File:800px-Nuclear receptor action.png
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800px-Nuclear_receptor_action.png (800 × 480 pixels, file size: 314 KB, MIME type: image/png)
This figure depicts the mechanism of a class I nuclear receptor (NR) which, in the absence of ligand, is located in the cytosol. Hormone binding triggers dissociation of heat shock proteins (HSP), dimerization, and translocation to the nucleus where it binds to a specific sequence of DNA known as a hormone response element (HRE). The nuclear receptor DNA complex in turn recruits other proteins that are responsible for translation of downstream DNA into RNA and eventually protein which results in a change in cell function
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 07:44, 8 June 2014 | | 800 × 480 (314 KB) | Zhishp (talk | contribs) | This figure depicts the mechanism of a class I nuclear receptor (NR) which, in the absence of ligand, is located in the cytosol. Hormone binding triggers dissociation of heat shock proteins (HSP), dimerization, and translocation to the nucleus where it bi |
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