Difference between revisions of "Os12g0502300"
(Created page with "{{JaponicaGene|
GeneName = Os12g0502300|
Description = Similar to Cyclin A-like protein (Fragment)|
Version = NM_001073360.1 GI:115488681 GeneID:4352280|
Length = 4968 bp|...") |
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| − | + | The rice '''''Os12g0502300''''' was reported as '''''Orysa;CycA2;1''''' in 2006 <ref name="ref1" /> by researchers from China. | |
| − | + | ==Annotated Information== | |
| − | + | ===Gene Symbol=== | |
| − | + | *'''''Os12g0502300''''' '''''<=>''''' '''''Orysa;CycA2;1''''' | |
| − | + | ===Function=== | |
| − | + | * Cyclins, the known activators for activity of CDKs, play crucial roles for cell cycle progression in eukaryotes.<ref name="ref1" /><ref name="ref2" /> | |
| − | + | * In plants, cyclin binding not only activates CDKs by inducing a configuration alteration at the catalytic sites, but also contributes to the subcellular localization and substrate specificity of the complex as well as regulation of protein stability.<ref name="ref1" /><ref name="ref2" /> | |
| + | ===Evolution=== | ||
| + | * Phylogenetic analysis indicated that both Arabidopsis and rice shared eight types of cyclins, A-, B-, D-, H-, L-, SDS-, T- and P-type, whereas C- and J18-type cyclins were specific to Arabidopsis, and F-type cyclins, lacking clear homologues in Arabidopsis, were unique to rice.<ref name="ref1" /> | ||
| + | ===Knowledge extension=== | ||
| + | * Similar to animals and yeasts, cell proliferation in plants is mainly controlled by a family of cyclin-dependent kinases (CDKs). The activity of CDKs is directly regulated by binding and activation of cyclins as well as other mechanisms that consist of protein phosphorylation/ dephosphorylation by specific kinases/phosphatases, proteolysis, CDK inhibitor protein (CKI) binding, etc. | ||
| + | * Cyclins were initially discovered in marine inverte-brates as proteins that accumulated at specific time points of the cell cycle and were subsequently degraded quickly.<ref name="ref1" /> | ||
| + | You can also add sub-section(s) at will. | ||
| + | ==Labs working on this gene== | ||
| + | * Rice Functional Genomics, Joint Laboratory of Temasek Life Sciences Laboratory of Singapore and Institute of Genetics and Developmental Biology | ||
| + | * Institute of Genetics and Developmental Biology, The Chinese Academy of Sciences, 100101 Beijing, China | ||
| + | * Rice Functional Genomics Group, Temasek Life Science Laboratory, 1 Research Link, The National University of Singapore, 117604 Singapore, Singapore | ||
| + | ==References== | ||
| + | <references> | ||
| + | * <ref name="ref1"> | ||
| + | La H, Li J, Ji Z, Cheng Y, Li X, Jiang S, Venkatesh PN, Ramachandran S. | ||
| + | Genome-wide analysis of cyclin family in rice (Oryza Sativa L.). Mol Genet | ||
| + | Genomics. 2006 Apr;275(4):374-86. Epub 2006 Jan 25. PubMed PMID: 16435118. | ||
| + | </ref> | ||
| + | * <ref name="ref2"> | ||
| + | Wang G, Kong H, Sun Y, Zhang X, Zhang W, Altman N, DePamphilis CW, Ma H. | ||
| + | Genome-wide analysis of the cyclin family in Arabidopsis and comparative | ||
| + | phylogenetic analysis of plant cyclin-like proteins. Plant Physiol. 2004 | ||
| + | Jun;135(2):1084-99. PubMed PMID: 15208425; PubMed Central PMCID: PMC514142. | ||
| + | </ref> | ||
| + | </references> | ||
| − | + | ==Structured Information== | |
| − | + | [[Category:Genes]][[Category:Oryza Sativa Japonica Group]][[Category:Japonica Chromosome 12]] | |
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| − | [[Category:Genes]] | ||
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| − | [[Category:Oryza Sativa Japonica Group]] | ||
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Latest revision as of 01:47, 30 March 2017
The rice Os12g0502300 was reported as Orysa;CycA2;1 in 2006 [1] by researchers from China.
Contents
Annotated Information
Gene Symbol
- Os12g0502300 <=> Orysa;CycA2;1
Function
- Cyclins, the known activators for activity of CDKs, play crucial roles for cell cycle progression in eukaryotes.[1][2]
- In plants, cyclin binding not only activates CDKs by inducing a configuration alteration at the catalytic sites, but also contributes to the subcellular localization and substrate specificity of the complex as well as regulation of protein stability.[1][2]
Evolution
- Phylogenetic analysis indicated that both Arabidopsis and rice shared eight types of cyclins, A-, B-, D-, H-, L-, SDS-, T- and P-type, whereas C- and J18-type cyclins were specific to Arabidopsis, and F-type cyclins, lacking clear homologues in Arabidopsis, were unique to rice.[1]
Knowledge extension
- Similar to animals and yeasts, cell proliferation in plants is mainly controlled by a family of cyclin-dependent kinases (CDKs). The activity of CDKs is directly regulated by binding and activation of cyclins as well as other mechanisms that consist of protein phosphorylation/ dephosphorylation by specific kinases/phosphatases, proteolysis, CDK inhibitor protein (CKI) binding, etc.
- Cyclins were initially discovered in marine inverte-brates as proteins that accumulated at specific time points of the cell cycle and were subsequently degraded quickly.[1]
You can also add sub-section(s) at will.
Labs working on this gene
- Rice Functional Genomics, Joint Laboratory of Temasek Life Sciences Laboratory of Singapore and Institute of Genetics and Developmental Biology
- Institute of Genetics and Developmental Biology, The Chinese Academy of Sciences, 100101 Beijing, China
- Rice Functional Genomics Group, Temasek Life Science Laboratory, 1 Research Link, The National University of Singapore, 117604 Singapore, Singapore
References
- ↑ 1.0 1.1 1.2 1.3 1.4 La H, Li J, Ji Z, Cheng Y, Li X, Jiang S, Venkatesh PN, Ramachandran S. Genome-wide analysis of cyclin family in rice (Oryza Sativa L.). Mol Genet Genomics. 2006 Apr;275(4):374-86. Epub 2006 Jan 25. PubMed PMID: 16435118.
- ↑ 2.0 2.1 Wang G, Kong H, Sun Y, Zhang X, Zhang W, Altman N, DePamphilis CW, Ma H. Genome-wide analysis of the cyclin family in Arabidopsis and comparative phylogenetic analysis of plant cyclin-like proteins. Plant Physiol. 2004 Jun;135(2):1084-99. PubMed PMID: 15208425; PubMed Central PMCID: PMC514142.
