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| − | Please input one-sentence summary here.
| + | The rice '''''Os08g0313200''''' was reported as '''''OsCBSX1''''' in 2009 <ref name="ref1" /> by researchers from India. |
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| | ==Annotated Information== | | ==Annotated Information== |
| | + | ===Gene Symbol=== |
| | + | *'''''Os08g0313200''''' '''''<=>''''' '''''OsCBSX1''''' |
| | ===Function=== | | ===Function=== |
| − | Please input function information here.
| + | * CBS domains are found to be associated with several proteins of unrelated functions, such as inosine-5'-mono- phosphate dehydrogenase (IMPDH), AMP-activated protein kinase (AMPK), chloride channels (CLC) and cys-tathionine-β-synthase (CBS). |
| − | | + | * Mutation in CBS domains abolish or strongly reduce activation by SAM and cause homocystinuria. |
| − | ===Expression===
| + | * CBS domain of γ-subunit of AMPK acts as sensor of cellular energy status and mutations cause a glycogen storage disease, which is clinically expressed as a familial hypertrophic cardiomyopathy. |
| − | Please input expression information here.
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| | | | |
| | ===Evolution=== | | ===Evolution=== |
| − | Please input evolution information here.
| + | * CBS domain exists not only in archaebacterial proteins, but also in eubacterial and eukaryotic proteins |
| | + | * In CBS protein, C-terminal CBS domain exerts an autoin-hibitory effect on the CBS activity, while binding of SAM (S-adenosylmethionine) with CBS domain induces a conformational change which relieves the autoinhibitory effect. |
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| | You can also add sub-section(s) at will. | | You can also add sub-section(s) at will. |
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| | ==Labs working on this gene== | | ==Labs working on this gene== |
| − | Please input related labs here.
| + | * Centre for Computational Biology and Bioinformatics, School of Information Technology, Jawaharlal Nehru University, New Delhi 110067, India |
| | + | * Plant Molecular Biology, International Centre for Genetic Engineering and Biotechnology, New Delhi 110067, India |
| | + | * Stress Physiology and Molecular Biology, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India |
| | | | |
| | ==References== | | ==References== |
| − | Please input cited references here.
| + | <references> |
| | + | * <ref name="ref1"> |
| | + | Kushwaha HR, Singh AK, Sopory SK, Singla-Pareek SL, Pareek A. Genome wide |
| | + | expression analysis of CBS domain containing proteins in Arabidopsis thaliana |
| | + | (L.) Heynh and Oryza sativa L. reveals their developmental and stress regulation. |
| | + | BMC Genomics. 2009 Apr 28;10:200. doi: 10.1186/1471-2164-10-200. PubMed PMID: |
| | + | 19400948; PubMed Central PMCID: PMC2694836. |
| | + | |
| | + | </ref> |
| | + | </references> |
| | | | |
| | ==Structured Information== | | ==Structured Information== |
| − | {{JaponicaGene|
| + | [[Category:Genes]][[Category:Oryza Sativa Japonica Group]][[Category:Japonica Chromosome 8]] |
| − | GeneName = Os08g0313200|
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| − | Description = Similar to (clone pCDH1) carbon monoxide dehydrogenase (cdhA)|
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| − | Version = NM_001068049.1 GI:115475835 GeneID:4345241|
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| − | Length = 8491 bp|
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| − | Definition = Oryza sativa Japonica Group Os08g0313200, complete gene.|
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| − | Source = Oryza sativa Japonica Group
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| − | | |
| − | ORGANISM Oryza sativa Japonica Group
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| − | Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
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| − | Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP
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| − | clade; Ehrhartoideae; Oryzeae; Oryza.
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| − | |
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| − | Chromosome = [[:category:Japonica Chromosome 8|Chromosome 8]]|
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| − | AP = Chromosome 8:13447088..13455578|
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| − | CDS = 13447126..13447329,13452347..13452434,13452510..13452574,13453358..13453406,13453945..13453997<br>,13454715..13454830,13454947..13455004,13455085..13455159|
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| − | GCID = <gbrowseImage1>
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| − | name=NC_008401:13447088..13455578
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| − | source=RiceChromosome08
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| − | preset=GeneLocation
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| − | </gbrowseImage1>|
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| − | GSID = <gbrowseImage2>
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| − | name=NC_008401:13447088..13455578
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| − | source=RiceChromosome08
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| − | preset=GeneLocation
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| − | </gbrowseImage2>|
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| − | CDNA = <cdnaseq>atgggcgccacgctgctgctcctgtgcgccgacttctcggctgttgccggcggccgccggcggccttccctgccctcggagccacggttggcggctcccgctgctgggtcccgtgcgccgccgtcgagagcctccgtccgcccgtccgctgccgccgccccgctcgccgcgcgcggcctgccgcaccacgcctccgtcgctgggcaaaacagtggaatttacactgttggtgattttatgactaaaagggaagaactccatgttgtgaagtcaacaacttcagtcgatgaagcccttgagatgctggtggagcataggataactggctttcctgttattgatgacgagtggaatttggttggcgttgtgtcagattatgatctcttagcactcgattcaatatcaggaaatggacttgcggaagtagacatatttcctgaggtggatagtacttggaagacgttcaatgagatacagaagctcttgagcaaaaccaatgggaaagtcattggtgatgttatgacgtctgcacctcttgtggtgcgtgaaactactaaccttgaagatgctgcaaggttactccttgaaactaagtaccgcaggttacctgtagttgacagttcaggcaaattggttgggatcataacaagagggaacgtcgtcagggctgcccttaaaattaagaaaaagtttgaaggtgaactttga</cdnaseq>|
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| − | AA = <aaseq>MGATLLLLCADFSAVAGGRRRPSLPSEPRLAAPAAGSRAPPSRA SVRPSAAAAPLAARGLPHHASVAGQNSGIYTVGDFMTKREELHVVKSTTSVDEALEML VEHRITGFPVIDDEWNLVGVVSDYDLLALDSISGNGLAEVDIFPEVDSTWKTFNEIQK LLSKTNGKVIGDVMTSAPLVVRETTNLEDAARLLLETKYRRLPVVDSSGKLVGIITRG NVVRAALKIKKKFEGEL</aaseq>|
| |
| − | DNA = <dnaseqindica>39..242#5260..5347#5423..5487#6271..6319#6858..6910#7628..7743#7860..7917#7998..8072#gtgtgtgtgtgtgacgggggtcgggggaacctgctcccatgggcgccacgctgctgctcctgtgcgccgacttctcggctgttgccggcggccgccggcggccttccctgccctcggagccacggttggcggctcccgctgctgggtcccgtgcgccgccgtcgagagcctccgtccgcccgtccgctgccgccgccccgctcgccgcgcgcggcctgccgcaccacgcctccgtcgctggggtgagttctctgtccccattgccttgtttaatgtttattcgtgctgtcttcttgacttagtattcgcagttgaattgtggcgtggacgcatggagttttgtttaggcaggaactttgattgaccgtgcagactgctgagggtggatgtgatcatcttggtgatcgtgtgatttcgtcgatatttttaggatttaccattctccagaatctaattgataaaattccacccgtcagttgatagtgttctagaattggccatctggtcctccggatctggcaccatcgctcattcgttcctccaccaggactcttaagctctcatgctcctctatctatctaatcttctattcttctggcattgaccaagccatgatctggtgcgcgactgcctagactggaactagataagaaattgttgagcgggaacttgagaaattgaagataccttatgaacaaactggatatgttgcaacgaaaagggctagcaactagcaagaatcatgttctctgttcgtgttgtaggatgtcgtcgaagaagacgaggacgaagcgacggagtaacggcttgaggaagaacgcgccagagcacgcggttgtcttgccaccagaaccccatggagagtacctcaaagtgtaatggggccgaggcggcacagccactagacaccaaggacgacgtcgaacccttgtaaggtagggagtagatgtcgatgtcgaaaaacttgtcgtggatgtggacatagagatcgtgtttgcagcccgagcaagaaacatggtcactgttctaacgttgatgtcttggagtggtgtcagctcaagtcccaggcgtcttggagtggtgtcagcttgagtcccaggcggcgagcagcttcgcccgcgatgaaattatgcgtggagcctgagtccacaagggcgacgagtaggggtggcaatttcccccacaggggcgggggaaatttctcacccgtgggtgagcgggcgcggggccctattagtttctggggccggggcagcatcttcacccgcgggaccctggagttttgagcaagagatagcccactagctaagaaaagcccaccaaacaacaaaagcagcccacgtactgccatcacaagtctggatggcaagcccattaagaaataaccttatgcagcccactttagaggagatataagttcaacatcaaaacctaatccatctagcatcaggcatcagttcctggcggcggcaatcgagcgaggctaggaggatgaggcacgcacacgcatcgtctcgtgtcgcgcttcggcttctacccacccgccgttattgccaagccgtcgacgaagcttcaccgaccgcgttatcactcccggctcccatgtctcgttggctgtcgactcctcgcgtctttcccctccatctctaggcgcctccttatcctatctcttctttgagtcgtttcccttcgtcttcaagtccctagcaccattctcttctccctccagcctccaggcgccagcagttgccacttgcatcggggctacgggtacccggccggagttcggggcccaacaggggccggggccggggatcaattttgccccgatcgtcactccaaggctggggccgggtgaacccgtaagtgagcgggggcagggccgttcctgtccaacccgccctgttgccacccctagcgacgaggtggtgtcccttgatgatgatcggcaattgcatcgtgcggctggtgcaaatgctcgagagagcgaggaggaacacctctatcgcctcggtatcttcaggggtaaggacggtggcgttgtcgttaatggacttgacctagaaaatcccctttgcagcacccttgtgactgggtttaaacttctccggatagttgaagcagaagcccttggagcgccgttcattcatctcctctggcgtgaggcacttgaagcgaggcttggcatcggctaccggcggaagggccaacagttacttgtgcgtggaggaagacgacccggtcttgacaggggctggtgttcgtgtagacgtgatcaggtgtggggcaaagcaggtcttgtgctgaggtttgggcgccatgagcgaaacgctcttgtcttggtcctcctgccgctgctcgtaagcccatgccaggctcatggccatctgtagcgagcagggtttctgcatctcaatgttcgtgcgagtggcttaagcaggttggcgatgaaaagcttaactacctgggatgccatcaagggcccggttcacgctaggtgcgagaggagccgacgctagtattcttcgactgtcccagtacagcggaggtgggatagcattcgcgtagtattcttggaacgcaccggtggtccaaaacgaaggttgacgaagttggcgaagcgcgaccacgttaggacgccctcagtgcattgagttggtgataccattcacgtgctgcaccggtcatgtgatatgaggccagccacacctcttcggctcttcttcctccaacatctcctgtccctgaaaaaactgctcagtgattgagccagtttaacgggtcatcttcatcgtcgtgcgtcaaaaaattgagtttgtggtagcatgatgcaccgcggtgaccgcggcgatcgtcgtgatctgccggagatcggtcacgatgctaaggtgggggcgaacgatctccttcctgatatttctccatgcgagcgatgtgttggtcatgccgatcaagcctggtggtgagggaggtgatgtgtccgatcagctggtcgagcttggcttcaacaccgcgtgacgcggcgtttggctcgacgtgctcgccaaacatagcgagagcggcgaatggctatgatgccaagctgataggcgcacggcggcggtggtgttgtagcggcgaatgctcgaaagggatgattgcggagggggtaacagtgatactcacgatcgccctcaggccgaaaatagggctcatccccagccagcgagaggctctgaatgtgtagagaactagattggattgatcttgcttgtttgattacaatgcagtgcccccttttataatcaagggaataactaatcttagagataaaggacaaagcttgagaacctaacaaccgatcctaacaaactgataatgaaaacaaaaaacaatgagtatggtgctagttggcgatgtacggaatatccgcagaatttggcgcagcgtttgcggcgctgttgtgtttcttttgtcaacaacggcgctgataggtacggctgaagaaatgatccatatcgaatacattgatgaggtgcttctgtttttgcatgcatggttttgacctgtcagtaaatgaattgagttccttctgcttgttcccaaggtaagcttgaaatttgaaaagacaatatgacacccaccaggtttatggttttgtgggcgttgttaaaaggtttcgttgtcctacatctcttccatctatttctctacattgttagcaccaacctcctccacattaactcagattcaatgttactctctcactggactattcaatgtcgcccttatgtcagctttgatgccaccgggcaagatatgcaacatgttcactttggacttggtgctttcagattcacctggctccacttggcctggcacctccttatgggttatgatatctagatgtgtggggaatggtcactggttatgtcgcctgcaggtgacctcaccagtggtgcgcacaacaacaatgctcccccgtcttaataagctatgttgtcaagctatggatgcaccactgcagcaaccatgaagtgctccatggatagccaggataagtttgtgtttcagtccaagtcgcttcagcatggagatgcaagcaagccacatgagatcaacctgtttgtgcttaccatcaaaatccacagccaaaccaccattgccttcctcaaattgttgcaacatgctccctccgtctcataaaataccaacctagtactgaatgtgacgcatcttagtacaacgaatctgaatataagatgtgtcacatccagtactaggttggtattttatgagagggagggagtaagtgcatagccaataaccagcaagtgttgttgcagtttccatgggcatagtaaagactactcatttgccttccgttctggttaattcagtgtggattaaaccaatcaatacatttcagtactgaaaagtgaatactcacacgtaagatctgacatgacaggatttgcagtggatctctagtaagcttcatccaggagtggatatttattgagctccatcaagctgtggctccttctgttgtttttctctgttgctgagtggggggatgggagggaaagaacagacgatgaggaagaactaatattgagattcagtaagtaattcagtgagtgctttcttcttttataagaagagtgtcagcttggaagaagaaaatgaaatacgaacaaccgcgctggtcgtaatagatcgacttgaatgcgtcttcttgctccagcattcaagttccatttcaagggaggacgatgtaccatgatactttcagttttgtcgagccctgctttggtctctggtttgatggttgtacgtgctaaaaatccggtacattccgttttgtttcccatcctagtcttttgcgacacagctggtttacttattttgttaggtctcgacttatccgctatgatctccccagtagttcatataggagctattgccgtttcattccgagtggcatgcatatcctagtgatgatgaggcttgatttgacaattcagttttgagtcggcccaaaactgggttgagtgagttgaaaggggtcagatgaaaaatttagtaggttgatgttgtattctaattgaaggttatgttttggacagaggtagttcaagattgatgtggacttgttcctctataacttccttctctatgaggcttgacctccaattttatgtggtacatacaaatttctatttgcaggattgagatatatttatccatattaatattcctgaatttcttgttattcagcaaaacagtggaatttacactgttggtgattttatgactaaaagggaagaactccatgttgtgaagtcaacaacttcagtcgatgaaggttcctttccccctttatgctgtgtgctcttctttctttcattaggaggtaccaacttatcttatatttgagcagcccttgagatgctggtggagcataggataactggctttcctgttattgatgacgagtggaatttggtaagtggtataatattgtatttaaatattgtctttttgaagcacaccactatttacggtgaaccttcatattgagttagctacttgtagaggagggccagatgtcattgcttcaggggattagggtattatattggagagatagcataacttgatatgactgaactcagcaaatagatggaatatatatatttcttgcttgattgataaaagaatattgtccattctttagtgattactcaacttgatattcatatttatatttcacttttcttattaatcacaaattctacgttctaattctcctagatttatgaacacatgttggcgactgctgtttttggaccccttaagccaaggctggccatctgtcacattttgcttctgtacatcagcctacattacttgtctgtccatgtccacacatgattgaacttgggactttttcttggttcgctctttttctgtttctgagtttcacgttcttgccagtcaccactatttttctgtaacatataacatatcaaagtttttgttgataatatgttagttatgttcaacctttaccttttagagcattcgaaagttcaatgtttttcttttacttagcagtattcatacagaaaatgtagacctttagctgcttaatttcctgttatgttgaataaaccttaaactctgaaccaagcatgctttgtcccagttataacatagtgttgctgtgcaatatagtttgtgtaagtgttgcattaatgtgtgccagtatttatttcccatccgcaggttggcgttgtgtcagattatgatctcttagcactcgattcaatatcaggtattcttgtaatagttgatgctggcattcactattacatagttgaaatcgtagttattgggaccagctgatgaactggtgaactgctggttcaaattatattatcttttaaccattttcatgttaaaataatggtttataaggctaaatataaaattataatggctacatagacatcaattcttattccaatcaataaccaggcgttgatccagtggtattgaacgtgtggagattccctagaagccagagcttgtaccatggtcttttagcaaaccaagctggtctaagctctggttctgatttttcccagttggactgccagttccacctggtttaaataactgtgtttcaaatctcatgtagttgcaagttgcaacatcatatggtttggcttcatctagtttacagcatgtttattgaataatcttggaacctgggatcattttggtattgtttatctgtcaaattagcaacagctttcccatgttatgatgctcactgtgtattgttctactgttttaataatcttcttcaggaaatggacttgcggaagtagacatatttcctgaggtggatagtacttggaaggtacttacaaacaaatctatttttaactttgatttcagtttttgtccagctcaagtggaccttttttataaaaaattatagaagttttttaaaagaaattcttgataaaagtaatttttctaggccattgccatgttaagatgatcccctcgaagtcaatctgatactgcaattttactattttagtgaatcacataaccatttggtggctggtctttaccattccatctgtccaagatttggattgttcaactggacaattgtgatgcttggctgaaacataatgtacacactttatgttgatttggaccaagtttcatttatttcttgcatgtacacagtttgcatatccttcagaaaagagtggataggatagtttcacactcagcctgttgtatttttcacagtgaactctcttaaaccatcagacttgagattcttatcttgttcggggtgctagatgtcacttgtttgtgcaacaatatctctttggatgagaagtacacagtagtgtcctggaaccttcattgcagttgatggaatatcactattaacaactaaattagttagaatattgcatcgatgcagataagaatgtggcattttcttcaaacttgcctatcgactatcgtgtatgctttgttccttttatttatatatgtttttttcctactcgtgttcaactgtttctgattttgatgaattgatactctatagacgttcaatgagatacagaagctcttgagcaaaaccaatgggaaagtcattggtgatgttatgacgtctgcacctcttgtggtgcgtgaaactactaaccttgaagatgctgcaaggtattttcagaaaactgcaaacaattctgatatacatcactaacttacttttaaatttctcaaaaaaagggatatcctttattattcaataaaaattatgatgtcatattccacaggttactccttgaaactaagtaccgcaggttacctgtagttgacagttcaggcaaattggtgagtgggcaaaccttatctctttccttttattcttttgcctgagttcagttgttttgagacaaacttatatttggaaggttgggatcataacaagagggaacgtcgtcagggctgcccttaaaattaagaaaaagtttgaaggtgaactttgaatggatactgtggattgaccctttggagacatttaggggcttctacatcggggagatgaacatacggctaggcaattgaattcaagccattgtttcagtggcaagcgaacttcgccaccatgtttataccaggcgtaagttcaataactgccaagtgtaaagtgatggttaaaggactcgtagcagttgaaagggaagctctaattttctactatactagtgccatgctatatcagctcatgggttgtaacggtatctagagacagatgaatggttttatggtatttagttttttttagagtaaatttcataaaactatgggtattttgtataatttatcacaaacatacgggccaatttgatttaaaggaatgccaaaggacttttggaggaataggattccaaaggattttttccct</dnaseqindica>|
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| − | Link = [http://www.ncbi.nlm.nih.gov/nuccore/NM_001068049.1 RefSeq:Os08g0313200]|
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| − | }}
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| − | [[Category:Genes]] | |
| − | [[Category:Japonica mRNA]]
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| − | [[Category:Oryza Sativa Japonica Group]] | |
| − | [[Category:Japonica Genes]] | |
| − | [[Category:Japonica Chromosome 8]]
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| − | [[Category:Chromosome 8]]
| |
