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Nov 12, 2024;13 (11): e0076824.

Human immunodeficiency virus-1 genome from patient with fever, Nepal.

Eans Tara Tuladhar, Bimal Sharma Chalise, Binod Khadka, Mamta Tamang, Jenish Neupane, Shankar Poudel, Lindsay Droit, Kathie A Mihindukulasuriya, Annie Elong Ngono, Yuba Nidhi Basaula, Sujan Shresta, David Wang, Krishna Das Manandhar
Author Information
  1. Eans Tara Tuladhar: Tribhuvan University Central Department of Biotechnology, Kathmandu, Nepal. ORCID
  2. Bimal Sharma Chalise: Sukraraj Tropical and Infectious Disease Hospital, Kathmandu, Nepal.
  3. Binod Khadka: Tribhuvan University Central Department of Biotechnology, Kathmandu, Nepal.
  4. Mamta Tamang: Tribhuvan University Central Department of Biotechnology, Kathmandu, Nepal.
  5. Jenish Neupane: Sukraraj Tropical and Infectious Disease Hospital, Kathmandu, Nepal.
  6. Shankar Poudel: Sukraraj Tropical and Infectious Disease Hospital, Kathmandu, Nepal.
  7. Lindsay Droit: Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.
  8. Kathie A Mihindukulasuriya: Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.
  9. Annie Elong Ngono: La Jolla Institute for Immunology, La Jolla, California, USA.
  10. Yuba Nidhi Basaula: Sukraraj Tropical and Infectious Disease Hospital, Kathmandu, Nepal.
  11. Sujan Shresta: La Jolla Institute for Immunology, La Jolla, California, USA. ORCID
  12. David Wang: Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA. ORCID
  13. Krishna Das Manandhar: Tribhuvan University Central Department of Biotechnology, Kathmandu, Nepal. ORCID
PMID: 39431871 DOI: 10.1128/mra.00768-24

Abstract

A patient with fever presented to the referral infectious disease hospital in Kathmandu, Nepal. Metagenomic sequencing of the patient's serum recovered a near-complete genome of human immunodeficiency virus-1 (HIV-1), distinct from previous HIV-1 genomes from Nepal in GenBank. It shared 92.48% nucleotide identity with an HIV-1 subtype C isolate from India.

Keywords

HIV WGS fever of unknown origin

References

Mol Syst Biol. 2011 Oct 11;7:539 [PMID: 21988835]
Bioinformatics. 2015 May 15;31(10):1674-6 [PMID: 25609793]
Nat Med. 2015 Oct;21(10):1228-34 [PMID: 26366711]
Nucleic Acids Res. 2021 Jul 2;49(W1):W293-W296 [PMID: 33885785]
Gigascience. 2020 Oct 15;9(10): [PMID: 33057676]
Nucleic Acids Res. 2016 Jul 8;44(W1):W232-5 [PMID: 27084950]
PLoS Biol. 2003 Nov;1(2):E2 [PMID: 14624234]
BMC Bioinformatics. 2019 Jan 23;20(1):48 [PMID: 30674273]

Grants

  1. U01 AI151810/NIAID NIH HHS
  2. 1U01AI151810/HHS | National Institutes of Health (NIH)
Journal Article

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