Wenming Zhao
Professor
Genome Sequence Archive
Email: zhaowm (AT) big.ac.cn
Tel: +86 (10) 8409-7636
Genome Sequence Archive
Email: zhaowm (AT) big.ac.cn
Tel: +86 (10) 8409-7636
Associate Director of National Genomics Data Center (NGDC), Beijing Institute of Genomics, Chinese Academy of Sciences / China National Center for Bioinformation (CNCB), China, 2020 - Present
Professor, Beijing Institute of Genomics, Chinese Academy of Sciences, China, 2018 - Present
Associate Professor, Beijing Institute of Genomics, Chinese Academy of Sciences, China, 2012 - 2018
Assistant Professor, Beijing Institute of Genomics, Chinese Academy of Sciences, China, 2008 - 2012
M.S. in Computer & Engineering, Beihang University, Beijing, China, 2008
B.S. in Computer Technology & Application, Xi'an Technological University, Xi'an, China, 2001
CAS Key Technology Talent Program, 2015. (中国科学院关键技术人才)
Big data and data visualization
Bioinformatics Databases
Cloud Computing and High Performance Computing
BioProject: a centralized database for archiving and publishing research projects.
BioSample: a database focuses on structured and indexed descriptive information on biological samples.
GSA: a data repository for archiving raw sequence reads.
GSA-Human: a data repository specialized for human genetic related data derived from biomedical researches.
Omix: Open Archive for Miscellaneous Data.
iDog: an integrated resource for domestic dog (Canis lupus familiaris) and wild canids.
iSheep: a dedicated database for Ovis aries.
SorgSD: a comprehensive database of sorghum genomic variations.
ChickenSD: a data container for the variation information of chicken.
BioCloud: an online analysis toolkit for bioinformatics big data.
eGPS Cloud: evolutionary Genotype-Phenotype Systems (eGPS) cloud computing platform.
GenBrowser: SARS-COV-2 genome browser.
HGD: A data portal of homologous genes across multiple species.
MACdb: A Curated Knowledgebase for Metabolic Associations across Human Cancers.
TCOD: Tropical Crops Omics Database.
OBIA: Open Biomedical Imaging Archive.
BioKA: a curated and integrated biomarker knowledgebase for animals
Journal Reviewer: Bioinformatics, Briefings in Bioinformatics, BMC Genomics, Frontiers in Plant Science, Chinese Bulletin of Life Sciences, PLoS ONE
CNCB–NGDC Members and Partners. Database resources of the National Genomics Data Center, China National Center for Bioinformation in 2026. Nucleic Acids Res. 2025 Dec 8:gkaf1172. doi: 10.1093/nar/gkaf1172. Epub ahead of print. PMID: 41359036.
Lei W, Li C, Zhou H, Nie Z, Wang A, Li P, Fan Z, Zhu R, Cheng H, Guo Y, Yue L, Jiang X, Gao R, Sheng Y, Niu H, Bahetibieke T, Zhang W, Zhao W, Xiao J, Chen F. TEDD: a comprehensive database for translation efficiency dynamics. Nucleic Acids Res. 2025 Nov 11:gkaf1125. doi: 10.1093/nar/gkaf1125. Epub ahead of print. PMID: 41217970.
Zhang S, Chen X, Jin E, Wang A, Chen T, Zhang X, Zhu J, Dong L, Sun Y, Yu C, Zhou Y, Fan Z, Chen H, Zhai S, Sun Y, Chen Q, Xiao J, Song S, Zhang Z, Bao Y, Wang Y*, Zhao W*. The GSA Family in 2025: A Broadened Sharing Platform for Multi-omics and Multimodal Data. Genomics Proteomics Bioinformatics. 2025 Sep 22;23(4):qzaf072. doi: 10.1093/gpbjnl/qzaf072.
Duan G, Zhang S, Tang B, Xiao J, Zhang Z, Cui P*, Yu J*, Zhao W*. Lineage-associated Human Divergently-paired Genes Exhibit Structural and Regulatory Characteristics. Genomics Proteomics Bioinformatics. 2025 Sep 22;23(4):qzaf058. doi: 10.1093/gpbjnl/qzaf058.
Wang Z, Zhang Z, Zhao D, Du Z, Tang B, Jin E, Kang H, Zhao W*, Meng Y*. TCR and BCR repertoire analysis reveals distinct signatures between benign and malignant ovarian tumors. Front Oncol. 2025 Aug 11;15:1630707. doi: 10.3389/fonc.2025.1630707. PMID: 40860831; PMCID: PMC12375485.
唐碧霞; 王钇博; 张思思; 张陌尘; 康海龙; 王彦青; 陈梅丽; 田东梅; 徐添翼; 李茹姣; 郝丽丽; 肖景发; 宋述慧; 章张; 鲍一明; 赵文明, 生物多样性保护的多组学数据资源进展——以国家基因组科学数据中心为例, 科技导报（北京）, 2025, 43(13).
Ma Y, Zhao X, Jia Y, Han Z, Yu C, Fan Z, Zhang Z, Xiao J, Zhao W, Bao Y, Chen M. The Updated Genome Warehouse: Enhancing Data Value, Security, and Usability to Address Data Expansion. Genomics Proteomics Bioinformatics. 2025 May 10;23(1):qzaf010. doi: 10.1093/gpbjnl/qzaf010. PMID: 39977364; PMCID: PMC12221864.
CNCB-NGDC Members and Partners. Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2025. Nucleic Acids Res. 2025 Jan 6;53(D1):D30-D44. doi: 10.1093/nar/gkae978. PMID: 39530327; PMCID: PMC11701749.
Cui Y, Tang B, Wu G, Li L, Zhang X, Du Z, Zhao W. Classification of Dog Breeds Using Convolutional Neural Network Models and Support Vector Machine. Bioengineering (Basel). 2024 Nov 17;11(11):1157. doi: 10.3390/bioengineering11111157. PMID: 39593817; PMCID: PMC11591900.
Liu Y, Wang Y, Sun J, Kong D, Zhou B, Ding M, Meng Y, Duan G, Cui Y, Fan Z, Zhang YP, Zhao W*, Tang B*. iDog: a multi-omics resource for canids study. Nucleic Acids Res. 2024 Nov 11:gkae1031. doi: 10.1093/nar/gkae1031.
Bu C, Zheng X, Zhao X, Xu T, Bai X, Jia Y, Chen M, Hao L, Xiao J, Zhang Z, Zhao W, Tang B, Bao Y. GenBase: A Nucleotide Sequence Database. Genomics Proteomics Bioinformatics. 2024 Sep 13;22(3):qzae047. doi: 10.1093/gpbjnl/qzae047. PMID: 38913867; PMCID: PMC11434157.
Shi W, Jin E, Fang L, Sun Y, Fan Z, Zhu J, Liang C, Zhang YP, Zhang YQ*, Wang GD*, Zhao W*. VDGE: a data repository of variation database for gene-edited animals across multiple species. Nucleic Acids Res. 2024 Oct 29:gkae956. doi: 10.1093/nar/gkae956.
Wu G, Jin E, Sun Y, Tang B, Zhao W. Deep Attention Fusion Hashing (DAFH) Model for Medical Image Retrieval. Bioengineering. 2024; 11(7):673. https://doi.org/10.3390/bioengineering11070673
Li L, Li C, Li N, Zou D, Zhao W, Luo H, Xue Y, Zhang Z, Bao Y, Song S. Machine Learning Early Detection of SARS-CoV-2 High-Risk Variants. Adv Sci (Weinh). 2024 Dec;11(45):e2405058. doi: 10.1002/advs.202405058. Epub 2024 Oct 14. PMID: 39401400; PMCID: PMC11615786.
Jiang Y, Kang H, Dou H, Guo D, Yuan Q, Dong L, Du Z, Zhao W*, Xin D*. Comparative genomic sequencing to characterize Mycoplasma pneumoniae genome, typing, and drug resistance. Microbiol Spectr. 2024 Aug 6;12(8):e0361523. doi: 10.1128/spectrum.03615-23. Epub 2024 Jun 21. PMID: 38904371; PMCID: PMC11302288.
CNCB-NGDC Members and Partners. Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2024. Nucleic Acids Res. 2024 Jan 5;52(D1):D18-D32. doi: 10.1093/nar/gkad1078. PMID: 38018256; PMCID: PMC10767964.
Wang Y, Lin Y, Wu S, Sun J, Meng Y, Jin E, Kong D, Duan G, Bei S, Fan Z, Wu G, Hao L, Song S, Tang B, Zhao W. BioKA: a curated and integrated biomarker knowledgebase for animals. Nucleic Acids Res. 2023 Oct 16:gkad873. doi: 10.1093/nar/gkad873. Epub ahead of print. PMID: 37843156.
Kang H, Huang T, Duan G, Meng Y, Chen X, He S, Xia Z, Zhou X, Chao J, Tang B, Wang Z, Zhu J, Du Z, Sun Y, Zhang S, Xiao J, Tian W, Wang W, Zhao W. TCOD: an integrated resource for tropical crops. Nucleic Acids Res. 2023 Oct 16:gkad870. doi: 10.1093/nar/gkad870. Epub ahead of print. PMID: 37843152.
Jin E, Zhao D, Wu G, Zhu J, Wang Z, Wei Z, Zhang S, Wang A, Tang B, Chen X, Sun Y, Zhang Z, Zhao W, Meng Y. OBIA: An Open Biomedical Imaging Archive. Genomics Proteomics Bioinformatics. 2023 Oct 6:S1672-0229(23)00108-0. doi: 10.1016/j.gpb.2023.09.003. Epub ahead of print. PMID: 37806555.
Sun Y, Zheng X, Wang G, Wang Y, Chen X, Sun J, Xiong Z, Zhang S, Wang T, Fan Z, Bu C, Bao Y, Zhao W. MACdb: A Curated Knowledgebase for Metabolic Associations across Human Cancers. Mol Cancer Res. 2023 Jul 5;21(7):691-697. doi: 10.1158/1541-7786.MCR-22-0909. PMID: 37027007; PMCID: PMC10320464.
CNCB-NGDC Members & Partners: Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2023. Nucleic Acids Res 2023, 51(D1):D18-D28.
Ma L, Zou D, Liu L, Shireen H, Abbasi AA, Bateman A, Xiao J, Zhao W, Bao Y, Zhang Z: Database Commons: A Catalog of Worldwide Biological Databases. Genomics Proteomics Bioinformatics 2023, epub
Duan G, Wu G, Chen X, Tian D, Li Z, Sun Y, Du Z, Hao L, Song S, Gao Y, Xiao J, Zhang Z, Bao Y, Tang B, Zhao W*. HGD: an integrated homologous gene database across multiple species. Nucleic Acids Res. 2022 Nov 1:gkac970. doi: 10.1093/nar/gkac970. Epub ahead of print. PMID: 36318261.
Yu D, Zhu J, Yang J, Pan YH, Mu H, Cao R, Tang B, Duan G, Hao ZQ, Dai L, Zhao GP, Zhang YP, Zhao W*, Zhang G*, Li H*. Global cold-chain related SARS-CoV-2 transmission identified by pandemic-scale phylogenomics. Zool Res. 2022 Sep 18;43(5):871-874. doi: 10.24272/j.issn.2095-8137.2022.238. PMID: 36031769; PMCID: PMC9486523.
李茹姣, 张欣, 宋述慧, 王彦青, 邹东, 肖景发, 赵文明, 章张, 鲍一明: 基因组科学数据的安全管理与应用. 大数据 2022, 8(1):37-45.
Hou Y, Zhao S, Liu Q, Zhang X, Sha T, Su Y, Zhao W, Bao Y, Xue Y, Chen H. Ongoing Positive Selection Drives the Evolution of SARS-CoV-2 Genomes. Genomics Proteomics Bioinformatics. 2022 Dec;20(6):1214-1223. doi: 10.1016/j.gpb.2022.05.009. Epub 2022 Jun 26. PMID: 35760317; PMCID: PMC9233880.
Zhao D, Zhang Z, Wang Z, Du Z, Wu M, Zhang T, Zhou J, Zhao W*, Meng Y*. Diagnosis and Prediction of Endometrial Carcinoma Using Machine Learning and Artificial Neural Networks Based on Public Databases. Genes (Basel). 2022 May 24;13(6):935. doi: 10.3390/genes13060935. PMID: 35741697; PMCID: PMC9222484.
Yu D, Yang X, Tang B, Pan YH, Yang J, Duan G, Zhu J, Hao ZQ, Mu H, Dai L, Hu W, Zhang M, Cui Y, Jin T, Li CP, Ma L; Language translation team, Su X, Zhang G, Zhao W*, Li H*. Coronavirus GenBrowser for monitoring the transmission and evolution of SARS-CoV-2. Brief Bioinform. 2022 Jan 19:bbab583. doi: 10.1093/bib/bbab583. Epub ahead of print. PMID: 35043153.
CNCB-NGDC Members & Partners: Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2022. Nucleic Acids Res 2022, 50(D1):D27-D38.
Zhang Y, Zou D, Zhu T, Xu T, Chen M, Niu G, Zong W, Pan R, Jing W, Sang J, Liu C, Xiong Y, Sun Y, Zhai S, Chen H, Zhao W, Xiao J, Bao Y, Hao L, Zhang Z: Gene Expression Nebulas (GEN): a comprehensive data portal integrating transcriptomic profiles across multiple species at both bulk and single-cell levels. Nucleic Acids Res 2022, 50(D1):D1016-D1024.
Liu Q, Du Z, Zhu S, Zhao W, Chen H, Xue Y. Metagenomic evidence for the co-existence of SARS and H1N1 in patients from 2007-2012 flu seasons in France. Biosaf Health. 2021 Nov 9. doi: 10.1016/j.bsheal.2021.11.002. Epub ahead of print. PMID: 34778742; PMCID: PMC8577621.
Zhang S, Zhu J, Tang B, Chen H, Xiao J, Zhang Z, Bao Y, Wang Y, Zhao W. GSA-Human: Genome Sequence Archive for Human[J]. 2021. Hereditas(Beijing), doi: 10.16288/j.yczz.21-248.
Chen T, Chen X, Zhang S, Zhu J, Tang B, Wang A, Dong L, Zhang Z, Yu C, Sun Y, Chi L, Chen H, Zhai S, Sun Y, Lan L, Zhang X, Xiao J, Bao Y, Wang Y, Zhang Z, Zhao W. The Genome Sequence Archive Family: Toward Explosive Data Growth and Diverse Data Types. Genomics Proteomics Bioinformatics. 2021 Aug 13:S1672-0229(21)00163-7. doi: 10.1016/j.gpb.2021.08.001. Epub ahead of print. PMID: 34400360.
Wang ZH, Zhu QH, Li X, Zhu JW, Tian DM, Zhang SS, Kang HL, Li CP, Dong LL, Zhao WM*, Li MH*. iSheep: an Integrated Resource for Sheep Genome, Variant and Phenotype. Front Genet. 2021 Aug 17;12:714852. doi: 10.3389/fgene.2021.714852. PMID: 34490043; PMCID: PMC8418083.
Liu Y, Wang Z, Wu X, Zhu J, Luo H, Tian D, Li C, Luo J, Zhao W*, Hao H*, Jing HC. SorGSD: updating and expanding the sorghum genome science database with new contents and tools. Biotechnol Biofuels. 2021 Aug 3;14(1):165. doi: 10.1186/s13068-021-02016-7. PMID: 34344425; PMCID: PMC8336335.
Song S, Ma L, Zou D, Tian D, Li C, Zhu J, Chen M, Wang A, Ma Y, Li M, Teng X, Cui Y, Duan G, Zhang M, Jin T, Shi C, Du Z, Zhang Y, Liu C, Li R, Zeng J, Hao L, Jiang S, Chen H, Han D, Xiao J, Zhang Z*, Zhao W*, Xue Y*, Bao Y*. The Global Landscape of SARS-CoV-2 Genomes, Variants, and Haplotypes in 2019nCoVR. Genomics Proteomics Bioinformatics. 2020 Dec 28:S1672-0229(20)30131-5. doi: 10.1016/j.gpb.2020.09.001. PMID: 33704069.
Wang K, Wang J, Zhu C, Yang L, Ren Y, Ruan J, Fan G, Hu J, Xu W, Bi X, Zhu Y, Song Y, Chen H, Ma T, Zhao R, Jiang H, Zhang B, Feng C, Yuan Y, Gan X, Li Y, Zeng H, Liu Q, Zhang Y, Shao F, Hao S, Zhang H, Xu X, Liu X, Wang D, Zhu M, Zhang G*, Zhao W*, Qiu Q*, He S*, Wang W*. African lungfish genome sheds light on the vertebrate water-to-land transition. Cell. 2021 Mar 4;184(5):1362-1376.e18. doi: 10.1016/j.cell.2021.01.047. PMID: 33545087.
Xue Y*, Bao Y*, Zhang Z*, Zhao W*, Xiao J*, He S*, Zhang G*, Li Y*, Zhao G*, Chen R*, in CNCB-NGDC Members and Partners, Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2021. Nucleic Acids Res. 2021, 49: D18-D28.
Li C, Tian D, Tang B, Liu X, Teng X, Zhao W, Zhang Z, Song S: Genome Variation Map: a worldwide collection of genome variations across multiple species. Nucleic Acids Res 2021, 49(D1):D1186-D1191. [PMID=33170268]
Gong Z, Zhu J, Li C, Jiang S, Ma L, Tang B, Zou D, Chen M, Sun Y, Song S, Zhang Z, Xiao J, Xue Y, Bao Y, Du Z*, Zhao W*, An online coronavirus analysis platform from the National Genomics Data Center, Zoological Research. 2020, 41(6): 705-708.
Liu Q, Zhao S, Shi CM, Song S, Zhu S, Su Y, Zhao W, Li M, Bao Y, Xue Y, Chen H. Population Genetics of SARS-CoV-2: Disentangling Effects of Sampling Bias and Infection Clusters. Genomics Proteomics Bioinformatics. 2020 Dec;18(6):640-647. doi: 10.1016/j.gpb.2020.06.001. Epub 2020 Jul 12. PMID: 32663617; PMCID: PMC7354277.
Liu Q, Zhao S, Shi CM, Song S, Zhu S, Su Y, Zhao W, Li M, Bao Y, Xue Y, Chen H. Population Genetics of SARS-CoV-2: Disentangling Effects of Sampling Bias and Infection Clusters. Genomics Proteomics Bioinformatics. 2020 Jul 12:S1672-0229(20)30062-0. doi: 10.1016/j.gpb.2020.06.001. PMID: 32663617.
Zhang Z*, Song S, Yu J, Zhao W, Xiao J, Bao Y, The Elements of Data Sharing. Genomics, Proteomics & Bioinformatics. 2020, 18:1-4.
Zhao WM*, Song SH*, Chen ML*, Zou D*, Ma LN*, Ma YK, Li RJ, Hao LL, Li CP, Tian DM, Tang BX, Wang YQ, Zhu JW, Chen HX, Zhang Z, Xue YB, Bao YM: The 2019 novel coronavirus resource. Yi Chuan 2020, 42(2):212-221. [PMID=32102777]
Zhang Z*, Zhao W*, Xiao J*, Bao Y*, He S*, Zhang G*, Li Y*, Zhao G*, Chen R*, in National Genomics Data Center Members and Partners, Database Resources of the National Genomics Data Center in 2020. Nucleic Acids Res. 2020, 48: D24-D33.
Yu D, Dong L, Yan F, Mu H, Tang B, Yang X, Zeng T, Zhou Q, Gao F, Wang Z, Hao Z, Kang H, Zheng Y, Huang H, Wei Y, Pan W, Xu Y, Zhu J, Zhao S, Wang C, Wang P, Dai L, Li M, Lan L, Wang Y, Chen H, Li YX, Fu YX, Shao Z, Bao Y, Zhao F, Chen LN, Zhang GQ*, Zhao W*, Li H*. eGPS 1.0: comprehensive software for multi-omic and evolutionary analyses. Natl Sci Rev. 2019 Oct;6(5):867-869. doi: 10.1093/nsr/nwz079.
Wang GD, Shao XJ, Bai B, Wang J, Wang X, Cao X, Liu YH, Wang X, Yin TT, Zhang SJ, Lu Y, Wang Z, Wang L, Zhao W, Zhang B, Ruan J, Zhang YP. Structural variation during dog domestication: insights from gray wolf and dhole genomes. Natl Sci Rev. 2019 Jan;6(1):110-122. doi: 10.1093/nsr/nwy076. Epub 2018 Jul 19. PMID: 34694297; PMCID: PMC8291444.
Zhao Y, Wang J, Liang F, Liu Y, Wang Q, Zhang H, Jiang M, Zhang Z, Zhao W, Bao Y, Zhang Z, Wu J, Asmann Y*, Li R*, Xiao J*, NucMap: a database of genome-wide nucleosome positioning map across species. Nucleic Acids Res. 2019, 47: D163-D169.
Zhang Z*, Zhao W*, Xiao J*, Bao Y*, in BIG Data Center Members, Database Resources of the BIG Data Center in 2019. Nucleic Acids Res. 2019, 47: D8-D14.
Tang B, Zhou Q, Dong L, Li W, Zhang X, Lan L, Zhai S, Xiao J, Zhang Z, Bao Y, Zhang Y, Wang G*, Zhao W*, iDog: an integrated resource for domestic dogs and wild canids. Nucleic Acids Res. 2019, 47: D793-D800.
Tang B, Li F, Li J, Zhao W*, Zhang Z*. Delta: a new web-based 3D genome visualization and analysis platform. Bioinformatics. 2018 Apr 15;34(8):1409-1410. doi: 10.1093/bioinformatics/btx805. PMID: 29253110.
Li R, Liang F, Li W, Zou D, Sun S, Zhao Y, Zhao W, Bao Y, Xiao J, Zhang Z, MethBank 3.0: a database of DNA methylomes across a variety of species. Nucleic Acids Res. 2018, 46: D288-D295.
Zhang SS, Chen TT, Zhu JW, Zhou Q, Chen X, Wang YQ, Zhao WM. GSA: Genome Sequence Archive. Yi Chuan. 2018 Nov 20;40(11):1044-1047. Chinese. doi: 10.16288/j.yczz.18-178. PMID: 30465538.
Song S, Tian D, Li C, Tang B, Dong L, Xiao J, Bao Y, Zhao W, He H, Zhang Z, Genome Variation Map: a data repository of genome variations in BIG Data Center. Nucleic Acids Res. 2018, 46: D121-D126.
Zhang Z*, Zhao W*, Xiao J*, Bao Y*, in BIG Data Center Members, Database Resources of the BIG Data Center in 2018. Nucleic Acids Res. 2018, 46: D14-D20.
Sang J, Wang Z, Li M, Cao J, Niu G, Xia L, Zou D, Wang F, Xu X, Han X, Fan J, Yang Y, Zuo W, Zhang Y, Zhao W, Bao Y, Xiao J, Hu S, Hao L, Zhang Z, ICG: a wiki-driven knowledgebase of internal control genes for RT-qPCR normalization. Nucleic Acids Res. 2018, 46: D121-D126.
Zhang Z*, Zhao W*, Xiao J*, et al. The BIG Data Center: from deposition to integration to translation. Nucleic Acids Research. 2017, 45, D18-D24.
Wang Y, Song F, Zhu J, Zhang S, Yang Y, Chen T, Tang B, Dong L, Ding N, Zhang Q, Bai Z, Dong X, Chen H, Sun M, Zhai S, Sun Y, Yu L, Lan L, Xiao J, Fang X, Lei H, Zhang Z, Zhao W. GSA: Genome Sequence Archive. Genomics, Proteomics & Bioinformatics. 2017, 15:14-18.
Luo H*, Zhao W*, Wang Y*, Xia Y, Wu X, Zhang L, Tang B, Zhu J, Fang L, Du Z, Bekele WA, Tai S, Jordan DR, Godwin ID, Snowdon RJ, Mace ES, Jing HC, Luo J: SorGSD: a sorghum genome SNP database. Biotechnol Biofuels 2016, 9:6. [PMID=26744602]
Zhao W, Zhang S, Tang B, Chen T, Hao L, Sang J, Li R, Xiao J, Zhang Z. Constructing the international database management system for omics big data[J]. Big Data Research, 2016, 2(6): 2016065-.
Ling S, Hu Z, Yang Z, Yang F, Li Y, Lin P, Chen K, Dong L, Cao L, Tao Y, Hao L, Chen Q, Gong Q, Wu D, Li W, Zhao W, Tian X, Hao C, Hungate EA, Catenacci DV, Hudson RR, Li WH, Lu X, Wu CI. Extremely high genetic diversity in a single tumor points to prevalence of non-Darwinian cell evolution. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6496-505. doi: 10.1073/pnas.1519556112. Epub 2015 Nov 11. PMID: 26561581.
Bai B*, Zhao WM*, Tang BX*, Wang YQ, Wang L, Zhang Z, Yang HC, Liu YH, Zhu JW, Irwin DM, Wang GD, Zhang YP:. DoGSD: the dog and wolf genome SNP database. Nucleic Acids Research 2015, 43(D1):D777-D783. [PMID=25404132]
Tang B, Wang Y, Zhu J, Zhao W. Web resources for model organism studies. Genomics, proteomics & bioinformatics 2015, 13(1):64-68. [PMID=25707592]
Ding J, Zhao L, Chang Y, Zhao W, Du Z, Hao Z. Transcriptome sequencing and characterization of Japanese scallop Patinopecten yessoensis from different shell color lines. PLoS One 2015,10(2):e0116406. [PMID=25680107]
Li B, Zong Y, Du Z, Chen Y, Zhang Z, Qin G, Zhao W, Tian S. Genomic characterization reveals insights into patulin biosynthesis and pathogenicity in Penicillium species.Mol Plant Microbe Interact 2015,28(6):635-47. [PMID=25625822]
Di R, He J, Song S, Tian D, Liu Q, Liang X, Ma Q, Sun M, Wang J, Zhao W, Cao G, Wang J, Yang Z, Ge Y, Chu M. Characterization and comparative profiling of ovarian microRNAs during ovine anestrus and the breeding season. BMC Genomics 2014,15:899. [PMID=25318541]
Liang F, Tang B, Wang Y, Wang J, Yu C, Chen X, Zhu J, Yan J, Zhao W*, Li R*. WBSA: web service for bisulfite sequencing data analysis. PloS one 2014, 9(1):e86707.[PMID=24497972]
Wang GD, Zhai W, Yang HC, Fan RX, Cao X, Zhong L, Wang L, Liu F, Wu H, Cheng LG, Poyarkov AD, Poyarkov NA Jr, Tang SS, Zhao WM, Gao Y, Lv XM, Irwin DM, Savolainen P, Wu CI, Zhang YP. The genomics of selection in dogs and the parallel evolution between dogs and humans. Nature Communications 2013,4:1860. [PMID=23673645]
Zheng G, Dahl JA, Niu Y, Fedorcsak P, Huang CM, Li CJ, Vågbø CB, Shi Y, Wang WL, Song SH, Lu Z, Bosmans RP, Dai Q, Hao YJ, Yang X, Zhao WM, Tong WM, Wang XJ, Bogdan F, Furu K, Fu Y, Jia G, Zhao X, Liu J, Krokan HE, Klungland A, Yang YG, He C. ALKBH5 is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility.Molecular Cell 2013,49(1):18-29. [PMID=23177736]
Zhao W, Liu W, Tian D, Tang B, Wang Y, Yu C, Li R, Ling Y, Wu J, Song S, Hu S. wapRNA: a web-based application for the processing of RNA sequences. Bioinformatics 2011, 27(21):3076-3077. [PMID=21896507]
Tao Y, Ruan J, Yeh SH, Lu X, Wang Y, Zhai W, Cai J, Ling S, Gong Q, Chong Z, Qu Z, Li Q, Liu J, Yang J, Zheng C, Zeng C, Wang HY, Zhang J, Wang SH, Hao L, Dong L, Li W, Sun M, Zou W, Yu C, Li C, Liu G, Jiang L, Xu J, Huang H, Li C, Mi S, Zhang B, Chen B, Zhao W, Hu S, Zhuang SM, Shen Y, Shi S, Brown C, White KP, Chen DS, Chen PJ, Wu CI. Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data. Proc Natl Acad Sci U S A2011,108(29):12042-7. [PMID=21730188]
Zhou R*, Ling S*, Zhao W*, Osada N, Chen S, Zhang M, He Z, Bao H, Zhong C, Zhang B, Lu X, Turissini D, Duke NC, Lu J, Shi S, Wu CI. Population genetics in nonmodel organisms: II. natural selection in marginal habitats revealed by deep sequencing on dual platforms. Mol Biol Evol 2011,28(10):2833-42. [PMID=21504891]
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