Precision Medicine: What Challenges Are We Facing?

Yu Xue, Eric-Wubbo Lameijer, Kai Ye, Kunlin Zhang, Suhua Chang, Xiaoyue Wang, Jianmin Wu, Ge Gao, Fangqing Zhao, Jian Li, Chunsheng Han, Shuhua Xu, Jingfa Xiao, Xuerui Yang, Xiaomin Ying, Xuegong Zhang, Wei-Hua Chen, Yun Liu, Zhang Zhang, Kun Huang, Jun Yu
Author Information
  1. Yu Xue: MOE Key Laboratory of Molecular Biophysics, College of Life Science and Technology and the Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan 430074, China.
  2. Eric-Wubbo Lameijer: School of Electronic and Information Engineering, Xi'an Jiaotong University, Xi'an 710049, China.
  3. Kai Ye: School of Electronic and Information Engineering, Xi'an Jiaotong University, Xi'an 710049, China.
  4. Kunlin Zhang: CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China.
  5. Suhua Chang: CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China.
  6. Xiaoyue Wang: State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100005, China.
  7. Jianmin Wu: MOE/Beijing Key Laboratory of Carcinogenesis and Translational Research, Center for Cancer Bioinformatics, Peking University Cancer Hospital & Institute, Beijing 100142, China.
  8. Ge Gao: Center for Bioinformatics, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing 100871, China.
  9. Fangqing Zhao: Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, China.
  10. Jian Li: MOE Key Laboratory of Developmental Genes and Human Disease, Institute of Life Sciences, Southeast University, Nanjing 210096, China.
  11. Chunsheng Han: State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
  12. Shuhua Xu: Max Planck Independent Research Group on Population Genomics, CAS-MPG Partner Institute for Computational Biology (PICB), Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
  13. Jingfa Xiao: CAS Key Laboratory of Genome Sciences and Information, Chinese Academy of Sciences, Beijing 100101, China.
  14. Xuerui Yang: MOE Key Laboratory of Bioinformatics, School of Life Sciences, Center for Synthetic and Systems Biology, Tsinghua University, Beijing 100084, China.
  15. Xiaomin Ying: Computational Omics Laboratory, Center of Computational Biology, Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
  16. Xuegong Zhang: Bioinformatics Division, TNLIST and MOE Key Laboratory for Bioinformatics, Department of Automation, Tsinghua University, Beijing 100084, China.
  17. Wei-Hua Chen: Department of Bioinformatics and Systems Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
  18. Yun Liu: MOE Key Laboratory of Metabolism and Molecular Medicine, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.
  19. Zhang Zhang: BIG Data Center and CAS Key Laboratory of Genome Sciences & Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China.
  20. Kun Huang: Department of Biomedical Informatics, The Ohio State University, Columbus, OH 43017, USA.
  21. Jun Yu: CAS Key Laboratory of Genome Sciences and Information, Chinese Academy of Sciences, Beijing 100101, China. Electronic address: junyu@big.ac.cn.

Abstract

No abstract text available.

References

  1. Nucleic Acids Res. 2011 Jul;39(Web Server issue):W567-75 [PMID: 21715388]
  2. Nat Rev Genet. 2016 Jul;17 (7):392-406 [PMID: 27140283]
  3. Nature. 2015 Oct 15;526(7573):336-42 [PMID: 26469044]
  4. J Urol. 2015 Nov;194(5):1295-300 [PMID: 26070893]
  5. Nucleic Acids Res. 2015 Aug 18;43(14):6701-13 [PMID: 26117537]
  6. N Engl J Med. 2015 Feb 26;372(9):793-5 [PMID: 25635347]
  7. Genomics Proteomics Bioinformatics. 2014 Aug;12(4):153-5 [PMID: 25042682]
  8. Biol Direct. 2012 Nov 28;7:43; discussion 43 [PMID: 23190475]
  9. Gynecol Oncol. 2015 Dec;139(3):481-6 [PMID: 26449316]
  10. Nat Rev Endocrinol. 2016 Mar;12(3):177-83 [PMID: 26775764]

Word Cloud

Similar Articles

Cited By