Difference between revisions of "Os02g0131800"
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==Annotated Information== | ==Annotated Information== | ||
===Function=== | ===Function=== | ||
| − | + | This gene is called Nramp(natural resistance-associated macrophage protein) aluminum transporter 1, which is a member of Nramp family and it is a plasma membrane-localized aluminum transporter recently identified in rice. We all known that the Aluminum (Al) is the most abundant metal in the Earth's crust, but its trivalent ionic form is highly toxic to all organisms at low concentrations. While the rice has the most Al-tolerant cereal crop and the researcher has found that the tolerant of aluminum is concerned with this gene. When expressed in yeast, Nrat1 transports trivalent Al ion, but not other divalent ions, such as manganese, iron, and cadmium, or the Al–citrate complex. Nrat1 is localized at the plasma membranes of all cells of root tips except epidermal cells. Knockout of Nrat1 resulted in decreased Al uptake, increased Al binding to cell wall, and enhanced Al sensitivity, but did not affect the tolerance to other metals. Expression of Nrat1 is up-regulated by Al in the roots and regulated by a C2H2 zinc finger transcription factor (ART1). We therefore concluded that Nrat1 is a plasma membrane-localized transporter for trivalent Al, which is required for a prior step of final Al detoxification through sequestration of Al into vacuoles. | |
===Expression=== | ===Expression=== | ||
Revision as of 08:42, 18 May 2014
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Contents
Annotated Information
Function
This gene is called Nramp(natural resistance-associated macrophage protein) aluminum transporter 1, which is a member of Nramp family and it is a plasma membrane-localized aluminum transporter recently identified in rice. We all known that the Aluminum (Al) is the most abundant metal in the Earth's crust, but its trivalent ionic form is highly toxic to all organisms at low concentrations. While the rice has the most Al-tolerant cereal crop and the researcher has found that the tolerant of aluminum is concerned with this gene. When expressed in yeast, Nrat1 transports trivalent Al ion, but not other divalent ions, such as manganese, iron, and cadmium, or the Al–citrate complex. Nrat1 is localized at the plasma membranes of all cells of root tips except epidermal cells. Knockout of Nrat1 resulted in decreased Al uptake, increased Al binding to cell wall, and enhanced Al sensitivity, but did not affect the tolerance to other metals. Expression of Nrat1 is up-regulated by Al in the roots and regulated by a C2H2 zinc finger transcription factor (ART1). We therefore concluded that Nrat1 is a plasma membrane-localized transporter for trivalent Al, which is required for a prior step of final Al detoxification through sequestration of Al into vacuoles.
Expression
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Evolution
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Labs working on this gene
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References
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Structured Information
| Gene Name |
Os02g0131800 |
|---|---|
| Description |
Similar to Root-specific metal transporter |
| Version |
NM_001052329.1 GI:115444028 GeneID:4328200 |
| Length |
4069 bp |
| Definition |
Oryza sativa Japonica Group Os02g0131800, complete gene. |
| Source |
Oryza sativa Japonica Group ORGANISM Oryza sativa Japonica Group
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP
clade; Ehrhartoideae; Oryzeae; Oryza.
|
| Chromosome | |
| Location |
Chromosome 2:1658576..1662644 |
| Sequence Coding Region |
1658757..1659089,1659223..1659318,1659430..1659561,1659748..1659852,1660020..1660193 |
| Expression | |
| Genome Context |
<gbrowseImage1> name=NC_008395:1658576..1662644 source=RiceChromosome02 preset=GeneLocation </gbrowseImage1> |
| Gene Structure |
<gbrowseImage2> name=NC_008395:1658576..1662644 source=RiceChromosome02 preset=GeneLocation </gbrowseImage2> |
| Coding Sequence |
<cdnaseq>atggaagggactggtgagatgagagaggttggacgagaaactctccatggaggtgtggtgcagagtgttagtgagactgatgagtacaaagaaaagactattgacagtgaaaaagatgggcagtttcgggtgcagccaagatggaggaaattcttggctcatgttgggcctggagctctggtggccattggcttcctagatcctagcaacttggaaactgacatgcaagctggagctgacttcaagtatgagcttctgtgggtcatcttagttgggatggtctttgcacttctgatccaaacattagctgccaaccttggagtgaaaacaggaaggcaccttgctgaactgtgcagggaagagtacccgcactatgtcaacattttcttatggatcattgcggagttggcggtgatttctgatgacattcctgaagtgttgggcacagcttttgcgttcaacatattgcttaagattccagtgtgggctggagttattctcacagtgttcagcaccctcttgcttcttggagtacagagatttggggctcggaagctggagttcatcatagcagcattcatgttcactatggcagcttgcttcttcggagagctaagctatttgaggccgtctgcaggagaggtggtcaagggcatgtttgtcccttctctccaagggaaaggcgctgctgccaatgcgatcgcactctttggcgctatcatcacaccatacaacttgttcttgcactctgctctggtcctgtcaaggaagaccccacgatcagacaaaagcatcagagctgcttgcagatacttccttattgagtgtagtcttgcattcatcgtggctttcctcataaatgtttcagtcgttgttgttgctggatccatttgcaatgcgaataatctttctccagctgatgccaacacgtgtggtgacctaactctgcaatccacacctcttttactcaggaatgttttggggagatcaagctcggtggtgtatgctgttgcgctgctagcttctgggcaaagcaccactatcagttgcacgttcgctgggcaggtcatcatgcaggggtttctggacatgaagatgaagaattgggtaaggaacctcatcacccgagtcatcgccatagctcctagcctcatcgtctccattgtcagtggtccctcaggcgccggcaagctaatcatcctgtcatcaatgatcctgtcatttgagctgccgttcgctctcatccctctactcaagttctgcaacagcagcaagaaagttggacccctcaaggaatccatctatacggtggtgatcgcgtggatcctgagcttcgcgctcatcgtcgtcaacacctacttcctagtgtggacatacgtggactggctcgtccacaacaacctccccaagtatgccaatggcctcatctccgtggtggtgttcgcgctcatggccgcctacctggtcgccgtcgtctacctgacgttcaggaaggacacggtggcgacgtacgtgccggtgccggagcgggcgcaggcgcaggtggaggccggcgggacgccggtggtggacgcctccgccgccgacgaggaccagccggctccgtacaggaaggaccttgccgatgcttccatgtag</cdnaseq> |
| Protein Sequence |
<aaseq>MEGTGEMREVGRETLHGGVVQSVSETDEYKEKTIDSEKDGQFRV QPRWRKFLAHVGPGALVAIGFLDPSNLETDMQAGADFKYELLWVILVGMVFALLIQTL AANLGVKTGRHLAELCREEYPHYVNIFLWIIAELAVISDDIPEVLGTAFAFNILLKIP VWAGVILTVFSTLLLLGVQRFGARKLEFIIAAFMFTMAACFFGELSYLRPSAGEVVKG MFVPSLQGKGAAANAIALFGAIITPYNLFLHSALVLSRKTPRSDKSIRAACRYFLIEC SLAFIVAFLINVSVVVVAGSICNANNLSPADANTCGDLTLQSTPLLLRNVLGRSSSVV YAVALLASGQSTTISCTFAGQVIMQGFLDMKMKNWVRNLITRVIAIAPSLIVSIVSGP SGAGKLIILSSMILSFELPFALIPLLKFCNSSKKVGPLKESIYTVVIAWILSFALIVV NTYFLVWTYVDWLVHNNLPKYANGLISVVVFALMAAYLVAVVYLTFRKDTVATYVPVP ERAQAQVEAGGTPVVDASAADEDQPAPYRKDLADASM</aaseq> |
| Gene Sequence |
<dnaseqindica>3556..3888#3327..3422#3084..3215#2793..2897#2452..2625#2293..2362#2006..2187#1798..1907#1593..1697#1414..1492#477..517#287..362#56..190#gagcaagacatactttttcatatcttccagacaaggtgcattagcaacatagaatatggaagggactggtgagatgagagaggttggacgagaaactctccatggaggtgtggtgcagagtgttagtgagactgatgagtacaaagaaaagactattgacagtgaaaaagatgggcagtttcgggtgcaggtaagcgactacattttgcgcattcatggagttctaatgccacaataagctagtgcttgtttcaatcctatgcttactttttgctgggtggaacagccaagatggaggaaattcttggctcatgttgggcctggagctctggtggccattggcttcctagatcctagcaactgtaagctcctatcttttgcctagagcttcatattgttttgatacgctcattaagaaaaaaagaaaaagaagaggttgaggtggtatagcttttttctgaaacatgatttgacagtggaaactgacatgcaagctggagctgacttcaagtatgaggtacactgcatagttcttgcctcttcgtcttggatctgaactacttttacgaactaattaaccatgtgtcatagatttttgcctgcgcatggaaagggtgaatgtaaccaaggttaatcaaataaagacctggtgaaaggctcccaatcttggaataaatgattgaaagactatcttggaaccatttattagttggaaaattgcctggtttggcctttgaaaattgttaactattacaaagaacctacttagtataagcgtcaggaaaacacttatttgggcatcaaatctgaacaaaacagactcttaaacattttagaggtattcctggatgttttgacttgaaatatctttaaaattccaaatataaataatattttgagattttcttgcactgatttcatagctgaacaagaagaattctaaaccttccactgagggtgtggcctttacagaatattgaaatatgtttccttaaaggcctaaataatcaaagtttaaacttaagtctatcctaaggactgtaccaaaaggactccccgttaactagcataagcaacaatgtcttatttgaagaaagaaaattggattattttggggagtacacatataagaacgttggaatatcaatcattgacttgagatgactctatcatgacatgaaccttatatatatgatataatagtagcagtagtacacgaaatcaaacaaagtctcccatgcctagtaaatggtggtcaataatttgtttctttcctaatatttaaagaagacaaattcaatcaagaaacagaaaagtaggagaaaaacaaaattaactatttcgtttttcctgcctcctctttatataaaatgcttcttctggtaacatcaatttacattttacaatgaacagcttctgtgggtcatcttagttgggatggtctttgcacttctgatccaaacattagctgccaaccttggagtgaaaacaggtatatttcacttaaccattaaccttgctctttgcatgctaatcatgcatcatcaccttatcatcttatgttgtccatgcttttgttgagttctgtacaggaaggcaccttgctgaactgtgcagggaagagtacccgcactatgtcaacattttcttatggatcattgcggagttggcggtgatttctgatgacattcctgaaggttgatcgatgttttatttatttatttatttatttatttatttatttatttatttctgtgctagatttagcatgagtaacacgttcttttgttagtgcagtgttgggcacagcttttgcgttcaacatattgcttaagattccagtgtgggctggagttattctcacagtgttcagcaccctcttgcttcttggagtacagagatttggggtgcgcaaagaatttctcagacttatatgattgtcagatgaattacactgagaatgggctactgacgaattgaccttaccatatgacatgtccaccaggctcggaagctggagttcatcatagcagcattcatgttcactatggcagcttgcttcttcggagagctaagctatttgaggccgtctgcaggagaggtggtcaagggcatgtttgtcccttctctccaagggaaaggcgctgctgccaatgcgatcgcactctttggcgctatcatcacaccgtaagaaacccaatcagttatcagggctttggtgatcgtagctactttttacttgatccatggtacaagttcatgagatgaggagttttcataacatgcatgcagatacaacttgttcttgcactctgctctggtcctgtcaaggaagaccccacgatcagacaaaagcatcagagtaggttgcattgataatagatgatgtaatgatcagctatggtttgttgttgagtggctaatggtttgaccctatcttgtttccgataggctgcttgcagatacttccttattgagtgtagtcttgcattcatcgtggctttcctcataaatgtttcagtcgttgttgttgctggatccatttgcaatgcgaataatctttctccagctgatgccaacacgtgtggtgacctaactctgcaatccacacctcttttactcagggtaagaactgttcgaatgttcatttcctggataaaagatagtactttcagaagcatcttatagacatcttgttctgtaatatggaagaaattacagaccagagctcactgaggatcatgtcagacattctgaattcaagccttattttgattatctcttactttcagaatgttttggggagatcaagctcggtggtgtatgctgttgcgctgctagcttctgggcaaagcaccactatcagttgcacgttcgctgggcaggtcatcatgcaggtaattcagttccgtagtgctcacccttgatagtaaacctggagcagggtttgtcaagtttacactattgatcgaggtgttatcaagtttgtacaaactatttgataccttgcatatcatttgtccactcttgagtattatctatttcagtaaatatagccaacttttgttatgataattatccaggggtttctggacatgaagatgaagaattgggtaaggaacctcatcacccgagtcatcgccatagctcctagcctcatcgtctccattgtcagtggtccctcaggcgccggcaagctaatcatcctgtcatcagtaagactcatcaacctgttttcagctttatttttccaattgaacattctgtaggaattcgctttgctcctccaaaagcaacaatatcctgaattcttgatttggatacagatgatcctgtcatttgagctgccgttcgctctcatccctctactcaagttctgcaacagcagcaagaaagttggacccctcaaggaatccatctatgtaagcttccttaaaccatttctccaaccaaaaaacattcacattcacccacccacacaaacacaaacacgaaaaccgattaattcgccatgctagatacataaattggcaaatgatccaataatttttgcagacggtggtgatcgcgtggatcctgagcttcgcgctcatcgtcgtcaacacctacttcctagtgtggacatacgtggactggctcgtccacaacaacctccccaagtatgccaatggcctcatctccgtggtggtgttcgcgctcatggccgcctacctggtcgccgtcgtctacctgacgttcaggaaggacacggtggcgacgtacgtgccggtgccggagcgggcgcaggcgcaggtggaggccggcgggacgccggtggtggacgcctccgccgccgacgaggaccagccggctccgtacaggaaggaccttgccgatgcttccatgtagccttgataaattattgcttgctgagtagtgcattagttattcctcgtcgtcagtgtataactagatgtgttctctggatgatataatgtgattcgtcattgattttttgttcttcttcttgttgttgtttctaagcagcttagctgtaaattaagtttgagaaaaaaaagtgtgcactact</dnaseqindica> |
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