- Jennifer E Platt: 1Department of Psychiatry, UMDNJ-Robert Wood Johnson Medical School, Piscataway, NJ; 2Department of Psychiatry, Columbia University Medical Center, New York, NY; and 3Platt Psychiatric Associates, Cedar Grove, NJ.
Zonisamide is an anticonvulsant used as an adjunctive treatment for partial seizures. It has also been used off-label for treatment of mania. Abdoh et al recently reported a very interesting case of psychosis induced by zonisamide. We too observed a case of psychosis induced by zonisamide in a 34-year-old female with bipolar disorder and narcolepsy.