| Title | JointMap: A Unified Platform for Chondral Studies and Articular Diseases |
|---|---|
| Description | The articular cartilage plays a crucial key role in smooth articulation and load transmission of bones. Diverse methods based on recent progress in single-cell technologies were performed for molecular characterization of the heterogeneous cell types within articular cartilage. Here, we present an integrated reference atlas for the chondral structures, JointMap. The spatial preferences of chondrocyte subtypes were speculated by the collected tissues of samples and spatial module scores. The multi-omic annotations in single-cell level were calculated. Collectively, JointMap provides a unified framework for the systematic analysis of chondral structures across multiple species, and it can serve as an important platform to unravel druggable networks for treating articular diseases. |
| Organism | mixed sample |
| Data Type | Expression Profiling |
| Data Accessibility | Open-access |
| BioProject | PRJCA028746 |
| Release Date | 2025-10-05 |
| Submitter | Xiaoqing Hu (huxiaoqingbd01@sina.com) |
| Organization | Institute of Sports Medicine, Peking University Third Hospital |
| Submission Date | 2024-08-01 |
HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client).
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX007049-01 | VSMC_Count | 1 | Expression Profiling | 591.24 MB | csv | |
| OMIX007049-02 | Muscle_Count | 1 | Expression Profiling | 2.02 GB | csv | |
| OMIX007049-03 | Chondrocyte_Reduction_Celltype | 1 | Expression Profiling | 12.95 MB | csv | |
| OMIX007049-04 | EndC_Reduction_Subtype | 1 | Expression Profiling | 705.84 KB | csv | |
| OMIX007049-05 | EndC_Reduction_Celltype | 1 | Expression Profiling | 707.06 KB | csv | |
| OMIX007049-06 | ImmC_Reduction_Subtype | 1 | Expression Profiling | 2.58 MB | csv | |
| OMIX007049-07 | EndC_Count | 1 | Expression Profiling | 548.47 MB | csv | |
| OMIX007049-09 | Progenitor_Metadata | 1 | Expression Profiling | 83.38 MB | csv | |
| OMIX007049-10 | Progenitor_Reduction_Celltype | 1 | Expression Profiling | 16.53 MB | csv | |
| OMIX007049-11 | ImmC_Metadata | 1 | Expression Profiling | 14.1 MB | csv | |
| OMIX007049-12 | Progenitor_Reduction_Subtype | 1 | Expression Profiling | 16.54 MB | csv | |
| OMIX007049-13 | Muscle_Reduction_Celltype | 1 | Expression Profiling | 1.69 MB | csv | |
| OMIX007049-14 | VSMC_Reduction_Celltype | 1 | Expression Profiling | 715.65 KB | csv | |
| OMIX007049-15 | Chondrocyte_Count | 1 | Expression Profiling | 9.01 GB | csv | |
| OMIX007049-16 | ImmC_Reduction_Celltype | 1 | Expression Profiling | 2.59 MB | csv | |
| OMIX007049-17 | EndC_Metadata | 1 | Expression Profiling | 3.75 MB | csv | |
| OMIX007049-18 | Muscle_Metadata | 1 | Expression Profiling | 8.32 MB | csv | |
| OMIX007049-19 | Chondrocyte_Metadata | 1 | Expression Profiling | 66.17 MB | csv | |
| OMIX007049-20 | Chondrocyte_Reduction_Subtype | 1 | Expression Profiling | 12.74 MB | csv | |
| OMIX007049-21 | VSMC_Reduction_Subtype | 1 | Expression Profiling | 710.63 KB | csv | |
| OMIX007049-22 | Progenitor_Count | 1 | Expression Profiling | 17.87 GB | csv | |
| OMIX007049-23 | ImmC_Count | 1 | Expression Profiling | 1.85 GB | csv | |
| OMIX007049-24 | VSMC_Metadata | 1 | Expression Profiling | 3.62 MB | csv | |
| OMIX007049-25 | Muscle_Reduction_Subtype | 1 | Expression Profiling | 1.69 MB | csv | |
| OMIX007049-26 | Read_me | 1 | Expression Profiling | 392 bytes | txt | |
| OMIX007049-28 | Multi_Omic__and__Spatial_module_score.csv | 1 | Expression Profiling | 410.31 MB | csv |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| JointMap identified SERPINA3+ chondrocytes as a therapeutic target for osteoarthritis | bioRxiv | 2025-09 | OMIX007049 | Deposit |