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Case reports in pathology
2019;2019 4084196.

Gastroblastoma in Adulthood-A Rarity among Rare Cancers-A Case Report and Review of the Literature.

Giovanni Centonze, Alessandro Mangogna, Tiziana Salviato, Beatrice Belmonte, Laura Cattaneo, Melissa Anna Teresa Monica, Giovanna Garzone, Cecilia Brambilla, Alessio Pellegrinelli, Flavia Melotti, Adele Testi, Valentina Monti, Ketevani Kankava, Patrizia Gasparini, Gianpaolo Dagrada, Vincenzo Mazzaferro, Christian Cotsoglou, Paola Collini, Giancarlo Pruneri, Massimo Milione
Author Information
  1. Giovanni Centonze: Clinical Research Lab, Department of Pathology and Laboratory Medicine, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy. ORCID
  2. Alessandro Mangogna: Clinical Department of Medical, Surgical and Health Science, University of Trieste, Ospedale di Cattinara, Trieste, Italy. ORCID
  3. Tiziana Salviato: Department of Diagnostic, Clinic and Public Health Medicine, University of Modena and Reggio Emilia, Modena, Italy.
  4. Beatrice Belmonte: Tumor Immunology Unit, Department of Health Sciences, Human Pathology Section, University of Palermo, Palermo, Italy.
  5. Laura Cattaneo: First Pathology Division, Department of Pathology and Laboratory Medicine, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy.
  6. Melissa Anna Teresa Monica: First Pathology Division, Department of Pathology and Laboratory Medicine, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy.
  7. Giovanna Garzone: Clinical Research Lab, Department of Pathology and Laboratory Medicine, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy.
  8. Cecilia Brambilla: Department of Histopathology, Royal Brompton Hospital and Harefield NHS Trust, London, UK.
  9. Alessio Pellegrinelli: First Pathology Division, Department of Pathology and Laboratory Medicine, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy.
  10. Flavia Melotti: Servizio di Anatomia Patologica, Azienda Socio-Sanitaria Territoriale del Garda Presidio di Desenzano, Desenzano del Garda, Brescia, Italy.
  11. Adele Testi: Second Pathology Division, Department of Pathology and Laboratory Medicine, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy.
  12. Valentina Monti: Second Pathology Division, Department of Pathology and Laboratory Medicine, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy.
  13. Ketevani Kankava: First Pathology Division, Department of Pathology and Laboratory Medicine, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy.
  14. Patrizia Gasparini: Tumor Genomics Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  15. Gianpaolo Dagrada: Second Pathology Division, Department of Pathology and Laboratory Medicine, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy.
  16. Vincenzo Mazzaferro: Hepato-Bilio-Pancreatic Surgery and Liver Transplantation, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy.
  17. Christian Cotsoglou: Hepato-Bilio-Pancreatic Surgery and Liver Transplantation, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy.
  18. Paola Collini: Second Pathology Division, Department of Pathology and Laboratory Medicine, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy.
  19. Giancarlo Pruneri: Second Pathology Division, Department of Pathology and Laboratory Medicine, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy.
  20. Massimo Milione: First Pathology Division, Department of Pathology and Laboratory Medicine, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy. ORCID
PMID: 31871808 DOI: 10.1155/2019/4084196

Abstract

Gastroblastoma (GB) is a rare gastric epithelial-mesenchymal neoplasm, first described by Miettinen et al. So far, all reported cases described the tumor in children or young adults, and similarities with other childhood blastomas have been postulated. We report a case of GB in a 43-year-old patient with long follow up and no recurrence up to 100 months after surgery. So far, this is the second case of GB occurring in the adult age >40-year-old. Hence, GB should be considered in the differential diagnosis of microscopically comparable conditions in adults carrying a worse prognosis and different clinical approach.

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