Multimodal Imaging of Coronary Bifurcation TAP Procedures Utilizing Visible Heart® Methodologies: EBC Recommended Steps and Bailout Procedures.

Goran Stankovic, Stefano Cangemi, Amanda DeVos, Francesco Burzotta, Paul A Iaizzo
Author Information
  1. Goran Stankovic: Department of Cardiology, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
  2. Stefano Cangemi: Interventional Cardiology Unit, S. Antonio Abate Hospital, Erice, Sicily, Italy. ORCID
  3. Amanda DeVos: Visible Heart® Laboratories, Department of Surgery, the Institute for Engineering in Medicine, University of Minnesota, Minneapolis, Minnesota, USA. ORCID
  4. Francesco Burzotta: Department of Cardiovascular Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italia. ORCID
  5. Paul A Iaizzo: Visible Heart® Laboratories, Department of Surgery, the Institute for Engineering in Medicine, University of Minnesota, Minneapolis, Minnesota, USA. ORCID

Abstract

In some cases it is critical to clinically perform coronary bifurcation stenting to minimize the potential risk for restenosis and/or stent thrombosis. The European Bifurcation Club (EBC) has provided guidelines for optimally performing such procedures. Yet, sometimes such procedures do not go as planned, and in some cases bailout procedures are required. Here we utilized Visible Heart® (VH) methodologies and multimodal visualizations to better understand each step for optimally performed T and small protrusion (TAP) procedures, as well as those in which complications occurred. These studies were performed within reanimated swine hearts in which endoscopes, fluoroscopy, and optical coherence tomography (OCT) could readily be used. Additionally, because these procedures were performed in reanimated hearts, one could intentionally cause complications, so to perform bailout procedures. Finally, following these procedures each specimen was micro CT scanned, and high resolution computational models (~40 microns) were reconstructed of the final outcomes.

Keywords

References

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MeSH Term

Tomography, Optical Coherence
Animals
Multimodal Imaging
Coronary Vessels
Predictive Value of Tests
X-Ray Microtomography
Sus scrofa
Models, Animal
Models, Cardiovascular
Coronary Angiography
Stents
Computer Simulation
Percutaneous Coronary Intervention
Angioplasty, Balloon, Coronary
Coronary Artery Disease
Radiography, Interventional
Fluoroscopy

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