Disruption of maternal vascular remodelling by a fetal endoretrovirus in preeclampsia
| Title | Disruption of maternal vascular remodelling by a fetal endoretrovirus in preeclampsia |
|---|---|
| Description | Preeclampsia (PE), one of the most lethal pregnancy-related diseases, is associated with the disruption of uterine spiral artery remodeling during placentation. However, the early molecular events leading to PE remain unknown. Here, by analyzing placentas from PE, non-PE, and twin pregnancies with selective intrauterine growth restriction, we showed that the pathogenesis of PE is attributed to immature trophoblast and maldeveloped endothelial cells. |
| Organism | Homo sapiens |
| Data Type | Other Type of Genomic Data |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA006679 |
| Release Date | 2024-04-02 |
| Submitter | Yuan Wei (weiyuanbysy@163.com) |
| Organization | Peking University Third Hospital |
| Submission Date | 2024-04-02 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX006123-01 | Placenta_scATAC_fragment.tsv.gz.tar.gz | 1 | Other Type of Genomic Data | 14.98 GB | tar.gz | 0 | Unavailable |
| OMIX006123-02 | CutTag_bigwig_gzfile.tar.gz | 54 | Other Type of Genomic Data | 6.5 GB | tar.gz | 0 | Unavailable |
| OMIX006123-03 | mkdup_CpG_gzfile.tar.gz | 43 | Other Type of Genomic Data | 8.87 GB | tar.gz | 0 | Unavailable |
| OMIX006123-04 | scRNA_mtx_gzfile.tar.gz | 9 | Other Type of Genomic Data | 328.63 MB | tar.gz | 0 | Unavailable |
| OMIX006123-05 | bulkATAC_bigwig_gzfile.tar.gz | 15 | Other Type of Genomic Data | 3.75 GB | tar.gz | 0 | Unavailable |