Difference between revisions of "HSF"
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* Heat shock transcription factors (HSFs) play an important role in the physiological response to heat stress by regulating the expression of heat-responsive genes during the initial stages of heat stress <ref name="ref1" /><ref name="ref2" /><ref name="ref3" /><ref name="ref4" /><ref name="ref5" />. They are the primary molecules responsible for rapid relaying signals of cellular stress to the transcriptional apparatus and activating the expression of the HSP genes<ref name="ref4" />. | * Heat shock transcription factors (HSFs) play an important role in the physiological response to heat stress by regulating the expression of heat-responsive genes during the initial stages of heat stress <ref name="ref1" /><ref name="ref2" /><ref name="ref3" /><ref name="ref4" /><ref name="ref5" />. They are the primary molecules responsible for rapid relaying signals of cellular stress to the transcriptional apparatus and activating the expression of the HSP genes<ref name="ref4" />. | ||
| + | [[File:HSF_Os05g0530400.png|center|thumb|1000px|'''Figure 1.''' ''Protein Structure of '''Os05g0530400''''']] | ||
* HSFs have a modular structure with a highly conserved HSF domain consisited of a helix-turn-helix(H2-T-H3) motif in the N-terminal region. Connnected to the Cterminal activation domain is an adjacent domain with heptad hydrophobic repeats A/B involved in oligomerization, a nuclear localization signal. After that located a lysine residues serving as nuclear localization signal(NLS), which is required for nuclear import<ref name="ref2" /><ref name="ref4" /><ref name="ref5" />. | * HSFs have a modular structure with a highly conserved HSF domain consisited of a helix-turn-helix(H2-T-H3) motif in the N-terminal region. Connnected to the Cterminal activation domain is an adjacent domain with heptad hydrophobic repeats A/B involved in oligomerization, a nuclear localization signal. After that located a lysine residues serving as nuclear localization signal(NLS), which is required for nuclear import<ref name="ref2" /><ref name="ref4" /><ref name="ref5" />. | ||
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*'''Pfam: [http://pfam.janelia.org/family/PF00447 PF00447]''' | *'''Pfam: [http://pfam.janelia.org/family/PF00447 PF00447]''' | ||
Revision as of 15:56, 12 June 2013
Brief Introduction
- Heat shock transcription factors (HSFs) play an important role in the physiological response to heat stress by regulating the expression of heat-responsive genes during the initial stages of heat stress [1][2][3][4][5]. They are the primary molecules responsible for rapid relaying signals of cellular stress to the transcriptional apparatus and activating the expression of the HSP genes[4].
- HSFs have a modular structure with a highly conserved HSF domain consisited of a helix-turn-helix(H2-T-H3) motif in the N-terminal region. Connnected to the Cterminal activation domain is an adjacent domain with heptad hydrophobic repeats A/B involved in oligomerization, a nuclear localization signal. After that located a lysine residues serving as nuclear localization signal(NLS), which is required for nuclear import[2][4][5].
- Pfam: PF00447
Japonica Group
Indica Group
References
- ↑ Mittal D, Chakrabarti S, Sarkar A, et al. Heat shock factor gene family in rice: genomic organization and transcript expression profiling in response to high temperature, low temperature and oxidative stresses[J]. Plant Physiology and Biochemistry, 2009, 47(9): 785-795.
- ↑ 2.0 2.1 Guo J, Wu J, Ji Q, et al. Genome-wide analysis of heat shock transcription factor families in rice and Arabidopsis[J]. Journal of genetics and genomics= Yi chuan xue bao, 2008, 35(2): 105.
- ↑ 1: Chung E, Kim KM, Lee JH. Genome-wide analysis and molecular characterization of heat shock transcription factor family in Glycine max. J Genet Genomics. 2013 Mar 20;40(3):127-35. doi: 10.1016/j.jgg.2012.12.002. Epub 2012 Dec 28. PubMed PMID: 23522385.
- ↑ 4.0 4.1 4.2 Jin G H, Gho H J, Jung K H. A systematic view of rice heat shock transcription factor family using phylogenomic analysis[J]. Journal of plant physiology, 2012.
- ↑ 5.0 5.1 Lin Y X, Jiang H Y, Chu Z X, et al. Genome-wide identification, classification and analysis of heat shock transcription factor family in maize[J]. BMC genomics, 2011, 12(1): 76.
