Os07g0508500 - Revision history

Xysj1985: /* Annotated Information */

2016-10-17T15:50:05Z

‎Annotated Information

Xysj1985 at 15:49, 17 October 2016

2016-10-17T15:49:55Z

Xysj2012 at 08:43, 12 June 2015

2015-06-12T08:43:31Z

Yugee: Blanked the page

2014-06-02T03:19:40Z

Blanked the page

Yugee at 03:13, 2 June 2014

2014-06-02T03:13:58Z

Yugee: Undo revision 175908 by Yugee (talk)

2014-06-02T03:10:42Z

Undo revision 175908 by Yugee (talk)

Yugee: Undo revision 175909 by Yugee (talk)

2014-06-02T03:10:22Z

Undo revision 175909 by Yugee (talk)

Yugee: /* Function */

2014-06-02T03:07:30Z

‎Function

Yugee: /* Function */

2014-06-02T03:06:56Z

‎Function

Yugee: /* Function */

2014-06-02T03:06:27Z

‎Function

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 ==Annotated Information==
-[[File:108-Os07g0508500.png|right|thumb|427px|'''Figure 2.''' ''Meiotic Chromosome Behavior in the Wild Type and brk1-1 Mutant.<ref name="ref1" />.'']]
+[[File:108-Os07g0508500.png|right|thumb|327px|'''Figure 2.''' ''Meiotic Chromosome Behavior in the Wild Type and brk1-1 Mutant.<ref name="ref1" />.'']]
 ===Gene Symbol===
 *'''''Os07g0508500''''' '''''<=>''''' '''''BRK1,OsBRK1'''''

@@ Line 1: / Line 1: @@
-Please input one-sentence summary here.
+The rice '''''Os07g0508500''''' was reported as '''''BRK1''''' in 2012 <ref name="ref1" /> by researchers from China.
 ==Annotated Information==
 ===Function===
-Please input function information here.
+* '''''BRK1''''' may be required for normal localization of Aurora kinase before the onset of metaphase I, which is responsible for correcting the merotelic attachment.
+* '''''BRK1''''' Is Essential for the Centromeric Localization of SGO1
 ===Expression===
-Please input expression information here.
+* During prophase I, chromosomal behavior in brk1-1 was quite similar to the wild type (Figures 2A and 2E). Whereas at the onset of anaphase I in brk1-1, although homologous chromosomes could separate equally, the two sister chromatids of each chromosome started to disassociate from each other (Figure 2F).
 ===Evolution===
-Please input evolution information here.
+* BRK1 Localizes to Kinetochores during Both Meiosis and Mitosis
 You can also add sub-section(s) at will.
 ==Labs working on this gene==
-Please input related labs here.
+* State Key Laboratory of Plant Genomics and Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
+* College of Plant Protection,Yunnan Agricultural University, Kunming 650201, China
 ==References==
-Please input cited references here.
+<references>
-BRK1, a Bub1-Related Kinase, Is Essential for Generating Proper Tension between Homologous Kinetochores at Metaphase I of Rice Meiosis
+* <ref name="ref1">
 ==Structured Information==

← Older revision	Revision as of 08:43, 12 June 2015
Line 1:	Line 1:
	+	Please input one-sentence summary here.

	+	==Annotated Information==
	+	===Function===
	+	Please input function information here.
	+
	+	===Expression===
	+	Please input expression information here.
	+
	+	===Evolution===
	+	Please input evolution information here.
	+
	+	You can also add sub-section(s) at will.
	+
	+	==Labs working on this gene==
	+	Please input related labs here.
	+
	+	==References==
	+	Please input cited references here.
	+	BRK1, a Bub1-Related Kinase, Is Essential for Generating Proper Tension between Homologous Kinetochores at Metaphase I of Rice Meiosis
	+
	+	==Structured Information==

← Older revision		Revision as of 03:19, 2 June 2014
Line 1:		Line 1:
−	~~Please input one-sentence summary here.~~

−	~~==Annotated Information==~~
−	~~===Function===~~
−	~~Bub1 (for budding uninhibited by benzimidazole 1), one of the main spindle checkpoint kinases, acts as a kinetochore scaffold~~
−	~~for assembling other checkpoint proteins. Here, we identify a plant Bub1-related kinase 1 (BRK1) in rice (Oryza sativa). The~~
−	~~brk1 mutants are sterile due to the precocious separation of sister chromatids at the onset of anaphase I. The centromeric~~
−	~~recruitment of SHUGOSHIN1 and phosphorylation of histone H2A at Thr-134 (H2A-pT134) depend on BRK1. Although the~~
−	~~homologs can faithfully separate from each other at the end of meiosis I, the uncorrected merotelic attachment of paired~~
−	~~sister kinetochores at the early stage of metaphase I in brk1 reduces the tension across homologous kinetochores, causes~~
−	~~the metaphase I spindle to be aberrantly shaped, and subsequently affects the synchronicity of homolog separation at the~~
−	~~onset of anaphase I. In addition, the phosphorylation of inner centromeric histone H3 at Ser-10 (H3-pS10) during diakinesis~~
−	~~depends on BRK1. Therefore, we speculate that BRK1 may be required for normal localization of Aurora kinase before the~~
−	~~onset of metaphase I, which is responsible for correcting the merotelic attachment.~~

@@ Line 12: / Line 12: @@
 onset of anaphase I. In addition, the phosphorylation of inner centromeric histone H3 at Ser-10 (H3-pS10) during diakinesis
 depends on BRK1. Therefore, we speculate that BRK1 may be required for normal localization of Aurora kinase before the
-onset of metaphase I, which is responsible for correcting the merotelic attachment.<ref name="ref1"></ref>
+onset of metaphase I, which is responsible for correcting the merotelic attachment.

← Older revision		Revision as of 03:10, 2 June 2014
Line 2:		Line 2:

	==Annotated Information==		==Annotated Information==
		+	===Function===
		+	Bub1 (for budding uninhibited by benzimidazole 1), one of the main spindle checkpoint kinases, acts as a kinetochore scaffold
		+	for assembling other checkpoint proteins. Here, we identify a plant Bub1-related kinase 1 (BRK1) in rice (Oryza sativa). The
		+	brk1 mutants are sterile due to the precocious separation of sister chromatids at the onset of anaphase I. The centromeric
		+	recruitment of SHUGOSHIN1 and phosphorylation of histone H2A at Thr-134 (H2A-pT134) depend on BRK1. Although the
		+	homologs can faithfully separate from each other at the end of meiosis I, the uncorrected merotelic attachment of paired
		+	sister kinetochores at the early stage of metaphase I in brk1 reduces the tension across homologous kinetochores, causes
		+	the metaphase I spindle to be aberrantly shaped, and subsequently affects the synchronicity of homolog separation at the
		+	onset of anaphase I. In addition, the phosphorylation of inner centromeric histone H3 at Ser-10 (H3-pS10) during diakinesis
		+	depends on BRK1. Therefore, we speculate that BRK1 may be required for normal localization of Aurora kinase before the
		+	onset of metaphase I, which is responsible for correcting the merotelic attachment.

← Older revision		Revision as of 03:07, 2 June 2014
Line 2:		Line 2:

	==Annotated Information==		==Annotated Information==
−	~~===Function===~~
−	~~Bub1 (for budding uninhibited by benzimidazole 1), one of the main spindle checkpoint kinases, acts as a kinetochore scaffold~~
−	~~for assembling other checkpoint proteins. Here, we identify a plant Bub1-related kinase 1 (BRK1) in rice (Oryza sativa). The~~
−	~~brk1 mutants are sterile due to the precocious separation of sister chromatids at the onset of anaphase I. The centromeric~~
−	~~recruitment of SHUGOSHIN1 and phosphorylation of histone H2A at Thr-134 (H2A-pT134) depend on BRK1. Although the~~
−	~~homologs can faithfully separate from each other at the end of meiosis I, the uncorrected merotelic attachment of paired~~
−	~~sister kinetochores at the early stage of metaphase I in brk1 reduces the tension across homologous kinetochores, causes~~
−	~~the metaphase I spindle to be aberrantly shaped, and subsequently affects the synchronicity of homolog separation at the~~
−	~~onset of anaphase I. In addition, the phosphorylation of inner centromeric histone H3 at Ser-10 (H3-pS10) during diakinesis~~
−	~~depends on BRK1. Therefore, we speculate that BRK1 may be required for normal localization of Aurora kinase before the~~
−	~~onset of metaphase I, which is responsible for correcting the merotelic attachment.~~