| Title | DNA methylation in human aging process |
|---|---|
| Description | In this study, we identified 126,420 clock-like DNA methylation sites (ClockDML) within the human genome. This was achieved through bisulfite capture sequencing of CpG island regions in peripheral blood mononuclear cells, sourced from a diverse age range of donors. We then calculated the correlation coefficient between age and the methylation level at each locus. The DNA methylation status of these ClockDML exhibited a strong correlation with age in our study group. |
| Organism | Homo sapiens |
| Data Type | Methylation Profiling |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA023202 |
| Release Date | 2024-04-25 |
| Submitter | KaiYu Qian (qky1009@whu.edu.cn) |
| Organization | Zhongnan hospital of Wuhan University |
| Submission Date | 2024-02-06 |
HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client).
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX005823-01 | human.aging.methylKit.tar | 71 | Methylation Profiling | 10.96 GB | tar | Controlled |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| Tracking single-cell evolution using clock-like chromatin accessibility loci | Nature Biotechnology | 2024-05 | OMIX005824 OMIX005823 | Deposit |