Machine learning algorithms utilizing blood parameters enable early detection of immunethrombotic dysregulation in COVID-19.
Zhaoming Zhou, Xiang Zhou, Liming Cheng, Lei Wen, Taixue An, Heng Gao, Hongrong Deng, Qi Yan, Xinlu Zhang, Youjiang Li, Yixing Liao, Xin-Zu Chen, Bin Nie, Jie Cheng, Guanhua Deng, Shengqiang Wang, Juan Li, Hanqi Yin, Mengxian Zhang, Linbo Cai, Lei Zheng, Minglun Li, Bleddyn Jones, Longhua Chen, Amir Abdollahi, Meijuan Zhou, Ping-Kun Zhou, Cheng Zhou
Author Information
- Zhaoming Zhou: Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China. ORCID
- Xiang Zhou: Department of Anesthesiology, General Hospital of Central Theater Command of PLA, Wuhan, China.
- Liming Cheng: Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
- Lei Wen: Department of Oncology, Guangdong Sanjiu Brain Hospital, Guangzhou, China.
- Taixue An: Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China.
- Heng Gao: Department of Neurosurgery, Jiangyin Affiliated Hospital of Southeast University School of Medicine, Jiangyin, China.
- Hongrong Deng: Department of Endocrinology and Metabolism, Guangdong Provincial Key Laboratory of Diabetology, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
- Qi Yan: Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
- Xinlu Zhang: Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
- Youjiang Li: Department of Clinical Laboratory, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China.
- Yixing Liao: Department of Critical Care Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
- Xin-Zu Chen: Department of Gastrointestinal and Hernia Surgery, The Second People's Hospital of Yibin - West China Yibin Hospital, Sichuan University, Yibin, China.
- Bin Nie: Department of Laboratory Medicine, The Second People's Hospital of Yibin - West China Yibin Hospital, Sichuan University, Yibin, China.
- Jie Cheng: Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
- Guanhua Deng: Department of Oncology, Guangdong Sanjiu Brain Hospital, Guangzhou, China.
- Shengqiang Wang: Department of Rehabilitation Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
- Juan Li: Department of Oncology, Guangdong Sanjiu Brain Hospital, Guangzhou, China.
- Hanqi Yin: South China Institute of Biomedicine, Guangzhou, China.
- Mengxian Zhang: Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
- Linbo Cai: Department of Oncology, Guangdong Sanjiu Brain Hospital, Guangzhou, China.
- Lei Zheng: Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China.
- Minglun Li: Department of Radiation Oncology, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.
- Bleddyn Jones: Gray Laboratory, CRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Oxford, UK.
- Longhua Chen: Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
- Amir Abdollahi: Translational Radiation Oncology, German Cancer Research Center (DKFZ) and University Heidelberg School of Medicine, Heidelberg, Germany.
- Meijuan Zhou: Department of Radiation Medicine, School of Public Health, Southern Medical University, Guangzhou, China.
- Ping-Kun Zhou: Department of Radiation Biology, Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, China.
- Cheng Zhou: Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China. ORCID
No abstract text available.
- JAMA. 2020 Sep 3;:
[PMID: 32880615]
- Blood Rev. 2021 Mar;46:100745
[PMID: 32868115]
- Blood. 2020 Jun 4;135(23):2033-2040
[PMID: 32339221]
- Science. 2020 Sep 4;369(6508):
[PMID: 32669297]
- Nat Commun. 2020 Nov 17;11(1):5859
[PMID: 33203833]
- Sci Transl Med. 2020 Nov 18;12(570):
[PMID: 33139519]
- Lancet Respir Med. 2020 Jun;8(6):e46-e47
[PMID: 32353251]
- Transl Res. 2020 Jun;220:1-13
[PMID: 32299776]
- Cell Mol Immunol. 2020 May;17(5):541-543
[PMID: 32203186]
- Am J Respir Crit Care Med. 2020 May 15;201(10):1294-1297
[PMID: 32200645]
- BMJ Evid Based Med. 2021 Jun;26(3):107-108
[PMID: 32934000]
- J Exp Med. 2012 Apr 9;209(4):819-35
[PMID: 22451716]
- A2020499/Guangdong Medical Research Foundation
- A2020505/Guangdong Medical Research Foundation
- B2021139/Guangdong Medical Research Foundation
- B2021203/Guangdong Medical Research Foundation
- 2019M662974/China Postdoctoral Science Foundation
- 2020T130052ZX/China Postdoctoral Science Foundation
- 81703166/National Natural Science Foundation of China
- 2019A1515011943/Natural Science Foundation of Guangdong Province
- 202002030445/Science and Technology Program of Guangzhou
- 202002030086/Science and Technology Program of Guangzhou
Algorithms
COVID-19
Early Diagnosis
Gene Expression Profiling
Humans
Machine Learning
SARS-CoV-2
Thrombosis