Differentiation route determines the functional outputs of adult megakaryopoiesis
| Title | Differentiation route determines the functional outputs of adult megakaryopoiesis |
|---|---|
| Description | To compare the functional outputs of megakaryopoiesis through the direct and stepwise differentiation routes, scRNA-seq was performed with purified CD41+ MKs spanning different ploidy (from 2N to 32N) from six 2-month-old *Cd48dre;R26rox-tdTomato* mice under normal and stress condition. The ploidy tomato expression under different conditions are available in MK_meta_data.csv. The expression pattern of megakayocytes are available in MK_counts.csv. Mouse cell cycle genes used in cell cycle analysis: please see mouse_cell_cycle_genes.rds. |
| Organism | Mus |
| Data Type | Expression Profiling by NGS |
| Data Accessibility | Open-access |
| BioProject | PRJCA015388 |
| Release Date | 2024-03-07 |
| Submitter | Qianfei Wang (wangqf@big.ac.cn) |
| Organization | Beijing Institute of Genomics, Chinese Academy of Sciences |
| Submission Date | 2023-12-01 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX005321-04 | mouse_cell_cycle_genes.rds | 1 | Expression Profiling by NGS | 534 bytes | rds | 0 | |
| OMIX005321-05 | MK_meta_data.csv | 1 | Expression Profiling by NGS | 89.1 KB | csv | 0 | |
| OMIX005321-06 | MK_counts.csv | 1 | Expression Profiling by NGS | 208.4 MB | csv | 0 |