OMIX005321

1Summary
Title Differentiation route determines the functional outputs of adult megakaryopoiesis
Description To compare the functional outputs of megakaryopoiesis through the direct and stepwise differentiation routes, scRNA-seq was performed with purified CD41+ MKs spanning different ploidy (from 2N to 32N) from six 2-month-old *Cd48dre;R26rox-tdTomato* mice under normal and stress condition. The ploidy tomato expression under different conditions are available in MK_meta_data.csv. The expression pattern of megakayocytes are available in MK_counts.csv. Mouse cell cycle genes used in cell cycle analysis: please see mouse_cell_cycle_genes.rds.
Organism Mus
Data Type Expression Profiling
Data Accessibility Open-access
BioProject PRJCA015388
Release Date 2024-03-07
Submitter Qianfei Wang (wangqf@big.ac.cn)
Organization Beijing Institute of Genomics, Chinese Academy of Sciences
Submission Date 2023-12-01
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX005321-04 mouse_cell_cycle_genes.rds 1 Expression Profiling 534 bytes rds
OMIX005321-05 MK_meta_data.csv 1 Expression Profiling 89.1 KB csv
OMIX005321-06 MK_counts.csv 1 Expression Profiling 208.4 MB csv
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
Differentiation route determines the functional outputs of adult megakaryopoiesis Immunity 2024-03 OMIX005321 Deposit

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