SILAC of HepG2 or HepAD38 cell lines with HBV
Title | SILAC of HepG2 or HepAD38 cell lines with HBV |
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Description | Hepatitis B Virus constitutes a major threat to global public health by infecting hepatocytes, initiating and driving the progress to end-stage liver disease and liver cancer. Curing treatment for HBV infection is yet unavailable, mainly due to unmet gaps in current understanding of HBV-host interaction. Here, multi-omics interrogations were conducted to generate the first landscape of HBV-induced global changes in host transcriptome, translatome and proteome, which identified multiple translatomic events that HBV orchestrated to remodel host proteostasis networks and afford micro-environments essential for HBV proliferation and persistence. |
Organism | Homo sapiens |
Data Type | Proteomic Data by Mass Spectrometry (MS) |
Data Accessibility | Controlled-access |
BioProject | PRJCA030580 |
Release Date | 2024-09-27 |
Submitter | Ronggui Hu (coryhu00@gmail.com) |
Organization | Zhejiang University |
Submission Date | 2024-09-27 |
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File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
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OMIX007521-01 | rep3_MIX3 | 24 | Proteomic Data by Mass Spectrometry (MS) | 3.34 GB | tar.gz | 0 | Controlled |
OMIX007521-02 | rep1_MIX1 | 24 | Proteomic Data by Mass Spectrometry (MS) | 2.74 GB | tar.gz | 0 | Controlled |
OMIX007521-03 | rep2_MIX2 | 24 | Proteomic Data by Mass Spectrometry (MS) | 2.75 GB | tar.gz | 0 | Controlled |