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| − | {{JaponicaGene|
| + | The rice '''''Os04g0401300''''' was reported as '''''OsCBSCBS4a''''' in 2009 <ref name="ref1" /> by researchers from India. |
| − | GeneName = Os04g0401300|
| + | ==Annotated Information== |
| − | Description = CBS domain containing protein|
| + | ===Gene Symbol=== |
| − | Version = NM_001059222.2 GI:297602644 GeneID:4335727|
| + | *'''''Os04g0401300''''' '''''<=>''''' '''''OsCBSCBS4a''''' |
| − | Length = 7651 bp|
| + | ===Function=== |
| − | Definition = Oryza sativa Japonica Group Os04g0401300, complete gene.|
| + | * CBS domains are found to be associated with several proteins of unrelated functions, such as inosine-5'-mono- phosphate dehydrogenase (IMPDH), AMP-activated protein kinase (AMPK), chloride channels (CLC) and cys-tathionine-β-synthase (CBS). |
| − | Source = Oryza sativa Japonica Group
| + | * Mutation in CBS domains abolish or strongly reduce activation by SAM and cause homocystinuria. |
| − | | + | * CBS domain of γ-subunit of AMPK acts as sensor of cellular energy status and mutations cause a glycogen storage disease, which is clinically expressed as a familial hypertrophic cardiomyopathy. |
| − | ORGANISM Oryza sativa Japonica Group
| + | ===Evolution=== |
| − | Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
| + | * CBS domain exists not only in archaebacterial proteins, but also in eubacterial and eukaryotic proteins |
| − | Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP
| + | * In CBS protein, C-terminal CBS domain exerts an autoin-hibitory effect on the CBS activity, while binding of SAM (S-adenosylmethionine) with CBS domain induces a conformational change which relieves the autoinhibitory effect. |
| − | clade; Ehrhartoideae; Oryzeae; Oryza.
| + | You can also add sub-section(s) at will. |
| − | |
| + | ==Labs working on this gene== |
| − | Chromosome = [[:category:Japonica Chromosome 4|Chromosome 4]]|
| + | * Centre for Computational Biology and Bioinformatics, School of Information Technology, Jawaharlal Nehru University, New Delhi 110067, India |
| − | AP = Chromosome 4:19872374..19880024|
| + | * Plant Molecular Biology, International Centre for Genetic Engineering and Biotechnology, New Delhi 110067, India |
| − | CDS = 19872456..19872547,19872663..19872762,19873516..19873585,19873759..19873822,19874946..19875119<br>,19875220..19875361,19875828..19875959,19876031..19876120,19876508..19876567<br>,19876642..19876830|
| + | * Stress Physiology and Molecular Biology, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India |
| − | GCID = <gbrowseImage1>
| + | ==References== |
| − | name=NC_008397:19872374..19880024
| + | <references> |
| − | source=RiceChromosome04
| + | * <ref name="ref1"> |
| − | preset=GeneLocation
| + | Kushwaha HR, Singh AK, Sopory SK, Singla-Pareek SL, Pareek A. Genome wide |
| − | </gbrowseImage1>| | + | expression analysis of CBS domain containing proteins in Arabidopsis thaliana |
| − | GSID = <gbrowseImage2>
| + | (L.) Heynh and Oryza sativa L. reveals their developmental and stress regulation. |
| − | name=NC_008397:19872374..19880024 | + | BMC Genomics. 2009 Apr 28;10:200. doi: 10.1186/1471-2164-10-200. PubMed PMID: |
| − | source=RiceChromosome04
| + | 19400948; PubMed Central PMCID: PMC2694836. |
| − | preset=GeneLocation
| + | </ref> |
| − | </gbrowseImage2>|
| + | </references> |
| − | CDNA = <cdnaseq>ttttgtgtattttatttatgctacctaataacttatagtctgttatgcattatttccaattatctcaagcagatgcccccagatcagttatctcaaaactcaggcgtgcagatagcaattttccgccatcgagtctctgagatattattacataataccatatatgatgttgttcctgtttctagcaagatagcagttttggatgctcgtcttcctgtcaagcaagcctttaaaatcatgcatgatgagggtctttctttggttcctctttgggatgatcagcagcaaaccgtaacaggcatgctaaccgcatccgattttgtattaattttgagaaagctgcagagaaacattcgaactcttggccatgaggaacttgaaatgcattcagtgtctgcttggaaagaagcaaaattgcagttttatgggggacctgatgttgctgccattcagagaaggccattaattcatgttaaggattcagataatttaagggatgtggcattggctataattagaaatgaaatatcttcagttcctatctttaagccctcaacggattcatcagggatgcctttgcttggtcttgcaacccttccagggattgtgaaatttatttgctcaaagctgcaagaacagcctgaagggtactcatttctgcaaaaccagattgtcagtatgcctattggtacatggtcaccacatactggcaaggcaagcaatagacagcttagaacttcgcgaccaagcactcctctaaattcatgcctggatttgctgcttgaagatagagtaagctcaattcctatagttgacgataatggcgctctccttgatgtctactcgctcagtgatatcatggctctaggcaagaatgatgtctacactcgtattgagcttgaacaggtgacggtggagcatgccttggagctgcaataccaggtgaatggccgaagacactgtcatacctgcttgagcactagtaccttcctggaggttttggagcaattgtcagctccaggggtgcggcgagtcgtcgttattgaaccaaggagcagatttgtgcaaggaataatctcattgagggacgcatttacatttctcattggataa</cdnaseq>|
| + | ==Structured Information== |
| − | AA = <aaseq>FCVFYLCYLITYSLLCIISNYLKQMPPDQLSQNSGVQIAIFRHR VSEILLHNTIYDVVPVSSKIAVLDARLPVKQAFKIMHDEGLSLVPLWDDQQQTVTGML TASDFVLILRKLQRNIRTLGHEELEMHSVSAWKEAKLQFYGGPDVAAIQRRPLIHVKD SDNLRDVALAIIRNEISSVPIFKPSTDSSGMPLLGLATLPGIVKFICSKLQEQPEGYS FLQNQIVSMPIGTWSPHTGKASNRQLRTSRPSTPLNSCLDLLLEDRVSSIPIVDDNGA LLDVYSLSDIMALGKNDVYTRIELEQVTVEHALELQYQVNGRRHCHTCLSTSTFLEVL EQLSAPGVRRVVVIEPRSRFVQGIISLRDAFTFLIG</aaseq>|
| + | [[Category:Genes]][[Category:Oryza Sativa Japonica Group]][[Category:Japonica Chromosome 4]] |
| − | DNA = <dnaseqindica>7478..7569#7263..7362#6440..6509#6203..6266#4906..5079#4664..4805#4066..4197#3905..3994#3458..3517#3195..3383#aggctccaacaccaacccaaagctctctcgaaagcgaacaaaacaaacgcccacacacacacggtgacacgcaccccgacgccccccctcccctttgcttctccgcctccgcctccgcctccctcctcacgcacgccaaaaaatttccctcttttcctcattctccgcctccttataatctcaattcaccaccaccgtccttctcgctctcgctctcgctgctgctcctgcaggtcccccaatcccgtgggcgtggggggggggggggggtgttcggggttcttgctttgctgggatggtcgacgcctaggtgttttgctttgctttgcttttgctagggttcttgaggggggggggggggtggttgcccgggggcttctccaaacatggtgctgcggcgcttcgcgtggccgtacggcggccagcgggcctccttctgcggcagcttcaccgggtgggtttgggattgaggggaaaaaggatcgatcttgggcagggggggttgagggaaaggcgggatctttcctttttctattttttcgggttgatgttttgctgcgggaaatgctgaatttctttgttttctgcgcttgtgctgcgtggttttttttgtgtttgggcgcaggtggagggagtgccccatggggctcgtcggggccgagttccaggtggtgttcgatctgccccccggggtttatcaggtgcgcgcccttccagccgaattccccggattcgggctactccttcgtttcgattatgcgtttttgtttatgccatgttttctttacaccggttgtggtatgggtgtgctaggcttgctagctcttgattgtgtgtttgtgcctgatgagtgtgtagattgcttggggttgggatcgaattacgctaattcgcgatagattagtgcgccgattctgttttgatatctttgatgtgtgactgttttgtcggaagcgcgtttgggcggcaatgcatccaaatgttagttggtagttgccgtcgatggccgccgaggtgtgctcacgcaatgcattggagcttataatgcgtggcggggactggtgtcccttccacagataggaggtagtgtggttgggttcttggagtgacctattttatgcatagcagctgtactaatcgaccttgggtaatacgcttaatggttaaaccctgaattgtgcgcggtatcaagtgccgttgagtgttgatgactagggtttatgtggaccttatccccttactgactatttccattaaatgtattacctcatgaccgccgtatgaaatcctctcgttagattcagtgatgtacatatgtgttgacatgattgatgtcttattcggtaaaatatgtactcattttttcatcattctatgccctgtgcaccaacagattgaatagtgctttagaaaaccatgtactcctacgaggtagtacaaggaagtcaaataaatggatgtatgccacatttttactttggtacttccatgactagctatggtctttttttcttttgactgaaattgaactcattacagagctctatgcaagcaaaggacattatctgggactttgaggggaaggaagccctcccccctatgaatattgaaatgttgaccacctgaaaaagagaaaaatagaggcttggtttgactgcttgtcttggctgtaccgttaattagctttcacacatgtagctttgcagtttgacttatatgataaccgttaaattagctttcacacatgtggctttacagtttgacttaaatgataaccgcaagaattcaaatagcatagcttttgcatgatagagtttgtcctatttgataagcagaactctatgttttcaatttagtccataggaaaactagtcgttaagtcttacagcattcttttcaatttagtccgtaggaaaactagtcgttaagtcttacaacattcttgtacagtaggaacatgcctagtatgtggggaccaggttgccctcccctgtttccatagttccagacaataacttgtaggcgttacatgatggctgctgcacatttgattgtccatacagttgcggcatcaaaattgtcctctaatgccatcataatgagtcgtgaaggcacatgaatacaaatagatctgttttaggttcccacatctccagttattcgtatttcaaaagattgatttattatatttttttcctcaaaacatatgatttgctgcatttatgccagtttccccatattgtttatcttccttttatctactttcttaattaggactccttcattttgttatattttttcgatatcttccgaattcttatctactacatctgtcccatgatataaggggtactaggtttccttgaagtggttaagggggaaggaaaaagactttgatgctctttattaaatgaggggtttgtgggaagtgagaaggtggttggcataaaatgtgaagaaaattgaatgaaggatgattgatgggacaaggagcacttgaaagcccttgtatttagggacaaaatttgaatccttgtatcacttatattatggaaccgagggagtagcaatcaatacagtgttcttttcgtctaaaaaaaaatcaatagcgatagatatcagaaattttcataatcatgttggattttgtattttggatgtttgtagacgtcatttaattctggaaatgtagccaagcatgacgtgcctgatatattactgctagagtataatgcactttccaagtatttggtgttacaccatgcacttctatagagaatccactcactctttattggacactctattgcttatggccactgtgtgattgcttgtttctgttgttatgttagctttagcaaacaacttgtacacttctagtatcaaattatgtgaagatagtcgatttctataccagtgccctgctatttgtatacaactttcttgtgcttagtgttttgctttcaatacattgatgtgttcttttggtgtcacatagtaccggtttttggttgatggtgtctggcgatgtgatgagacgaaaccttgtgtacgggatgaatatgggttgattagcaatgaagttcttgtggataatacacatccggttgtacagccagaaacttccatcagagtagtgagtatggatgagggtactatactgacaacagtatgtatcaaagtttcatttgtaattttgtgtattttatttatgctacctaataacttatagtctgttatgcattatttccaattatctcaagcagatgcccccagatcagttatctcaaaactcaggcgtgcagatagcaattttccgccatcgagtctctgagatattattacataataccatatatgatgttgttcctgtttctagcaaggttagattattcttttgtagttagcactttcgtttaggccatatcaattataacatttggtatatgcatttcagatagcagttttggatgctcgtcttcctgtcaagcaagcctttaaaatcatgcatgatgaggtatgtctttgcaggactatgcatttattttctttcttctttttttacttcctgctgtttgcatattcattaaaatttcctatgtttgtttatcatgttattgaataattgcaatatttgtttatttatatgttaggagcgatcgatttgtttcttcattttacaatcaaacaagaatttctagcagaacaaatttattttttgttgactaataactaacaccattgtttccatcaaagaaaaacactgctaaataagcaaaattttctggtaaattatcatttgtccttgcatattcatgtatgtaggtagtccaaaaattttgattgctccttgtgtgatcaaatactgtaagaattcatcgtaatttcacttctcttgttttagggtctttctttggttcctctttgggatgatcagcagcaaaccgtaacaggcatgctaaccgcatccgattttgtattaattttgagaaaggtgagactaaattgttgtgtttctccttcgataagcacttttacattgtttatcaattcttgggtctgcagctgcagagaaacattcgaactcttggccatgaggaacttgaaatgcattcagtgtctgcttggaaagaagcaaaattgcagttttatgggggacctgatgttgctgccattcagagaaggccattaattcatgtatatctgcatctatttcccagatatcgttcatttgatttgctgtctaaatattactcatggatattacagaaaaaacggtggatattataaaatcaggtttacaatgaccttaataaatatttccttcatcatttcctcaaattgtatgtcatagtgatagtgatatgctgttgtgcatcaaggctgacatacggataactcctgtgttttacgtatgatatgtgattgtacatttcattgttgagattcattcagctaaaataaaggccactttggatatgaggggttgagcctttggttattcaagatcaaatccctatgtctaataagaccatagcagtgtgttttaatcttctgtattgatataagttcaacattgatgggattacctattcatttcatttatttgaacatttctattttctagtaattgatccattattttcctcttatgtttcttcaggttaaggattcagataatttaagggatgtggcattggctataattagaaatgaaatatcttcagttcctatctttaagccctcaacggattcatcagggatgcctttgcttggtcttgcaacccttccagggattgtgaaatgtacggaatcatttttaataatactacaactgttcattctgacagctaaattgatccgagcctcaaattaagctcacttttatcttgatgctgtatttagttatttgctcaaagctgcaagaacagcctgaagggtactcatttctgcaaaaccagattgtcagtatgcctattggtacatggtcaccacatactggcaaggcaagcaatagacagcttagaacttcgcgaccaagcactcctctaaattcatgcctggatttgctgcttgaaggtaacatgtaattgatatttaaaatgcattgttttttcttgaataatatttaaaatgcatagaattatactattctccctaccgatttttaagaacatatcagtgacattgtaattgttggccacaatcaatcagttagttctttctaggattacattttttaattccacattaaagacatgaaataaattatcttacttgacatgcaaatgctaggtaaggttatcagttatggactgccctatggcagtaccattagttttcatcttttacaatccaaaccgagaaatcttgaagctttgcttgtaataatcagatttctaaagtcagcatatcataaagatagaaaactgatgcatatggaattaggaatgcttgatacacacacaagagaaccttttgttgtgatgagcaagaacactttcttgaatgcctattttttctacagattatctctaaattatatccccttgaaatatctatgcttccttcattgataacatactacaaagaatttggagtaaacctacacctccagagtctgaaattcttgttgtactacttagtagcttaaactgtactacctctatactgtctgatataccaaatgtcatgtcagagatgtttgtcgtcatatttaatgtggcagcagtatagcagctgacttatttggcatttgcacactgaagtctgcattttgaaggaatataagattatgggacaacctaattctacgcaaataatattcctgttctgatatgattagttctatcattgttacttcactgcctaatttagaaaatggcacagttaagttggataatttagtgcttgcggtggcaacattactttacatttgaaggccgttgaaaggacttgtaactcaaaagttattgactaatattaagctttgatttgagataaactcttactaagcatacgcacacgagaatgtgcattaacactttgttcctagtttgttaatgcccgtttaaggctttaaccttgttttgttttgaactgcatatgctattgcttaacttggtccagtaatatttagaaataatgttttacaccattttaactattgtgttgcttgacttgcttattttcccacctgcagatagagtaagctcaattcctatagttgacgataatggcgctctccttgatgtctactcgctcaggtttgatacataaccattttcttttgccatgctggtatgctgttttattctttcaaatcgatagaaccaatttaccttttgttcagtggtgcggttcacatgatgccattagtttgaactatcatttttggttgctcactggaattgaatttcgagtctatttgtttccacagtgatatcatggctctaggcaagaatgatgtctacactcgtattgagcttgaacaggtgacggtggagcatgtaagtccctactcttttcaattgtactcactaccttatctaacatgtatgtaaataaggagacctgcatattaattttgatgatcataaaaatgtgtggagagttttggaaagtggaaacctttttggggcgaaaaatgtaactgtgcttcaggcggaagcgggtctgtttttgccccaaataggtactccctccatttcatattgtaagacactttgacttttttctaagtcaagcttcttcaagtttaaccaagtttacagaaaaaatatagcaaaattttcgactccaaacaaacatactatcaaaatatattcagtgttatatttaatgaaactaatttggtgttgtaagagttgctacatttttctataacttgatcatacttatagaagtttgactttcaaaaagtcaaacagtcttataatccaaattctgaggtttggaaacctgaccagtttcagtctttctatctggttgctggtgctctgaccctggctgtgtgttagataaatagctagcaaaaggcttttctgtttagagatgtgctgtttatcaaatctgaaggaaaaacaaaacaagcaagctacaatattccaattctctttagcgctttccaattttgtgtccattccaattcactttgtatgttttcatttctgtatgacatgcatttagtgtttgcatttagacataacttatttggatccttttttagatactataattccacccaatctttcacactttaggccttggagctgcaataccaggtgaatggccgaagacactgtcatacctgcttgagcactagtaccttcctggaggttttggagcaattgtcagctccaggtacttctttatgcaatacatgtgaatccgctgtgcatcattacaggaaactgataaatcatatatttgtaatctaatttgaatttgagttgtgacaatctttgtgtctttgcaggggtgcggcgagtcgtcgttattgaaccaaggagcagatttgtgcaaggaataatctcattgagggacgcatttacatttctcattggataacatttgtgtagccagccattccatacatgaaaaaggtagttgtatttgattggaacaaaataaaaggaaaaaaaaagttatt</dnaseqindica>|
| |
| − | Link = [http://www.ncbi.nlm.nih.gov/nuccore/NM_001059222.2 RefSeq:Os04g0401300]|
| |
| − | }}
| |
| − | [[Category:Genes]] | |
| − | [[Category:Japonica mRNA]]
| |
| − | [[Category:Oryza Sativa Japonica Group]] | |
| − | [[Category:Japonica Genes]] | |
| − | [[Category:Japonica Chromosome 4]]
| |
| − | [[Category:Chromosome 4]]
| |
