User:Bettychenmei - Revision history

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2014-06-02T10:41:09Z

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Bettychenmei at 10:37, 2 June 2014

2014-06-02T10:37:22Z

Bettychenmei: Created page with "Function The xa13 gene is fully recessive, conferring resistance only in the homozygous status.This gene specifically confers resistance to the Philippine Xoo race 6(PXO99).It..."

2014-06-02T10:36:39Z

Created page with "Function The xa13 gene is fully recessive, conferring resistance only in the homozygous status.This gene specifically confers resistance to the Philippine Xoo race 6(PXO99).It..."

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Function
The xa13 gene is fully recessive, conferring resistance only in the homozygous status.This gene specifically confers resistance to the Philippine Xoo race 6(PXO99).It interacts strongly with other R genes such as xa5, Xa4 and Xa21.
After its fine mapping we found two candidate genes, a prime stretch class is rich in protein gene homologous gene proline, and the other is the nodule gene MtN3 homologous gene.
The dominant allele,Xa13, is required for both bacterial growth and pollen development. Promoter mutations in Xa13 cause down regulation of expression during host–pathogen interaction,resulting in the fully recessive xa13 that confers
race-specific resistance.
Xa13 encodes an indispensable plasma membrane protein of the MtN3/saliva family, which is prevalent in eukaryotes with unknown biochemical function.XA13 protein cooperates with two other proteins, COPT1 and COPT5, to promote removal of copper from xylem vessels, where Xoo multiplies and spreads to cause disease.
Chen also found XA13 belongs SWEET family can transport from extracellular glucose within the cell , thus providing nutrients for the bacteria , beneficial bacteria growth and reproduction .
Localization
Xa13 is Located in the long arm of rice the chromosome 8.
Knowledge relation
The type Ⅲ secretion system (T3SS) effector is considered as one of the key virulence factors
in Xanthomonas oryzae. X. oryzae pv. oryzae and X. oryzae pv. oryzicola cause bacterial leaf blight and bacterial leaf streak in rice, which are important bacterial diseases of rice.
Based on bioinformatic analysis of the bacterial genome and other recent reports, X. oryzae contains at least 28 classes of T3SS effectors, divided into two groups: TAL (transcription activator-like) effectors and non-TAL (non transcription activator-like) effectors.
TAL effectors are secreted through the TTSS and targeted to host nuclei, a process that is mediated by the conserved N-terminal and C-terminal regions, respectively.TAL effectors combined with a specific gene promoter DNA, similar to eukaryotic transcription factor gene expression in plants start to control the physiological and biochemical processes of plants.
Expression
xa13 expression levels in leaves is very low, but the high level of expression in the ear and anther.
RNA interference by inhibiting the expression of xa13, enhanced xa13-mediated resistance, indicating that the absence of a dominant allele xa13 bacterial blight resistance is a must.
Labs working on this gene
National Key Laboratory of Crop Genetic Improvement, National Center of Plant Gene Research (Wuhan), Hua zhong Agricultural University, Wuhan 430070, China
Department of Genetics, Development, and Cell Biology, Iowa State University, Ames, Iowa 50011
National Key Laboratory of Crop Biology ShanDong Provincial Key Laboratory of Agricultural Microbiology Shandong Agricultural University Tai an 271018 Shandong

← Older revision		Revision as of 10:41, 2 June 2014
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−	~~'''Function'''~~	+
−	The xa13 gene is fully recessive, conferring resistance only in the homozygous status.This gene specifically confers resistance to the Philippine Xoo race 6(PXO99).It interacts strongly with other R genes such as xa5, Xa4 and Xa21.
−	~~After its fine mapping we found two candidate genes, a prime stretch class is rich in protein gene homologous gene proline, and the other is the nodule gene MtN3 homologous gene.~~
−	The dominant allele,Xa13, is required for both bacterial growth and pollen development. Promoter mutations in Xa13 cause down regulation of expression during host–pathogen interaction,resulting in the fully recessive xa13 that confers
−	~~race-specific resistance.~~
−	Xa13 encodes an indispensable plasma membrane protein of the MtN3/saliva family, which is prevalent in eukaryotes with unknown biochemical function.XA13 protein cooperates with two other proteins, COPT1 and COPT5, to promote removal of copper from xylem vessels, where Xoo multiplies and spreads to cause disease.
−	~~Chen also found XA13 belongs SWEET family can transport from extracellular glucose within the cell , thus providing nutrients for the bacteria , beneficial bacteria growth and reproduction .~~
−	~~Localization~~
−	~~Xa13 is Located in the long arm of rice the chromosome 8.~~
−	~~Knowledge relation~~
−	~~The type Ⅲ secretion system (T3SS) effector is considered as one of the key virulence factors~~
−	~~in Xanthomonas oryzae. X. oryzae pv. oryzae and X. oryzae pv. oryzicola cause bacterial leaf blight and bacterial leaf streak in rice, which are important bacterial diseases of rice.~~
−	Based on bioinformatic analysis of the bacterial genome and other recent reports, X. oryzae contains at least 28 classes of T3SS effectors, divided into two groups: TAL (transcription activator-like) effectors and non-TAL (non transcription activator-like) effectors.
−	TAL effectors are secreted through the TTSS and targeted to host nuclei, a process that is mediated by the conserved N-terminal and C-terminal regions, respectively.TAL effectors combined with a specific gene promoter DNA, similar to eukaryotic transcription factor gene expression in plants start to control the physiological and biochemical processes of plants.
−	~~Expression~~
−	~~xa13 expression levels in leaves is very low, but the high level of expression in the ear and anther.~~
−	~~RNA interference by inhibiting the expression of xa13, enhanced xa13-mediated resistance, indicating that the absence of a dominant allele xa13 bacterial blight resistance is a must.~~
−	~~Labs working on this gene~~
−	~~National Key Laboratory of Crop Genetic Improvement, National Center of Plant Gene Research (Wuhan), Hua zhong Agricultural University, Wuhan 430070, China~~
−	~~Department of Genetics, Development, and Cell Biology, Iowa State University, Ames, Iowa 50011~~
−	~~National Key Laboratory of Crop Biology ShanDong Provincial Key Laboratory of Agricultural Microbiology Shandong Agricultural University Tai an 271018 Shandong~~

@@ Line 1: / Line 1: @@
-Function
+'''Function'''
 The xa13 gene is fully recessive, conferring resistance only in the homozygous status.This gene specifically confers resistance to the Philippine Xoo race 6(PXO99).It interacts strongly with other R genes such as xa5, Xa4 and Xa21.
 After its fine mapping we found two candidate genes, a prime stretch class is rich in protein gene homologous gene proline, and the other is the nodule gene MtN3 homologous gene.