OMIX

EGFR/ALK/ROS1and TMB/MSI gene mutation detection data of 708 subjects from study HLX10-002-NSCLC301

OMIX005645

1Summary
Title EGFR/ALK/ROS1and TMB/MSI gene mutation detection data of 708 subjects from study HLX10-002-NSCLC301
Description EGFR/ALK/ROS1and TMB/MSI gene mutation detection data of 708 subjects from study HLX10-002-NSCLC301:A Three-Arm, Randomised, Double-Blind, Multicentre, Phase III Clinical Study to Evaluate HLX10 (Recombinant Humanised Anti-PD-1 Monoclonal Antibody Injection) in Combination with Chemotherapy (Carboplatin-Pemetrexed) Versus HLX10 + HLX04 (Recombinant Anti-VEGF Humanised Monoclonal Antibody Injection) in Combination with Chemotherapy (Carboplatin-Pemetrexed) Versus Chemotherapy (Carboplatin-Pemetrexed) as First-Line Treatment of Advanced Non-Squamous Non-Small Cell Lung Cancer (NSCLC). The purpose of this study was to evaluate the clinical efficacy, safety, and tolerability of HLX10 combined chemotherapy and HLX10+HLX04 combined chemotherapy versus chemotherapy in subjects who had not previously received systemic treatment for advanced non-squamous NSCLC, collect PK parameters, and explore biomarkers related to efficacy.
Organism Homo sapiens
Data Type Other Type of Genomic Data
Data Accessibility Controlled-access
BioProject PRJCA022783
Release Date 2024-01-12
Submitter xinyu Sun (xinyu_sun@henlius.com)
Organization Shanghai Henlius Biotech,Inc.
Submission Date 2024-01-11
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download Times Download
OMIX005645-01 HLX10-002-NSCLC301_EGFR ALK ROS1 TMB MSI gene mutation detection data of 708 subjects 1 Other Type of Genomic Data 41.5 KB xlsx 0 Controlled

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