Unusual late-onset hypertrophic pyloric stenosis in an adolescent girl with down syndrome: Case report and review of the literature.

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Annalisa Chiodi, Maria Escolino, Claudia Di Mento, Vincenzo Salvati, Valerio Mazzone, Giorgia Esposito, Mauro Porcaro, Ciro Esposito

Author Information

Annalisa Chiodi: Division of Pediatric Surgery, Federico II University Hospital, Naples, Italy.
Maria Escolino: Division of Pediatric Surgery, Federico II University Hospital, Naples, Italy. ORCID
Claudia Di Mento: Division of Pediatric Surgery, Federico II University Hospital, Naples, Italy.
Vincenzo Salvati: Division of Pediatric Surgery, Federico II University Hospital, Naples, Italy.
Valerio Mazzone: Division of Pediatric Surgery, Federico II University Hospital, Naples, Italy.
Giorgia Esposito: Division of Internal Medicine, Federico II University Hospital, Naples, Italy.
Mauro Porcaro: Division of Pediatric Radiology, Federico II University Hospital, Naples, Italy.
Ciro Esposito: Division of Pediatric Surgery, Federico II University Hospital, Naples, Italy.

PMID: 39096100 DOI: 10.1002/jcu.23777

A 16-year-old girl with down syndrome came to our attention for recurrent postprandial vomiting and significant weight loss (>5��kgs). Diagnostic assessment (barium swallow study, ultrasonography, and CT) confirmed hypertrophic pyloric stenosis (HPS). Initial attempt with endoscopic dilation was not successful. The patient underwent Heineke-Mikulicz pyloroplasty. Full oral feeding was achieved by Day 7 postoperatively. At 6-month follow-up, the patient reported relief of symptoms, normal feeding habits and substantial weight gain. HPS should be considered in the differential diagnosis of recurrent vomiting, regardless of age. A comprehensive diagnostic work-up, including ultrasonography, endoscopy, and CT, is recommended to confirm the diagnosis.

adolescent down syndrome hypertrophic pyloric stenosis pyloroplasty vomiting

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Humans

Female

Pyloric Stenosis, Hypertrophic

Down Syndrome

Adolescent

Diagnosis, Differential

Ultrasonography

Case Reports Journal Article Review

No available data.

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