expression Profiling by Array | 8.43 KB | rar | 0 | Unavailable |