Nanowires: Quantitative Probing of Cu(2+) Ions Naturally Present in Single Living Cells (Adv. Mater. 21/2016).

Junho Lee, Hwa-Rim Lee, Jaeyeon Pyo, Youngseob Jung, Ji-Young Seo, Hye Guk Ryu, Kyong-Tai Kim, Jung Ho Je
Author Information
  1. Junho Lee: X-Ray Imaging Center, Department of Materials Science and Engineering, Pohang University of Science and Technology, Pohang, 790-784, Korea.
  2. Hwa-Rim Lee: School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang, 790-784, Korea.
  3. Jaeyeon Pyo: X-Ray Imaging Center, Department of Materials Science and Engineering, Pohang University of Science and Technology, Pohang, 790-784, Korea.
  4. Youngseob Jung: Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang, 790-784, Korea.
  5. Ji-Young Seo: Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang, 790-784, Korea.
  6. Hye Guk Ryu: Department of Life Sciences, Pohang University of Science and Technology, Pohang, 790-784, Korea.
  7. Kyong-Tai Kim: School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang, 790-784, Korea.
  8. Jung Ho Je: X-Ray Imaging Center, Department of Materials Science and Engineering, Pohang University of Science and Technology, Pohang, 790-784, Korea.

Abstract

Quantitative probing of the Cu(2+) ions naturally present in single living cells is accomplished by a probe made from a quantum-dot-embedded-nanowire waveguide. After inserting the active nanowire-based waveguide probe into single living cells, J. H. Je and co-workers directly observe photoluminescence (PL) quenching of the embedded quantum dots by the Cu(2+) ions diffused into the probe as described on page 4071. This results in quantitative measurement of intracellular Cu(2+) ions.

Keywords

MeSH Term

Cations, Divalent
Cell Survival
Copper
Nanowires
Quantum Dots

Chemicals

Cations, Divalent
Copper

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