Reversible deafness and blindness in Cryptococcus gattii meningitis with a ventriculoperitoneal shunt: a case report and literature review
| Title | Reversible deafness and blindness in Cryptococcus gattii meningitis with a ventriculoperitoneal shunt: a case report and literature review |
|---|---|
| Description | Cryptococcus gattii (C. gattii) has been considered a leading cause of meningitis in immunocompetent hosts in tropical and subtropical regions. Visual loss is common but hearing impairment is relatively infrequent in C. gattii meningitis. Notably, there have been limited studies and cases on the etiology, and especially therapy of auditory and ocular complications associated with C. gattii meningitis. Here we report a case of reversible deafness and blindness treated with a ventriculoperitoneal shunt (VPS) surgery in C. gattii meningitis. This case indicates that the elevated intracranial pressure (ICP) may play a role in concurrent loss of hearing and vision associated with C. gattii meningitis and an early VPS surgery after the initiation of the antifungal therapy may effectively improve both hearing and vision in this condition. |
| Organism | Cryptococcus gattii VGII |
| Data Type | - |
| Data Accessibility | Open-access |
| BioProject | PRJCA008439 |
| Release Date | 2022-04-25 |
| Submitter | Ye Zhang (zhangye@hugobiotech.com) |
| Organization | Hugobiotech Beijing Co.,Ltd. |
| Submission Date | 2022-02-25 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX975-04-01 | 7311166423_Cryptococcus_gattii_VGII | 1 | Genome-Wide Association Study (GWAS) | 17.1 KB | fasta | 0 | |
| OMIX975-04-02 | 1911157679_Cryptococcus_gattii_VGII | 1 | Genome-Wide Association Study (GWAS) | 76.2 KB | fasta | 0 |