Difference between revisions of "Os02g0535400"
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==Annotated Information== | ==Annotated Information== | ||
===Function=== | ===Function=== | ||
| − | The gene locus Os02g0535400 is a gene called Os RAR1([http://www.ncbi.nlm.nih.gov/gene/?term=AK111881 NCBI Gene ID: 4329567]) and this gene codes a protein called Cysteine and histidine-rich domain-containing protein RAR1( [http://www.ncbi.nlm.nih.gov/protein/Q6EPW7.2 NCBI ACCESSION:Q6EPW7])<ref name = "ref 1"/>. RAR1 is an important component in innate immunity in Rice. RAR1 is required for basal resistance against compatible races of rice blast and bacterial blight and this resistance is mediated by Os Rac1. Interestingly, Os RAR1is not required by the three examined riceRgenes for blast resistance. Recently, it was shown that OsRAR1is not required for Pish-mediated blast resistance<ref name = "ref 2"/>. RAR1 is critical for Os Rac1–mediated enhancement of PAMP signaling. Therefore, RAR1 activity in rice innate immunity may be on a broader scale than in those other species. | + | The gene locus Os02g0535400 is a gene called Os RAR1([http://www.ncbi.nlm.nih.gov/gene/?term=AK111881 NCBI Gene ID: 4329567]) and this gene codes a protein called Cysteine and histidine-rich domain-containing protein RAR1( [http://www.ncbi.nlm.nih.gov/protein/Q6EPW7.2 NCBI ACCESSION:Q6EPW7])<ref name = "ref 1"/>. RAR1 (for required for ''Mla12'' resistance) is an important component of ''R'' gene–mediated disease resistance, which contains two zinc binding finger motifs termed CHORD-I and |
| + | CHORD-II (Cys- and His-rich domains). In plants, RAR1 interacts directly with SGT1 (for suppressor of the G2 allele of ''skp1'') and HSP90. The CHORD-I domain of RAR1 interacts directly with the N terminus of HSP90, and SGT1 binds the CHORD-II domain of RAR1. SGT1 is required for disease resistance mediated by diverse R proteins and is also required for the function of an SCF (for Skp1/Cullin/F-box protein). RAR1, SGT1, and HSP90 were shown to play an important role in regulating the stability of R proteins that contain the NBS-LRR domain<ref name = "ref 1"/>. | ||
| + | RAR1 is an important component in innate immunity in Rice. RAR1 is required for basal resistance against compatible races of rice blast and bacterial blight and this resistance is mediated by Os Rac1. Interestingly, Os RAR1is not required by the three examined riceRgenes for blast resistance. Recently, it was shown that OsRAR1is not required for Pish-mediated blast resistance<ref name = "ref 2"/>. RAR1 is critical for Os Rac1–mediated enhancement of PAMP signaling. Therefore, RAR1 activity in rice innate immunity may be on a broader scale than in those other species. | ||
===Expression=== | ===Expression=== | ||
Revision as of 10:27, 10 June 2014
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Contents
Annotated Information
Function
The gene locus Os02g0535400 is a gene called Os RAR1(NCBI Gene ID: 4329567) and this gene codes a protein called Cysteine and histidine-rich domain-containing protein RAR1( NCBI ACCESSION:Q6EPW7)[1]. RAR1 (for required for Mla12 resistance) is an important component of R gene–mediated disease resistance, which contains two zinc binding finger motifs termed CHORD-I and CHORD-II (Cys- and His-rich domains). In plants, RAR1 interacts directly with SGT1 (for suppressor of the G2 allele of skp1) and HSP90. The CHORD-I domain of RAR1 interacts directly with the N terminus of HSP90, and SGT1 binds the CHORD-II domain of RAR1. SGT1 is required for disease resistance mediated by diverse R proteins and is also required for the function of an SCF (for Skp1/Cullin/F-box protein). RAR1, SGT1, and HSP90 were shown to play an important role in regulating the stability of R proteins that contain the NBS-LRR domain[1]. RAR1 is an important component in innate immunity in Rice. RAR1 is required for basal resistance against compatible races of rice blast and bacterial blight and this resistance is mediated by Os Rac1. Interestingly, Os RAR1is not required by the three examined riceRgenes for blast resistance. Recently, it was shown that OsRAR1is not required for Pish-mediated blast resistance[2]. RAR1 is critical for Os Rac1–mediated enhancement of PAMP signaling. Therefore, RAR1 activity in rice innate immunity may be on a broader scale than in those other species.
Expression
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Evolution
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Labs working on this gene
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References
- ↑ 1.0 1.1 Thao NP, Chen L, Nakashima A, Hara S, Umemura K, Takahashi A, Shirasu K, Kawasaki T, Shimamoto K.RAR1 and HSP90 form a complex with Rac/Rop GTPase and function in innate-immune responses in rice.Plant Cell. 2007 Dec;19(12):4035-45.
- ↑ Takahashi, A., Agrawal, G.K., Yamazaki, M., Onosato, K., Miyao, A., Kawasaki, T., Shimamoto, K., and Hirochika, H. (2007). Rice Pti1a negatively regulates RAR1-dependent defense responses. Plant Cell 9: 2940–2951.
Structured Information
| Gene Name |
Os02g0535400 |
|---|---|
| Description |
Conserved hypothetical protein |
| Version |
NM_001053574.1 GI:115446518 GeneID:4329567 |
| Length |
2767 bp |
| Definition |
Oryza sativa Japonica Group Os02g0535400, complete gene. |
| Source |
Oryza sativa Japonica Group ORGANISM Oryza sativa Japonica Group
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP
clade; Ehrhartoideae; Oryzeae; Oryza.
|
| Chromosome | |
| Location |
Chromosome 2:20584982..20587748 |
| Sequence Coding Region |
20586274..20586295,20587512..20587747 |
| Expression | |
| Genome Context |
<gbrowseImage1> name=NC_008395:20584982..20587748 source=RiceChromosome02 preset=GeneLocation </gbrowseImage1> |
| Gene Structure |
<gbrowseImage2> name=NC_008395:20584982..20587748 source=RiceChromosome02 preset=GeneLocation </gbrowseImage2> |
| Coding Sequence |
<cdnaseq>gtagagactagagaggccacaggcggcggcggcagcagcggaagtctctcgtctcgtccgtggagaaagggggaagacgaagatgtcgacggaggcggagaccaccagcgccgccgcccccgcccccgcccccgcccccgcatcggcgccggcgcggtgccagcggataggctgcgacgccacgttcaccgacgacaacaaccccgacggctcctgccaataccacccctccgtgacctatgtttcatgatggcatga</cdnaseq> |
| Protein Sequence |
<aaseq>VETREATGGGGSSGSLSSRPWRKGEDEDVDGGGDHQRRRPRPRP RPRIGAGAVPADRLRRHVHRRQQPRRLLPIPPLRDLCFMMA</aaseq> |
| Gene Sequence |
<dnaseqindica>1454..1475#2..237#agtagagactagagaggccacaggcggcggcggcagcagcggaagtctctcgtctcgtccgtggagaaagggggaagacgaagatgtcgacggaggcggagaccaccagcgccgccgcccccgcccccgcccccgcccccgcatcggcgccggcgcggtgccagcggataggctgcgacgccacgttcaccgacgacaacaaccccgacggctcctgccaataccacccctccgtgagtcctcctcctccccttcttccccttctaaatctcatggggtctaactaattgccccgcggattacgggagtggaggagtctgttcttctagggggaagttgggcagttcgaatctgtaatggcggggtcaagggcttcgcctgctcttgggaaacttctggggacgaattgggcagcggggaatatttgagttctatatacaataatgaaatttagtgtcatatagagatatgttggactacactcattactcatagtagattagtggattggattgcacgattatactcatagtagattagtagattagtggattggattacacgattcaatcagaagggttattgatgccattggcaaaaggtattgtagttgtcgcaaacacgtgatattaggtggttttttttttgccccttatttgggttaggatattggtaccttgaagctgcctcttgatgaggcatcatgggcaatgtgtctgatgtgtggcgagggatttttttcccctttggatatggctcacatgagtgctgactatttacaaaaagcaaaaggaaaagaggcaaagaactacctttcccttcagagagtaaacaaaattaatttggaataaagatatgacattctctttctctttctctttttcaatccctaccgtgtctaagggtcagatacccatgttgtaccaaaaaaggattaagtacacaaacagctgctgcaaaacttcttcacaacttcttctatttccaattgtgaatatctcttgataacaatggaagaaataatggttaattttttcaagcaattcttttcttttgtctccaaagattcaaatcacattgctaactttgtgatgccatgccaaattccattgtaatatttaaacaccaaattcacactcatgtttactgcatttggtctagaagaaatacacaacagctagtataagagaatacctaaatgtggtcccattcttttttggaaaatgacgaataaagcaacatatttaaacaagactcgtataatatgtttgctaactctctttatggtttcttgtctactgccaaatactatatttatttccaattttccactgtagtgttctgaccactgtctccttttttttttcttgcagggagtaagtgtttcttctttgcatgagagggtacttctagaaggatgcataggttaattttctaagattttttttttcagcctatgtttcatgatggcatgaaacagtggagttgctgtaagcaaaaaagccatgattttagcctatttttggctattcctgggtaaggatccctctctagtatttccttttcacagcatgcacccacaacataagtcaactatgtgctatcaacctgaacattaccatctgggctggcctgttgtgtattttagcaaaaccaagcatgaatgcatgaatcgtatgctgtactgctgtgtaggtgcaaaactggaaagcacacaactgagaaaccaatcacaaaagcagttcctactaaaccatcaaaggcagttccagtccagacttcgaagcagagtgtgggagctgacacttgctcaaggtgccgtcaaggtttcttttgctctgaccatggtgagtttctgtctataagcataatgcttggatacaactgattgatcccctatttgggtgtaacagctgattgtttcgttattattttaacgactgacatccctatgcatttttatgtgttgatagaataaatcgtaacttttaatttaacagattatgcactgctattttttcaggatcacaacccaaggcacaaataccaaccgctaccagtgatactaacatggtacctgttgagaagcctgcagttccaccaccaaagaaaaaaattgatctgaatgagcctagggtttgtaagaacaaaggatgtggtaaaacctacaaggagaaggataatcatgatgaagcatgcgattaccatccaggacctgcagtttttcgcgacaggattagaggggtatgtttttggttcaaacttattgttgttttgctctattccttgatttttgccatcactgactctgacatctttttaaaaatttttgcagtggaaatgttgtgatattcatgtcaaggaatttgatgaatttatggagatccctccgtgcacaaagggttggcacaatgctgatgccgcatgaattttcaccatgccccatcttggaataagaaccctattagcataaggttctcttgtatctcgtagtgcataaggtgcaatttttatggagaattttacttggagttggggagtgtggcaaagataccgagaataggctgttttaccgtgctctgtgtgactgctgcaaaagtgtgcgtggtgtttcattttttgtctgaaacggggacttgaaattgtgtgtggagacttcggtctcgttcgttggctcgttgccaattcttcatagttagaaaatcaaatgctccatctaaatgctatcctgcagacttttggtaacacccatctttctgtttatatg</dnaseqindica> |
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