Os08g0535200 - Revision history

Rice2012: /* Structured Information */

2015-06-12T09:34:15Z

‎Structured Information

Bettychenmei: /* Function */

2014-06-10T14:45:59Z

‎Function

Bettychenmei: /* Function */

2014-06-10T14:41:20Z

‎Function

Bettychenmei: /* Function */

2014-06-10T14:37:48Z

‎Function

Bettychenmei: /* Knowledge Extention */

2014-06-10T14:37:06Z

‎Knowledge Extention

Bettychenmei: /* Function */

2014-06-10T13:47:40Z

‎Function

Bettychenmei: /* Knowledge Extention */

2014-06-10T13:44:23Z

‎Knowledge Extention

Bettychenmei: /* Function */

2014-06-10T13:33:11Z

‎Function

Bettychenmei: /* Expression */

2014-06-10T13:26:49Z

‎Expression

Bettychenmei: /* Expression */

2014-06-10T13:24:49Z

‎Expression

@@ Line 91: / Line 91: @@
 ==Structured Information==
 [[Category:Genes]]
 [[Category:Japonica mRNA]]

@@ Line 18: / Line 18: @@
 interacts and binds specifically to an effector binding element within the Os-11N3 promoter, lending support to the
 predictive models for TAL effector binding specificity. The result indicates that variations in the TAL effector repetitive
-domains are driven by selection to overcome both dominant and recessive forms of resistance to bacterial blight in rice.<ref name="foo">Ginny Antony,Zhou Junhui ,Huang Sheng,et al.Rice xa13 Recessive Resistance to Bacterial Blight Is Defeated
+domains are driven by selection to overcome both dominant and recessive forms of resistance to bacterial blight in rice<ref name="foo">Ginny Antony,Zhou Junhui ,Huang Sheng,et al.Rice xa13 Recessive Resistance to Bacterial Blight Is Defeated
 by Induction of the Disease Susceptibility Gene Os-11N3 The Plant Cell, Vol. 22: 3864–3876</ref>.

@@ Line 11: / Line 11: @@
 Os-8N3 is a susceptibility (S) gene for Xanthomonas oryzae pv oryzae, the causal agent of
-bacterial blight, and the recessive allele is defeated by strains of the pathogen producing any one of the type III effectors
+bacterial blight, and the recessive allele is defeated by strains of the pathogen producing any one of the type III effectors.
 AvrXa7, PthXo2, or PthXo3, which are all members of the transcription activator-like (TAL) effector family. Both AvrXa7 and
 PthXo3 induce the expression of a second member of the N3 gene family, here named Os-11N3.Insertional mutagenesis or
@@ Line 18: / Line 18: @@
 interacts and binds specifically to an effector binding element within the Os-11N3 promoter, lending support to the
 predictive models for TAL effector binding specificity. The result indicates that variations in the TAL effector repetitive
-domains are driven by selection to overcome both dominant and recessive forms of resistance to bacterial blight in rice.
+domains are driven by selection to overcome both dominant and recessive forms of resistance to bacterial blight in rice.<ref name="foo">Ginny Antony,Zhou Junhui ,Huang Sheng,et al.Rice xa13 Recessive Resistance to Bacterial Blight Is Defeated

@@ Line 8: / Line 8: @@
 After fine mapping Of xa13 to a 14.8kb DNA fragment.Sequence analysis of this fragment indicate that this region contained two complete open reading frames and the 5’ end of a predicted hypothetical gene.We found two candidate genes, a prime stretch class is rich in protein gene homologous gene proline, and the other is the nodule gene MtN3 homologous gene<ref>Zhang G, E.R. Angeles, M.L.C,et al.RAPD and RFLP mapping of the bacterial blight resistance gene xa-13 in rice.Theoretical and Applied Genetics, 1996, 93(1-2): 65-70</ref>.Os8N3 is a member of the MtN3 gene family from plants and animals, is elevated upon infection by Xanthomonas oryzae pv. oryzae strain PXO99A and depends on the type III effector gene pthXo1. Os8N3 resides near xa13, and PXO99A failed to induce Os8N3 in rice lines with xa13. Silencing of Os8N3 by inhibitory RNA produced plants that were resistant to infection by strain PXO99A yet remained susceptible to other strains of the pathogen. The effector gene avrXa7 from strain PXO86 enabled PXO99A compatibility on either xa13- or Os8N3-silenced plants. The findings indicate that Os8N3 is a host susceptibility gene for bacterial blight targeted by the type III effector PthXo1. The results support the hypothesis that X. oryzae pv.oryzae commandeers the regulation of otherwise developmentally regulated host genes to induce a state of disease susceptibility<ref>Bing Yang, Akiko Sugio*, and Frank F. White†.Os8N3 is a host disease-susceptibility gene
 for bacterial blight of rice.PNAS July 5, 2006 �vol. 103 �no. 27 �10503–10508</ref>.
 [[File:图片14.8.png|left|thumb|150px|A contig map covering the xa13 region]]Xoo resistance mediated by xa13 is not caused by this amino acid residue variation, but by alteration of promoter regions that leads to differences in the expression of xa13 and Xa13 in reaction to Xoo infection<ref name="foo">Chu ZH, Fu YB,Hong Y, et al.Targeting xa13, a recessive gene for bacterial blight resistance in rice.Theoretical and Applied Genetics, 2006, 112(3): 455-461</ref>.

← Older revision		Revision as of 14:37, 10 June 2014
Line 54:		Line 54:

	TAL effectors are secreted through the TTSS and targeted to host nuclei, a process that is mediated by the conserved N-terminal and C-terminal regions, respectively.TAL effectors combined with a specific gene promoter DNA, similar to eukaryotic transcription factor gene expression in plants start to control the physiological and biochemical processes of plants<ref>T. OGAWA, LIN L , R. E. TABIEN .et al.A new recessive gene for resistance to bacterial blight of rice Rice Genetics Newsletters, 1987, 4(0): 98-100</ref>.		TAL effectors are secreted through the TTSS and targeted to host nuclei, a process that is mediated by the conserved N-terminal and C-terminal regions, respectively.TAL effectors combined with a specific gene promoter DNA, similar to eukaryotic transcription factor gene expression in plants start to control the physiological and biochemical processes of plants<ref>T. OGAWA, LIN L , R. E. TABIEN .et al.A new recessive gene for resistance to bacterial blight of rice Rice Genetics Newsletters, 1987, 4(0): 98-100</ref>.
−
−	~~Os-8N3 is a susceptibility (S) gene for Xanthomonas oryzae pv oryzae, the causal agent of~~
−	~~bacterial blight, and the recessive allele is defeated by strains of the pathogen producing any one of the type III effectors~~
−	~~AvrXa7, PthXo2, or PthXo3, which are all members of the transcription activator-like (TAL) effector family. Both AvrXa7 and~~
−	~~PthXo3 induce the expression of a second member of the N3 gene family, here named Os-11N3.Insertional mutagenesis or~~
−	~~RNA-mediated silencing of Os-11N3 resulted in plants with loss of susceptibility specifically to strains of X. oryzae pv oryzae~~
−	~~dependent on AvrXa7 or PthXo3 for virulence.AvrXa7 drives expression of Os-11N3 and that AvrXa7~~
−	~~interacts and binds specifically to an effector binding element within the Os-11N3 promoter, lending support to the~~
−	~~predictive models for TAL effector binding specificity. The result indicates that variations in the TAL effector repetitive~~
−	~~domains are driven by selection to overcome both dominant and recessive forms of resistance to bacterial blight in rice.~~

	==Labs working on this gene==		==Labs working on this gene==

← Older revision		Revision as of 13:47, 10 June 2014
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		+	[[File:图片OS11.png\|right\|thumb\|150px\|Rice Os-11N3 Represents a Distinct Clade of the N3 Family.]]

	Chen also found XA13 belongs SWEET family can transport from extracellular glucose within the cell , thus providing nutrients for the bacteria , beneficial bacteria growth and reproduction<ref>Chen L Q, Hou B H, Lalonde S, et al. Sugar transporters for intercellular exchange and nutrition of pathogens. Nature, 2010, 468: 527-532.</ref>.		Chen also found XA13 belongs SWEET family can transport from extracellular glucose within the cell , thus providing nutrients for the bacteria , beneficial bacteria growth and reproduction<ref>Chen L Q, Hou B H, Lalonde S, et al. Sugar transporters for intercellular exchange and nutrition of pathogens. Nature, 2010, 468: 527-532.</ref>.

← Older revision		Revision as of 13:44, 10 June 2014
Line 53:		Line 53:

	TAL effectors are secreted through the TTSS and targeted to host nuclei, a process that is mediated by the conserved N-terminal and C-terminal regions, respectively.TAL effectors combined with a specific gene promoter DNA, similar to eukaryotic transcription factor gene expression in plants start to control the physiological and biochemical processes of plants<ref>T. OGAWA, LIN L , R. E. TABIEN .et al.A new recessive gene for resistance to bacterial blight of rice Rice Genetics Newsletters, 1987, 4(0): 98-100</ref>.		TAL effectors are secreted through the TTSS and targeted to host nuclei, a process that is mediated by the conserved N-terminal and C-terminal regions, respectively.TAL effectors combined with a specific gene promoter DNA, similar to eukaryotic transcription factor gene expression in plants start to control the physiological and biochemical processes of plants<ref>T. OGAWA, LIN L , R. E. TABIEN .et al.A new recessive gene for resistance to bacterial blight of rice Rice Genetics Newsletters, 1987, 4(0): 98-100</ref>.
		+
		+	Os-8N3 is a susceptibility (S) gene for Xanthomonas oryzae pv oryzae, the causal agent of
		+	bacterial blight, and the recessive allele is defeated by strains of the pathogen producing any one of the type III effectors
		+	AvrXa7, PthXo2, or PthXo3, which are all members of the transcription activator-like (TAL) effector family. Both AvrXa7 and
		+	PthXo3 induce the expression of a second member of the N3 gene family, here named Os-11N3.Insertional mutagenesis or
		+	RNA-mediated silencing of Os-11N3 resulted in plants with loss of susceptibility specifically to strains of X. oryzae pv oryzae
		+	dependent on AvrXa7 or PthXo3 for virulence.AvrXa7 drives expression of Os-11N3 and that AvrXa7
		+	interacts and binds specifically to an effector binding element within the Os-11N3 promoter, lending support to the
		+	predictive models for TAL effector binding specificity. The result indicates that variations in the TAL effector repetitive
		+	domains are driven by selection to overcome both dominant and recessive forms of resistance to bacterial blight in rice.

	==Labs working on this gene==		==Labs working on this gene==

@@ Line 22: / Line 22: @@
 modulator and as an essential constituent of
 pollen development<ref>Chu, ZH., Yuan M, Yao J,et al.Promoter Mutations of an Essential Gene for Pollen Development Result in Disease Resistance in Rice." Genes Dev 20, no. 10 (2006): 1250-5.</ref>.
 [[File:图片pollen.png|left|thumb|150px|Association of Xa13 expression and pollen development ]]
 [[File:图片deletion.png|right|thumb|150px| Sequence comparison of the promoter regions of xa13 and Xa13 from different rice lines. ]]

@@ Line 42: / Line 42: @@
 ===Expression===
 xa13 expression levels in leaves is very low, but the high level of expression in the ear and anther. RNA interference by inhibiting the expression of xa13, enhanced xa13-mediated resistance, indicating that the absence of a dominant allele xa13 bacterial blight resistance is a must<ref>Antony.G, Zhou J, Huang S, et al. Rice Xa13 Recessive Resistance to Bacterial Blight Is Defeated by Induction of the Disease Susceptibility Gene Os-11n3." Plant Cell 22, no. 11 (2010): 3864-76.</ref>.
 ===Knowledge Extention===