Exhaled breath biomarker sensing.

Alina Vasilescu, Borys Hrinczenko, Greg M Swain, Serban F Peteu
Author Information
  1. Alina Vasilescu: International Centre of Biodynamics, Bucharest, Romania. Electronic address: avasilescu@biodyn.ro.
  2. Borys Hrinczenko: Division of Hematology & Oncology, Breslin Cancer Center, Michigan State University, USA.
  3. Greg M Swain: Department of Chemistry, Michigan State University, USA; Neuroscience Program, Michigan State University, USA.
  4. Serban F Peteu: Department of Chemistry, Michigan State University, USA. Electronic address: peteu@msu.edu.

Abstract

This goal of this minireview is to introduce the reader to the area of research concerned with exhaled breath analysis for the purpose of detecting abnormal levels of physiologically-relevant chemical markers reflective of respiratory diseases. Two main two groups of sensing methods are reviewed: mass spectrometry and (bio)sensors. The discussion focuses on biosensor applications for EB and EBC analyses, which are presented in detail. The review finishes with conclusions and future perspectives, including recommendations for future near-term and long-term development of EBC biomarker sensing.

Keywords

MeSH Term

Biomarkers
Biosensing Techniques
Body Fluids
Breath Tests
Exhalation

Chemicals

Biomarkers

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