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Biology direct
Nov 28, 2012;7 43; discussion 43.

Bioinformatics clouds for big data manipulation.

Lin Dai, Xin Gao, Yan Guo, Jingfa Xiao, Zhang Zhang
Author Information
  1. Lin Dai: CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, No.7 Beitucheng West Road, Building G, Chaoyang District, Beijing 100029, China.
PMID: 23190475 DOI: 10.1186/1745-6150-7-43

Abstract

As advances in life sciences and information technology bring profound influences on bioinformatics due to its interdisciplinary nature, bioinformatics is experiencing a new leap-forward from in-house computing infrastructure into utility-supplied cloud computing delivered over the Internet, in order to handle the vast quantities of biological data generated by high-throughput experimental technologies. Albeit relatively new, cloud computing promises to address big data storage and analysis issues in the bioinformatics field. Here we review extant cloud-based services in bioinformatics, classify them into Data as a Service (DaaS), Software as a Service (SaaS), Platform as a Service (PaaS), and Infrastructure as a Service (IaaS), and present our perspectives on the adoption of cloud computing in bioinformatics.
REVIEWERS: This article was reviewed by Frank Eisenhaber, Igor Zhulin, and Sandor Pongor.

References

  1. Bioinformatics. 2008 Jan 15;24(2):299-301 [PMID: 18037613]
  2. J Intern Med. 2012 Feb;271(2):122-30 [PMID: 22142244]
  3. J Biomed Inform. 2010 Apr;43(2):342-53 [PMID: 19715773]
  4. Brief Bioinform. 2009 Jan;10(1):1-10 [PMID: 18842678]
  5. PLoS One. 2010 Apr 14;5(4):e10071 [PMID: 20418944]
  6. Genome Biol. 2010;11(5):207 [PMID: 20441614]
  7. BMC Bioinformatics. 2010 Dec 21;11 Suppl 12:S1 [PMID: 21210976]
  8. Nat Biotechnol. 2011 Nov 08;29(11):972-4 [PMID: 22068528]
  9. BMC Bioinformatics. 2011 Aug 30;12:356 [PMID: 21878105]
  10. Nat Rev Genet. 2010 Sep;11(9):647-57 [PMID: 20717155]
  11. Genome Med. 2010 Aug 06;2(8):51 [PMID: 20691073]
  12. Bioinformatics. 2012 Mar 1;28(5):721-3 [PMID: 22257667]
  13. Bioinformatics. 2012 Jan 15;28(2):294-5 [PMID: 22084254]
  14. Genome Biol. 2009;10(11):R134 [PMID: 19930550]
  15. Bioinformatics. 2012 Sep 1;28(17):2267-9 [PMID: 22743228]
  16. Brief Bioinform. 2003 Sep;4(3):208-9 [PMID: 14582515]
  17. BMC Bioinformatics. 2012 Mar 19;13:42 [PMID: 22429538]
  18. BMC Bioinformatics. 2010 Dec 21;11 Suppl 12:S4 [PMID: 21210983]
  19. Bioinformatics. 2012 Jun 1;28(11):1542-3 [PMID: 22492314]
  20. Bioinformatics. 2009 Jun 1;25(11):1363-9 [PMID: 19357099]
  21. Science. 2011 Jan 28;331(6016):406-7 [PMID: 21273473]
  22. BMC Bioinformatics. 2010 May 18;11:259 [PMID: 20482786]
  23. Bioinformatics. 2011 Apr 15;27(8):1045-51 [PMID: 21367868]
  24. BMC Res Notes. 2011 Jun 06;4:171 [PMID: 21645377]
  25. BMC Bioinformatics. 2011 May 09;12:139 [PMID: 21554709]
  26. Nat Biotechnol. 2010 Jul;28(7):691-3 [PMID: 20622843]
  27. Bioinformatics. 2012 Jun 1;28(11):1415-9 [PMID: 22556365]
  28. Nat Biotechnol. 2012 Apr 10;30(4):295-6 [PMID: 22491260]
  29. Bioinformatics. 2011 Mar 15;27(6):860-2 [PMID: 21252073]
  30. Genome Biol. 2010;11(8):R83 [PMID: 20701754]
  31. Nat Biotechnol. 2010 Nov;28(11):1181-5 [PMID: 21057489]
  32. Nat Biotechnol. 2012 Jun 07;30(6):509-11 [PMID: 22678394]
  33. PLoS Comput Biol. 2011 Aug;7(8):e1002147 [PMID: 21901085]
  34. Nat Rev Genet. 2011 Mar;12(3):224 [PMID: 21301474]

MeSH Term

Access to Information
Computational Biology
Data Collection
Information Storage and Retrieval
Internet
Software
User-Computer Interface
Evaluation Study Journal Article Research Support, Non-U.S. Gov't Review

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