Os02g0100100 - Revision history

192.168.72.52 at 06:23, 14 May 2015

2015-05-14T06:23:27Z

Oczhangningning: /* Evolution */

2014-06-08T08:50:21Z

‎Evolution

Oczhangningning: /* Evolution */

2014-06-08T08:41:48Z

‎Evolution

Oczhangningning: /* Evolution */

2014-06-08T08:40:27Z

‎Evolution

Oczhangningning: /* References */

2014-06-08T07:47:02Z

‎References

Oczhangningning: /* References */

2014-06-08T07:45:44Z

‎References

Oczhangningning: /* Expression */

2014-06-08T07:39:04Z

‎Expression

Oczhangningning: /* Expression */

2014-06-08T07:37:51Z

‎Expression

Oczhangningning: /* Protein folding */

2014-06-08T06:57:10Z

‎Protein folding

Oczhangningning: /* Protein folding */

2014-06-08T06:55:46Z

‎Protein folding

@@ Line 19: / Line 19: @@
 The typical PDI is the most prominent member of a family of related PDI-like proteins characterised by the presence of one to three thioredoxin-like active domains<ref name="ref8" />. Several genes encoding PDI-like proteins with unusual primary structure, different expression pattern and exhibiting a wide range of activities have been identified in every extensively sequenced mammalian genome<ref name="ref9" />. Even though all proteins of the PDI family have been located within the ER, where they perform their function, Turano et al. have located some of them in different subcellular locations, but their export mechanism is still unknown. In higher plants, 13 genes have been identified in Arabidopsis (Arabidopsis thaliana) and 12 in rice (Oryza sativa) and in maize (Zea mays) <ref name="ref10" />.
-===Evolution===
+==Structured Information==
-[[File:Phylogenetic tree showing the relationships between the deduced amino acid sequences of PDI and PDI-like genes of different plant species..jpg]]
+     [[Category:Genes]][[Category:Oryza Sativa Japonica Group]][[Category:Japonica Chromosome 2]]
 ==Labs working on this gene==

@@ Line 20: / Line 20: @@
 ===Evolution===
-[[File:Phylogenetic tree showing the relationships between the deduced amino acid sequences of PDI and PDI-like genes of different plant species..jpg|200px|thumb|left|alt text]]
+[[File:Phylogenetic tree showing the relationships between the deduced amino acid sequences of PDI and PDI-like genes of different plant species..jpg]]
 ==Labs working on this gene==

@@ Line 20: / Line 20: @@
 ===Evolution===
-[[File:Phylogenetic tree showing the relationships between the deduced amino acid sequences of PDI and PDI-like genes of different
+[[File:Phylogenetic tree showing the relationships between the deduced amino acid sequences of PDI and PDI-like genes of different plant species..jpg|200px|thumb|left|alt text]]
 ==Labs working on this gene==

@@ Line 20: / Line 20: @@
 ===Evolution===
-Please input evolution information here.
+[[File:Phylogenetic tree showing the relationships between the deduced amino acid sequences of PDI and PDI-like genes of different
+plant species.jpg|200px|thumb|left|alt text]]
 ==Labs working on this gene==

@@ Line 38: / Line 38: @@
 <ref name="ref8">Ellgaard L, Ruddock LW: The human protein disulphide isomerase family: substrate interactions and functional properties. EMBO Rep 2005, 6:28-32.</ref>
 <ref name="ref9">Turano C, Coppari S, Altieri F, Ferraro A: Proteins of the PDI family: unpredicted non-ER locations and functions. J Cell Physiol 2002,193:154-163.</ref>
-<ref name="ref10"></ref>
+<ref name="ref10">Houston NL, Fan C, Xiang QY, Schulze JM, Jung R, Boston RS: Phylogenetic analyses identify 10 classes of the protein disulfide isomerase family in
 </references>

@@ Line 17: / Line 17: @@
 ===Expression===
-The typical PDI is the most prominent member of a family of related PDI-like proteins characterised by the presence of one to three thioredoxin-like active domains[7]. Several genes encoding PDI-like proteins with unusual primary structure, different expression pattern and exhibiting a wide range of activities have been identified in every extensively sequenced mammalian genome[8]. Even though all proteins of the PDI family have been located within the ER, where they perform their function, Turano et al. have located some of them in different subcellular locations, but their export mechanism is still unknown. In higher plants, 13 genes have been identified in Arabidopsis (Arabidopsis thaliana) and 12 in rice (Oryza sativa) and in maize (Zea mays) [9].
+The typical PDI is the most prominent member of a family of related PDI-like proteins characterised by the presence of one to three thioredoxin-like active domains<ref name="ref8" />. Several genes encoding PDI-like proteins with unusual primary structure, different expression pattern and exhibiting a wide range of activities have been identified in every extensively sequenced mammalian genome<ref name="ref9" />. Even though all proteins of the PDI family have been located within the ER, where they perform their function, Turano et al. have located some of them in different subcellular locations, but their export mechanism is still unknown. In higher plants, 13 genes have been identified in Arabidopsis (Arabidopsis thaliana) and 12 in rice (Oryza sativa) and in maize (Zea mays) <ref name="ref10" />.
 ===Evolution===

@@ Line 6: / Line 6: @@
 Please input function information here.
 ====Protein folding====
- PDI contains four thioredoxin-like domains, two of which retain the canonical CXXC motif. The reduced (that is, dithiol) form of PDI is able to catalyse a
+PDI contains four thioredoxin-like domains, two of which retain the canonical CXXC motif. The reduced (that is, dithiol) form of PDI is able to catalyse a reduction of mispaired thiol residues of a particular substrate, acting as an isomerase.<ref name="ref4" /> Therefore, PDI is capable of catalyzing the posttranslational modification disulfide exchange. Such exchange reactions can occur intramolecularly, leading to the rearrangement of disulfide bonds in a single protein.<ref name="ref5" />
 ====Redox signaling====