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Children (Basel, Switzerland)
05 27, 2021;8 (6):

Bariatric Surgery in Adolescents: To Do or Not to Do?

Valeria Calcaterra, Hellas Cena, Gloria Pelizzo, Debora Porri, Corrado Regalbuto, Federica Vinci, Francesca Destro, Elettra Vestri, Elvira Verduci, Alessandra Bosetti, Gianvincenzo Zuccotti, Fatima Cody Stanford
Author Information
  1. Valeria Calcaterra: Pediatric and Adolescent Unit, Department of Internal Medicine, University of Pavia, 27100 Pavia, Italy. ORCID
  2. Hellas Cena: Clinical Nutrition and Dietetics Service, Unit of Internal Medicine and Endocrinology, ICS Maugeri IRCCS, 27100 Pavia, Italy. ORCID
  3. Gloria Pelizzo: Pediatric Surgery Department, "V. Buzzi" Children's Hospital, 20154 Milan, Italy.
  4. Debora Porri: Clinical Nutrition and Dietetics Service, Unit of Internal Medicine and Endocrinology, ICS Maugeri IRCCS, 27100 Pavia, Italy. ORCID
  5. Corrado Regalbuto: Pediatric Unit, Fond. IRCCS Policlinico S. Matteo and University of Pavia, 27100 Pavia, Italy.
  6. Federica Vinci: Pediatric Unit, Fond. IRCCS Policlinico S. Matteo and University of Pavia, 27100 Pavia, Italy.
  7. Francesca Destro: Pediatric Surgery Department, "V. Buzzi" Children's Hospital, 20154 Milan, Italy.
  8. Elettra Vestri: Pediatric Surgery Department, "V. Buzzi" Children's Hospital, 20154 Milan, Italy.
  9. Elvira Verduci: Pediatric Department, "V. Buzzi" Children's Hospital, 20154 Milan, Italy. ORCID
  10. Alessandra Bosetti: Pediatric Department, "V. Buzzi" Children's Hospital, 20154 Milan, Italy.
  11. Gianvincenzo Zuccotti: Pediatric Department, "V. Buzzi" Children's Hospital, 20154 Milan, Italy. ORCID
  12. Fatima Cody Stanford: Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. ORCID
PMID: 34072065 DOI: 10.3390/children8060453

Abstract

Pediatric obesity is a multifaceted disease that can impact physical and mental health. It is a complex condition that interweaves biological, developmental, environmental, behavioral, and genetic factors. In most cases lifestyle and behavioral modification as well as medical treatment led to poor short-term weight reduction and long-term failure. Thus, bariatric surgery should be considered in adolescents with moderate to severe obesity who have previously participated in lifestyle interventions with unsuccessful outcomes. In particular, laparoscopic sleeve gastrectomy is considered the most commonly performed bariatric surgery worldwide. The procedure is safe and feasible. The efficacy of this weight loss surgical procedure has been demonstrated in pediatric age. Nevertheless, there are barriers at the patient, provider, and health system levels, to be removed. First and foremost, more efforts must be made to prevent decline in nutritional status that is frequent after bariatric surgery, and to avoid inadequate weight loss and weight regain, ensuring successful long-term treatment and allowing healthy growth. In this narrative review, we considered the rationale behind surgical treatment options, outcomes, and clinical indications in adolescents with severe obesity, focusing on LSG, nutritional management, and resolution of metabolic comorbidities.

Keywords

adolescents bariatric surgery complications laparoscopic sleeve gastrectomy multi-disciplinarity nutritional status pediatric obesity weight loss

References

Obes Surg. 2004 May;14(5):644-7 [PMID: 15186632]
Diabetes. 2014 Oct;63(10):3372-7 [PMID: 24848069]
Eur J Nutr. 2015 Aug;54(5):771-82 [PMID: 25129656]
Expert Rev Endocrinol Metab. 2021 May;16(3):123-134 [PMID: 33879013]
Ann Surg. 2008 Mar;247(3):401-7 [PMID: 18376181]
Diabetes. 2011 Feb;60(2):477-85 [PMID: 21228310]
Obes Surg. 2012 May;22(5):740-8 [PMID: 22354457]
Transl Pediatr. 2017 Oct;6(4):397-407 [PMID: 29184820]
Obes Surg. 2018 Jul;28(7):2060-2068 [PMID: 29693218]
Nutrients. 2020 Jan 27;12(2): [PMID: 32012681]
Int J Obes (Lond). 2014 Mar;38(3):334-40 [PMID: 24048144]
Front Immunol. 2017 Jul 28;8:838 [PMID: 28804483]
Int J Obes (Lond). 2021 Jan;45(1):12-24 [PMID: 33208861]
Children (Basel). 2021 Jan 10;8(1): [PMID: 33435250]
Gastroenterology. 2016 Feb;150(2):454-64.e9 [PMID: 26481855]
J Am Coll Cardiol. 2018 Feb 13;71(6):670-687 [PMID: 29420964]
JAMA. 2014 Jun 11;311(22):2297-304 [PMID: 24915261]
J Obes Metab Syndr. 2019 Dec;28(4):216-224 [PMID: 31909364]
Surg Obes Relat Dis. 2019 Jan;15(1):133-144 [PMID: 30514669]
Pediatrics. 2018 Mar;141(3): [PMID: 29483202]
Surg Obes Relat Dis. 2011 Jul-Aug;7(4):510-5 [PMID: 21130052]
Surg Obes Relat Dis. 2012 Jan-Feb;8(1):1-7 [PMID: 22030146]
Obes Surg. 2018 Jul;28(7):2040-2045 [PMID: 29430596]
Springerplus. 2016 Sep 01;5(1):1467 [PMID: 27652042]
Surg Obes Relat Dis. 2020 Oct;16(10):1463-1473 [PMID: 32709580]
Acta Physiol (Oxf). 2011 Apr;201(4):405-11 [PMID: 21392266]
Indian Pediatr. 2019 Apr 15;56(4):317-321 [PMID: 31064903]
Front Pediatr. 2019 Apr 03;7:123 [PMID: 31024868]
Front Endocrinol (Lausanne). 2020 May 13;11:290 [PMID: 32477270]
Curr Treat Options Pediatr. 2020 Jun;6(2):62-77 [PMID: 33457188]
Postgrad Med. 2018 Mar;130(2):173-182 [PMID: 29388462]
J Clin Endocrinol Metab. 2011 Dec;96(12):E1999-2008 [PMID: 21994964]
Int J Obes (Lond). 2011 Jul;35(7):891-8 [PMID: 20975725]
N Engl J Med. 2014 May 22;370(21):2002-13 [PMID: 24679060]
Obes Surg. 2018 Feb;28(2):474-482 [PMID: 28822064]
Eur J Endocrinol. 2017 Apr;176(4):D1-D15 [PMID: 28174231]
JAMA Pediatr. 2013 Feb;167(2):126-32 [PMID: 23247297]
Surg Obes Relat Dis. 2017 Jan;13(1):101-109 [PMID: 27521254]
Am J Clin Nutr. 2007 Jul;86(1):107-15 [PMID: 17616769]
Ann Surg. 2008 Nov;248(5):763-76 [PMID: 18948803]
J Clin Endocrinol Metab. 2010 Dec;95(12):5189-98 [PMID: 20829185]
J Am Assoc Nurse Pract. 2021 Jan 27;33(11):1055-1065 [PMID: 33534281]
Obes Surg. 2013 Aug;23(8):1252-61 [PMID: 23475776]
Surg Obes Relat Dis. 2016 Dec;12(10):1778-1786 [PMID: 27178613]
JAMA. 2010 Feb 10;303(6):519-26 [PMID: 20145228]
Pediatrics. 2011 Dec;128 Suppl 5:S213-56 [PMID: 22084329]
J Am Coll Surg. 2012 Apr;214(4):550-6; discussion 556-7 [PMID: 22321517]
JAMA Pediatr. 2018 Dec 1;172(12):1191-1192 [PMID: 30357351]
J Clin Endocrinol Metab. 2017 Mar 01;102(3):709-757 [PMID: 28359099]
Surg Endosc. 2019 May;33(5):1600-1612 [PMID: 30225604]
Ann N Y Acad Sci. 2018 Oct;1430(1):3-43 [PMID: 30151974]
Hosp Pract (1995). 2014 Apr;42(2):77-88 [PMID: 24769787]
Appetite. 2018 Aug 1;127:349-355 [PMID: 29746881]
Clin Gastroenterol Hepatol. 2020 May;18(5):1070-1081.e5 [PMID: 31706057]
Arq Bras Cir Dig. 2021 Jan 25;33(4):e1553 [PMID: 33503113]
Biomolecules. 2020 Sep 16;10(9): [PMID: 32947869]
Baillieres Clin Endocrinol Metab. 1994 Jan;8(1):111-36 [PMID: 7907860]
Curr Opin Pediatr. 2011 Oct;23(5):552-6 [PMID: 21804384]
Curr Obes Rep. 2017 Sep;6(3):278-285 [PMID: 28815416]
Obes Surg. 2018 Jan;28(1):130-134 [PMID: 28707172]
J Pediatr Gastroenterol Nutr. 2015 Apr;60(4):550-61 [PMID: 25591123]
Pediatrics. 2017 Sep;140(3): [PMID: 28827377]
Pediatrics. 2018 Jan;141(1): [PMID: 29237801]
J Clin Res Pediatr Endocrinol. 2016 Jun 5;8(2):250-6 [PMID: 26757831]
Nutr Clin Pract. 2010 Apr;25(2):175-82 [PMID: 20413698]
Semin Pediatr Surg. 2014 Feb;23(1):1 [PMID: 24491359]
Curr Pediatr Rep. 2020 Jun;8(2):56-65 [PMID: 32632353]
Obes Surg. 2019 Jun;29(6):1851-1857 [PMID: 30790164]
Am J Gastroenterol. 2019 Dec;114(12):1857-1862 [PMID: 31658128]
Endosc Int Open. 2021 Jan;9(1):E87-E95 [PMID: 33403240]
J Dev Orig Health Dis. 2022 Feb;13(1):68-74 [PMID: 33650483]
Obes Rev. 2005 Nov;6(4):307-22 [PMID: 16246216]
Obesity (Silver Spring). 2019 Jun;27(6):989-996 [PMID: 31050388]
Front Pediatr. 2021 Jan 12;8:581461 [PMID: 33511092]
Front Endocrinol (Lausanne). 2020 Mar 24;11:157 [PMID: 32265846]
Eat Disord. 2017 May-Jun;25(3):216-229 [PMID: 28139175]
Surg Obes Relat Dis. 2020 Nov;16(11):1682-1683 [PMID: 32972864]
Curr Opin Clin Nutr Metab Care. 2011 Mar;14(2):151-7 [PMID: 21178608]
J Pediatr Adolesc Gynecol. 2016 Dec;29(6):551-557 [PMID: 27262833]
J Gastrointest Surg. 2012 Jun;16(6):1116-22 [PMID: 22402955]
Circulation. 2004 Oct 19;110(16):2494-7 [PMID: 15477412]
Surg Obes Relat Dis. 2019 Jan;15(1):14-20 [PMID: 30448342]
Obes Surg. 2016 Aug;26(8):1912-7 [PMID: 26729282]
J Physiol Biochem. 2009 Sep;65(3):277-89 [PMID: 20119822]
Surg Obes Relat Dis. 2018 Jul;14(7):943-950 [PMID: 29803410]
Sleep. 2020 Oct 13;43(10): [PMID: 32280981]
Am J Physiol Endocrinol Metab. 2014 Feb 15;306(4):E424-32 [PMID: 24368666]
Surg Obes Relat Dis. 2020 Feb;16(2):254-260 [PMID: 31843455]
Heliyon. 2020 Feb 29;6(2):e03496 [PMID: 32154399]
Arterioscler Thromb Vasc Biol. 2007 Aug;27(8):1803-10 [PMID: 17569881]
J Obes Metab Syndr. 2020 Mar 30;29(1):4-11 [PMID: 32183507]
Child Obes. 2018 Nov/Dec;14(8):510-517 [PMID: 30153037]
Clin Obes. 2015 Jun;5(3):116-26 [PMID: 25974187]
Aliment Pharmacol Ther. 2014 Sep;40(6):582-609 [PMID: 25078533]
Diabetes Care. 2016 Nov;39(11):1996-2003 [PMID: 27733421]
J Am Diet Assoc. 2011 Nov;111(11):1688-95 [PMID: 22027051]
Surg Obes Relat Dis. 2013 May-Jun;9(3):474-80 [PMID: 23391810]
Obes Surg. 2015 May;25(5):860-78 [PMID: 25697125]
Diabetes Care. 2013 Jul;36(7):2062-9 [PMID: 23359363]
Metabolism. 2014 Feb;63(2):242-9 [PMID: 24332707]
Acta Paediatr. 2009 Feb;98(2):346-51 [PMID: 18826492]
JAMA Pediatr. 2018 May 1;172(5):452-460 [PMID: 29532078]
Br J Surg. 2010 Dec;97(12):1838-44 [PMID: 20862711]
Obes Surg. 2014 Jun;24(6):903-8 [PMID: 24566661]
Surg Obes Relat Dis. 2018 May;14(5):545-551 [PMID: 29551470]
Can Fam Physician. 2011 Feb;57(2):195-7 [PMID: 21642717]
Front Pediatr. 2021 Jan 27;8:591598 [PMID: 33585363]
Semin Pediatr Surg. 2020 Feb;29(1):150889 [PMID: 32238284]
Surg Clin North Am. 2021 Apr;101(2):199-212 [PMID: 33743964]
Ann Surg. 2018 Jul;268(1):106-113 [PMID: 28692476]
N Engl J Med. 2016 Jan 14;374(2):113-23 [PMID: 26544725]
Scand J Gastroenterol. 1981;16(6):721-5 [PMID: 7034160]
Int J Obes Relat Metab Disord. 1997 May;21(5):387-92 [PMID: 9152741]
Surg Obes Relat Dis. 2015 Nov-Dec;11(6):1315-22 [PMID: 26003897]
Am J Public Health. 2015 Sep;105(9):e54-9 [PMID: 26180980]
Surg Obes Relat Dis. 2014 Jul-Aug;10(4):589-97 [PMID: 24582411]
Br J Surg. 2014 May;101(6):661-8 [PMID: 24723019]
BMC Public Health. 2021 Apr 29;21(1):824 [PMID: 33926412]
Surg Obes Relat Dis. 2019 Sep;15(9):1494-1502 [PMID: 31371184]
Pediatr Diabetes. 2017 Feb;18(1):59-66 [PMID: 26825860]
Horm Res Paediatr. 2020;93(4):215-225 [PMID: 33017828]
J Pediatr. 2007 Apr;150(4):383-7 [PMID: 17382115]
Br J Nutr. 2012 Mar;107(5):755-64 [PMID: 21846429]
Eur J Pediatr Surg. 2020 Feb;30(1):117-121 [PMID: 32069497]
Cochrane Database Syst Rev. 2015 Jun 24;(6):CD011740 [PMID: 26104326]
Metab Syndr Relat Disord. 2014 Dec;12(10):527-32 [PMID: 25247821]
Ann Surg. 2021 Mar 1;273(3):542-547 [PMID: 30998539]
J Obes Metab Syndr. 2019 Mar;28(1):1-3 [PMID: 31089574]
Pediatrics. 2021 Mar;147(3): [PMID: 33526606]
Gastroenterology. 2015 May;148(6):1219-33 [PMID: 25241326]
Pharmacol Ther. 2009 Oct;124(1):44-56 [PMID: 19560488]
Pediatr Obes. 2019 May;14(5):e12495 [PMID: 30653847]
Gastroenterol Res Pract. 2013;2013:256145 [PMID: 24348530]
Surg Endosc. 2020 Jun;34(6):2332-2358 [PMID: 32328827]
Pediatrics. 2008 Jul;122(1):198-208 [PMID: 18596007]
Am J Clin Nutr. 2008 Mar;87(3):586-92 [PMID: 18326595]
Obesity (Silver Spring). 2015 Mar;23(3):591-601 [PMID: 25707380]
N Engl J Med. 2019 Aug 29;381(9):e17 [PMID: 31461610]
Am J Clin Nutr. 2015 Sep;102(3):540-7 [PMID: 26201818]
J Pediatr (Rio J). 2021 May-Jun;97(3):273-279 [PMID: 33022267]
Obes Surg. 2018 Dec;28(12):3783-3794 [PMID: 30121858]
Arch Pediatr Adolesc Med. 2003 Aug;157(8):821-7 [PMID: 12912790]
World J Gastroenterol. 2008 Apr 21;14(15):2425-9 [PMID: 18416474]
Peptides. 2007 Feb;28(2):459-63 [PMID: 17207558]
Surg Obes Relat Dis. 2018 Jul;14(7):882-901 [PMID: 30077361]
J Gastrointest Surg. 2003 Jan;7(1):102-108 [PMID: 12559191]
Obes Surg. 2021 Feb;31(2):675-681 [PMID: 32827092]
J Thromb Haemost. 2010 Apr;8(4):759-65 [PMID: 20102484]
Surg Obes Relat Dis. 2017 May;13(5):774-778 [PMID: 28256393]
Ann Surg. 2009 Jun;249(6):948-53 [PMID: 19474685]
Nutr Clin Pract. 2017 Aug;32(4):502-507 [PMID: 28760109]
Int J Eat Disord. 2016 Oct;49(10):947-952 [PMID: 27196378]
Surg Obes Relat Dis. 2013 Sep-Oct;9(5):667-77 [PMID: 23466015]
Obes Rev. 2013 Aug;14(8):634-44 [PMID: 23577666]
World J Surg. 2009 May;33(5):972-9 [PMID: 19288284]
Pediatr Obes. 2012 Aug;7(4):284-94 [PMID: 22715120]
Pediatrics. 2018 Feb;141(2): [PMID: 29311357]
J Clin Res Pediatr Endocrinol. 2011;3(2):70-6 [PMID: 21750635]
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