Salivary proteins as predictors and controls for oral health.

Dusa Vukosavljevic, William Custodio, Walter L Siqueira
Author Information
  1. Dusa Vukosavljevic: Biomedical Engineering Graduate Program, The University of Western Ontario, Dental Sciences Building, DSB 0015, London, ON, N6A 5C1, Canada, dvukosav@uwo.ca.

Abstract

We will provide a translational view of using the recent technological advances in dental research for predicting, monitoring, and preventing the development of oral diseases by investigating the diagnostic and therapeutic role of salivary proteins. New analytical state-of-the-art technologies such as mass spectrometry and atomic force microscopy have revolutionized the field of oral biology. These novel technologies open avenues for a comprehensive characterization of the salivary proteins followed by the evaluation of the physiological functions which could make possible in a near future the development of a new series of synthetic protein for therapeutic propose able to prevent global oral diseases such as periodontal disease and dental caries, the two most prevalent oral diseases in the World.

References

Microbiology (Reading). 1996 Mar;142 ( Pt 3):631-638 [PMID: 8868438]
J Appl Bacteriol. 1996 Feb;80(2):124-30 [PMID: 8642010]
Appl Environ Microbiol. 2001 Mar;67(3):1343-50 [PMID: 11229930]
J Clin Microbiol. 2005 Nov;43(11):5721-32 [PMID: 16272510]
J Dent Res. 1994 Nov;73(11):1748-55 [PMID: 7983262]
Clin Oral Investig. 2007 Dec;11(4):361-8 [PMID: 17522902]
CA Cancer J Clin. 2002 Jul-Aug;52(4):195-215 [PMID: 12139232]
Annu Rev Biophys Biomol Struct. 2007;36:171-90 [PMID: 17328679]
J Periodontol. 1999 Jan;70(1):13-29 [PMID: 10052767]
Acta Odontol Scand. 1995 Dec;53(6):358-62 [PMID: 8849868]
Annu Rev Phys Chem. 2004;55:457-507 [PMID: 15117260]
Infect Immun. 1994 Aug;62(8):3372-80 [PMID: 8039907]
Oral Dis. 2011 May;17(4):345-54 [PMID: 21122035]
Periodontol 2000. 2002;29:31-69 [PMID: 12102702]
Periodontol 2000. 1997 Jun;14:173-201 [PMID: 9567971]
Infect Immun. 1991 Aug;59(8):2549-54 [PMID: 1855975]
Ann N Y Acad Sci. 2007 Mar;1098:504-9 [PMID: 17435160]
Scand J Dent Res. 1983 Apr;91(2):112-7 [PMID: 6304864]
Cancer Epidemiol Biomarkers Prev. 2007 Jul;16(7):1348-55 [PMID: 17627000]
FEMS Yeast Res. 2009 Oct;9(7):1102-10 [PMID: 19799638]
Infect Immun. 1988 Feb;56(2):439-45 [PMID: 2892794]
Biophys J. 2009 Feb;96(3):1218-31 [PMID: 19186156]
J Clin Periodontol. 1998 Feb;25(2):134-44 [PMID: 9495612]
Arch Oral Biol. 2009 May;54(5):437-44 [PMID: 19268279]
J Dent Res. 2010 Oct;89(10):1016-23 [PMID: 20739693]
FEMS Yeast Res. 2006 Nov;6(7):979-86 [PMID: 17042747]
J Biol Chem. 1986 Jan 25;261(3):1177-82 [PMID: 3944083]
Crit Rev Oral Biol Med. 1997;8(2):175-200 [PMID: 9167092]
Int J Cancer. 1988 Feb 15;41(2):184-97 [PMID: 3338870]
Scand J Dent Res. 1987 Apr;95(2):151-8 [PMID: 3470908]
Br Dent J. 1992 Apr 25;172(8):305-12 [PMID: 1591115]
Annu Rev Microbiol. 1996;50:513-52 [PMID: 8905090]
Anal Chem. 2009 Mar 15;81(6):2106-14 [PMID: 19192965]
Contemp Clin Dent. 2010 Jan;1(1):17-22 [PMID: 22114372]
Infect Immun. 1991 Sep;59(9):2948-54 [PMID: 1879920]
J Dent Res. 1987 May;66(5):1016-9 [PMID: 3475317]
J Indian Soc Periodontol. 2010 Oct;14(4):207-12 [PMID: 21731243]
Methods Enzymol. 1999;310:216-24 [PMID: 10547795]
Microbiology (Reading). 1995 Jan;141 ( Pt 1):213-9 [PMID: 7894715]
Ann Periodontol. 1998 Jul;3(1):51-61 [PMID: 9722690]
Science. 2003 Nov 7;302(5647):1002-5 [PMID: 14605360]
Biochem J. 1984 May 1;219(3):833-42 [PMID: 6234886]
CA Cancer J Clin. 2005 Mar-Apr;55(2):74-108 [PMID: 15761078]
J Dent Res. 1994 Oct;73(10):1627-35 [PMID: 7523468]
Microbiology (Reading). 2003 Feb;149(Pt 2):279-294 [PMID: 12624191]
APMIS. 1995 May;103(5):339-44 [PMID: 7654358]
J Proteome Res. 2007 Jun;6(6):2152-60 [PMID: 17447804]
Proteomics Clin Appl. 2011 Dec;5(11-12):575-9 [PMID: 21956964]
J Am Dent Assoc. 2000 Jul;131(7):887-99 [PMID: 10916327]

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