| Title | cross-species transcriptomic atlas reveals cell lineage fidelity in human embryo models |
|---|---|
| Description | We integrated published single-cell RNA-seq datasets from human (Homo sapiens) and cynomolgus monkey (Macaca fascicularis) embryos spanning peri-implantation to early gastrulation, including both in vivo and in vitro cultured (IVC) samples. A harmonized cell type annotation system was established, defining 49 human and 55 macaque cell types across embryonic and extraembryonic lineages, including epiblast, trophoblast, hypoblast, germ layers, and key progenitors. Each annotation is associated with its predominant developmental stage. Original annotations are retained for traceability. This resource provides a standardized reference for cell identity annotation, cross-study comparison, and evaluation of stem cell-derived embryo models in primate development. |
| Organism | mixed sample |
| Data Type | Expression Profiling |
| Data Accessibility | Open-access |
| BioProject | PRJCA045416 |
| Release Date | 2025-09-05 |
| Submitter | Xueying Fan (fanxueying@westlake.edu.cn) |
| Organization | Westlake University |
| Submission Date | 2025-08-29 |
HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client).
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX011658-01 | monkey Post-Implantation Embryo Cell Atlas | 1 | Expression Profiling | 2.88 GB | tar.gz | |
| OMIX011658-02 | Human Post-Implantation Embryo Cell Atlas | 1 | Expression Profiling | 1.46 GB | tar.gz | |
| OMIX011658-03 | Human and monkey cross-species Post-Implantation Embryo Cell Atlas | 1 | Expression Profiling | 5.15 GB | tar.gz |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
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