Oligodendrocyte progenitor cell-specific delivery of lipid nanoparticle loaded with Olig2 synthetically modified messenger RNA for ischemic stroke therapy
| Title | Oligodendrocyte progenitor cell-specific delivery of lipid nanoparticle loaded with Olig2 synthetically modified messenger RNA for ischemic stroke therapy |
|---|---|
| Description | In order to explore how the molecular and oligodendrocyte-specific gene expression profiles of cerebral infarction area were altered in C-Olig2-treated mouse hippocampi compared to those in Mock-treated mouse hippocampi, we performed transcriptome analysis of hippocampal samples from the four groups at the single-cell level by snRNA-seq. We sampled 15,505 nuclei: 9821, 1502, 2079 and 2203 from the Sham, Mock, I-Olig2 and C-Olig2 groups, respectively. |
| Organism | Mus musculus |
| Data Type | Expression Profiling by NGS |
| Data Accessibility | Open-access |
| BioProject | PRJCA019877 |
| Release Date | 2023-12-15 |
| Submitter | Xiaofan Mao (xiaofanmao@126.com) |
| Organization | The First People's Hospital of Foshan |
| Submission Date | 2023-09-18 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX004950-01 | Integrated Seurat object | 4 | Expression Profiling by NGS | 619.48 MB | rds | 0 |