Comparison of Eye Drop Instillation Before and After Use of Drop Application Strips in Glaucoma Patients on Chronic Topical Therapy.

Reetika Sharma, Deepali Singhal, Adarsh Shashni, Esha Agarwal, Meenakshi Wadhwani, Tanuj Dada
Author Information
  1. Reetika Sharma: Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Abstract

PURPOSE: To evaluate the impact of using drop application strips on eye drop instillation in glaucoma patients on chronic topical ocular hypotensive therapy.
METHODS: A total of 72 patients with primary open-angle glaucoma with an uncorrected visual acuity of 3/60 or more, self-administering topical antiglaucoma medication for >1 year were evaluated. One eye of each patient was included in the study. Patients were instructed to instill 0.5% carboxymethyl cellulose drop in 1 eye. They were then instructed to instill the same drop using the drop application strips.
RESULTS: Mean age of the patients included in the study was 50.39 ± 12.04 years. Before assistance of drop application strips, 35 (48.61%) patients placed the drop into the eye without any contact of the dropper nozzle, and, after application of the drop application strips, 66 (91.67%) patients placed the drop in the eye without any contact (P=0.025). The number of patients putting the first drop of drug into the eye without spilling over the adenexae increased from 30 (41.67%) to 45 (62.5%) after application of the strip (P<0.001). The mean number of drops instilled to get 1 drop into the eye decreased from 2 ± 0.95 to 1.56 ± 0.78 when the drop application strip was used (P<0.001).
CONCLUSIONS: Use of a drop application strip causes a significant decrease in contact of the eye drop bottle nozzle with the eyeball and eyelid, decreases the number of drops instilled to get 1 drop into the eye, and is associated with an overall improvement in eye drop instillation.

MeSH Term

Administration, Topical
Adult
Aged
Antihypertensive Agents
Drug Delivery Systems
Drug Packaging
Female
Glaucoma, Open-Angle
Humans
Intraocular Pressure
Male
Middle Aged
Ophthalmic Solutions
Self Administration
Surveys and Questionnaires
Visual Acuity
Young Adult

Chemicals

Antihypertensive Agents
Ophthalmic Solutions

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