OMIX

Sini San ameliorates hepatocyte apoptosis through regulating Intestinal Flora and SCFAs in CCL4-induced hepatic fibrosis mice

OMIX006041

1Summary
Title Sini San ameliorates hepatocyte apoptosis through regulating Intestinal Flora and SCFAs in CCL4-induced hepatic fibrosis mice
Description The UPLC-ESI-MS/MS analytical method was used for the qualitative and quantitative detection of the target metabolites, and the specific analytical conditions and analytical methods were as follows: The chromatographic column was ACQUITY UPLC BRHC18 (100*2.1mm, 1.7um), Waters; the high performance liquid chromatograph was Nexera UHPLC LC-30A, Shimadzu, Japan; Chromatographic conditions: Injection volume: 5 μL; Flow rate: 0.35 mL/min; Gradient Elution Procedures (GEP): 0 min A/B (90:10, V/V), 1 min A/B (90:10, V/V), 2 min A/B (75:25, V/V), 6 min A/B (65:35, V/V), 6.5 min A/B (5:95, V/V). 7.8 min A/B (5:95, V/V), 7.81 min A/B (90:10, V/V), 8.5 min A/B (90:10, V/V).A highly sensitive mass spectrometer AB Sciex Qtrap 5500, AB Sciex was used. Mass spectrometry conditions: Curtain gas: 35 (psi); Collision-activated dissociation (CAD) parameters: medium; Positive ion spray voltage: 5500V; negative ion spray voltage: -4500V; Ion source temperature: 450°C; Column temperature: 40°C;
Organism Mus musculus
Data Type Metabolome Data by Mass Spectrometry (MS)
Data Accessibility Open-access
BioProject PRJCA024508
Release Date 2024-03-21
Submitter qiong wu (2638794343@qq.com)
Organization First Affiliated Hospital of Anhui Medical University
Submission Date 2024-03-20
2Files & Download

HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client).

File ID File Title Number/Samples File Type File Size File Suffix Download Times Download
OMIX006041-01 CCL4-induced mice 8 Metabolome Data by Mass Spectrometry (MS) 4.68 MB zip 0

View All Released Data of OMIX